Incidence, clinical characteristics, and outcome after unexpected cardiac arrest among critically ill adults with COVID-19: insight from the multicenter prospective ACICOVID-19 registry

Chelly, Jonathan; Plantefève, Gaëtan; Kamel, Toufik; Bruel, Cédric; Nseir, Saad; Lai, Christopher; Cirillo, Giulia; Skripkina, Elena; Ehrminger, Sebastien; Berdaguer-Ferrari, Fernando-Daniel; Marec, Julien Le; Paul, Marine; Autret, A.; Deye, Nicolas; Arnal, Jean-Michel; Badié, Julio; Berric, Audrey; Brunet, J.; Bertrand, Thibault; Carpentier, Dorothée; Chaoui, K.; Chapelle, Anaïs; Chelha, Riad; Corno, Gaëlle; Daubin, Cédric; Descamps, Richard; Demoule, Alexandre; Deryckere, Stephanie; Donati, Stephane-Yannis; Ducros, Laurent; Embriaco, Nathalie; Engrand, Nicolas; Foucault, Camille; Freeman, Sean Anthony; Ramos, Santiago Freita; Galbois, Arnaud; Garnero, Aude; Geay, Cyrille; Guérin, Laurent; Ha, Vivien Hong Tuan; Hullin, Thomas; Jochmans, Sébastien; Kaidomar, Michel; Kelway, Charlotte; Labruyère, Marie; Larcher, Romaric; Legriel, Stéphane; Leloup, Maxime; Lesieur, Olivier; Malissin, Isabelle; Mazerand, Sandie; Mégarbane, Bruno; Melone, Marie-Anne; Menoret, Edouard; Metzelard, Matthieu; Vong, Ly Van Phack; Persichini, Romain; Pichon, Nicolas; Gil, Santiago; Quenot, Jean-Pierre; Roux, Damien; Schnell, David; Sigaud, Florian; Suply, Clement; Sztrymf, Benjamin; Terzi, Nicolas; Thévenin, Didier; Voicu, Sébastian

doi:10.1186/s13613-021-00945-y

Cited by 7 publications

(3 citation statements)

References 33 publications

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“…Up to 74% of these in-hospital cardiac arrests occur in ICU patients [ 41 •]. Prior history of coronary artery disease, atrial fibrillation/flutter, cerebrovascular disease, hypertension, HF, chronic kidney disease [ 41 •, 42 , 43 ], and diabetes mellitus [ 43 , 44 ] are major risk factors for patients with in-hospital CA. The 30-day mortality rate was lower among in-hospital CA patients than out of hospital CA patients with COVID-19 [ 44 ].…”

Section: Rapid Dissemination Of Informationmentioning

confidence: 99%

Cardiac Registries During the COVID-19 Pandemic: Lessons Learned

et al. 2022

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Purpose of this Review We discuss the role of observational studies and cardiac registries during the COVID-19 pandemic. We focus on published cardiac registries and highlight contributions to the field that have had clinical implications. Recent Findings We included observational studies of COVID-19 patients published in peer-reviewed medical journals with defined inclusion and exclusion criteria, defined study design, and primary outcomes. A PubMed and MEDLINE literature review results in 437 articles, of which 52 include patients with COVID-19 with cardiac endpoints. From July 2020 to December 2021, the average time from last data collected to publication was 8.9 ± 4.1 months, with an increasing trend over time ( R = 0.9444, p < 0.0001). Of the 52 articles that met our inclusion criteria, we summarize main findings of 4 manuscripts on stroke, 14 on acute coronary syndrome, 4 on cardiac arrest, 7 on heart failure, 7 on venous thromboembolism, 5 on dysrhythmia, and 11 on different populations at risk for cardiovascular. Summary Registries are cost effective, not disruptive to essential health services, and can be rapidly disseminated with short intervals between last data point collected and publication. In less than 2 years, cardiac registries have filled important gaps in knowledge and informed the care of COVID-19 patients with cardiovascular conditions. Supplementary Information The online version contains supplementary material available at 10.1007/s11886-022-01686-5.

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Section: Rapid Dissemination Of Informationmentioning

confidence: 99%

Cardiac Registries During the COVID-19 Pandemic: Lessons Learned

et al. 2022

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“…Absence of N20 response in comatose cardiac arrest patients with hypoxic ischemic brain injury remains one of the most reliable early prognostic tools for predicting poor neurological outcome [70]. As cardiac arrest is common (8%) in COVID-19 ICU patients [71], SSEP can be a useful tool in that specific population.…”

Section: Somatosensory Evoke Potentialsmentioning

confidence: 99%

Treating the body to prevent brain injury: lessons learned from the coronavirus disease 2019 pandemic

Fan

Solnicky

Cho

2022

Current Opinion in Critical Care

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Purpose of reviewWe aim to provide the current evidence on utility and application of neuromonitoring tools including electroencephalography (EEG), transcranial Doppler (TCD), pupillometry, optic nerve sheath diameter (ONSD), cerebral near-infrared spectroscopy (cNIRS), somatosensory-evoked potentials (SSEPs), and invasive intracranial monitoring in COVID-19. We also provide recent evidence on management strategy of COVID-19-associated neurological complications. Recent findingsDespite the common occurrence of neurological complications, we found limited use of standard neurologic monitoring in patients with COVID-19. No specific EEG pattern was identified in COVID-19. Frontal epileptic discharge was proposed to be a potential marker of COVID-19 encephalopathy. TCD, ONSD, and pupillometry can provide real-time data on intracranial pressure. Additionally, TCD may be useful for detection of acute large vessel occlusions, abnormal cerebral hemodynamics, cerebral emboli, and evolving cerebral edema at bedside. cNIRS was under-utilized in COVID-19 population and there are ongoing studies to investigate whether cerebral oxygenation could be a more useful parameter than peripheral oxygen saturation to guide clinical titration of permissive hypoxemia. Limited data exists on SSEPs and invasive intracranial monitoring. SummaryEarly recognition using standardized neuromonitoring and timely intervention is important to reduce morbidity and mortality. The management strategy for neurological complications is similar to those without COVID-19.

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“…Endotracheal tube occlusions were the second cause of unexpected cardiac arrests in mechanically ventilated COVID-19 patients, frequently associated with unfavorable outcome 13 . This complication is related to under-humidification of the gases delivered to patients 14,15 .…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the Humidification Performances of New Generation of Heated Wire Humidifiers

Lellouche,

Rousseau,

Bouchard

2023

Respir Care

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BackgroundAt high ambient temperatures in ICU rooms, the humidification performances of heated wire humidifiers (HH) are significantly reduced, with delivered gas humidity well below 30 mgH 2 O/L leading to an increased risk of endo-tracheal occlusions, sub-occlusions or mucociliary dysfunction.The objective of the study was to evaluate the humidity delivered at the Y-piece with new generation HH with advanced algorithm (FP950 and VHB20) while varying ambient temperatures. MethodsWe measured on bench the hygrometry of inspiratory gases delivered by new generation of HH (i) FP950 (Fisher&Paykel Healthcare) (ii) VHB20 (Vincent Medical) and previous generation of HH (iii) MR850 with usual settings (37 at the chamber/40 at the Y piece) (iv) MR 850 with no temperature gradient (40/40), and (v) MR850 with automatic compensation algorithm activated. Hygrometry was measured with the psychrometric method after one hour of stability while varying the room temperature from 20 to 30°C. ResultsTwo hundred and ninety-four hygrometric bench measurements were performed at steady state for the different tested conditions. With the new HH (FP950 and VHB20), gas humidity delivered remained above 30 mgH 2 O/L in all tested conditions, even at high ambient temperatures (> 25°C).With previous generation of HH (MR850), at high ambient temperature, humidity delivered was adequate in only 26% (11/42) of the measurements when usual settings were used (37/40) and 30% (11/37) with automatic compensation. When no temperature gradient was set (40/40), humidity delivered was above 30 mgH 2 O/L in 91% (30/33) of the measurements at high ambient temperature.With ambient temperature below 25°C, almost all devices and settings provided adequate humidity. ConclusionThe new FP950 and VHB20 heated wire heated humidifiers using advanced algorithms have demonstrated stable performance while varying the ambient temperature by 20-30°C, better than the previous generation of heated humidifiers when ambient temperatures were high.

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Incidence, clinical characteristics, and outcome after unexpected cardiac arrest among critically ill adults with COVID-19: insight from the multicenter prospective ACICOVID-19 registry

Cited by 7 publications

References 33 publications

Cardiac Registries During the COVID-19 Pandemic: Lessons Learned

Cardiac Registries During the COVID-19 Pandemic: Lessons Learned

Treating the body to prevent brain injury: lessons learned from the coronavirus disease 2019 pandemic

Evaluation of the Humidification Performances of New Generation of Heated Wire Humidifiers

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