Incidence, characteristics, and outcome of out-of-hospital cardiac arrest in Italy: A systematic review and meta-analysis

Scquizzato, Tommaso; Gamberini, Lorenzo; D’Arrigo, Sonia; Galazzi, Alessandro; Babini, Giovanni; Losiggio, Rosario; Imbrìaco, Guglielmo; Fumagalli, Francesca; Cucino, Alberto; Landoni, Giovanni; Scapigliati, Andrea; Ristagno, Giuseppe; Semeraro, Federico; Bertoncello, Francesco; Canalini, Alberto; Colelli, Stefano; Conti, Giuseppe; Giacometti, Maurizio; Giuliani, Giovanni; Graziano, Alessandro Di; Mina, Andrea; Orazio, S; Paoli, Andrea; Peratoner, Alberto; Pegani, Carlo; Roncarati, A.; Sabetta, Cesare; Savastano, Simone; Stella, Federica; Varutti, Rosanna; Verginella, Francesca; Zuliani, Michele

doi:10.1016/j.resplu.2022.100329

Cited by 10 publications

(9 citation statements)

References 52 publications

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“…Most of these data are comparable to the ones of a recently published meta-analysis of 42 studies on OHCA in Italy published between 1995 and 2022 [4]. This meta-analysis showed low rates of bystander CPR and use of AED, which in our study is confirmed in a more homogeneous setting.…”

Section: Main Findingssupporting

confidence: 90%

“…This prompted the European Society of Cardiology to include in the 2022 guidelines, a class I recommendation for an improvement in public access to defibrillators, the promotion of CPR by bystanders, and the training of the general population in basic life support [3]. Furthermore, there is a paucity of data on OHCA and heterogeneity in reporting [4,5], even in the same nation [4]. In addition, the coronavirus disease (COVID-19) pandemic has become an important additional variable affecting the public health system with a strong impact on OHCA [6].…”

Section: Introductionmentioning

confidence: 99%

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What Else Is Needed to Improve Survival from Out-of-Hospital Cardiac Arrest to Hospital Admission? Data from a Prospective Registry for the Years 2020–2023 in the Italian Province of Varese

De Ponti,

Arnò,

Piemonti

et al. 2023

JCM

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Around the world, data on out-of-hospital cardiac arrest (OHCA) are heterogeneous in terms of outcomes and reporting, and not all registries follow the Utstein recommendations for uniform OHCA data collection. This study reports data on OHCA occurring in recent years in a limited territory to analyze, in a homogenous setting, the circumstances and interventions affecting survival to hospital admission. OHCA data from the province of Varese for the years 2020–2022 were extracted from a prospective registry. For survival to hospital admission, the impact of pandemic waves and variables known to affect survival was evaluated both in the overall population and in the subgroup of patients in whom cardiopulmonary resuscitation (CPR) was initiated or continued by the emergency medical service (EMS). Overall, 3263 OHCAs occurred mainly at home (88%), with a time to intervention of 13.7 min, which was significantly longer during lockdown (15.7 min). Bystanders performed CPR in 22% of the cases and used automatic external defibrillator (AED) in 2.2% of the cases. Overall survival to hospital admission was 7.7%. In the multivariate analysis, in the general population, occurrence near a public building (OR 1.92), the presence of witnesses (OR 2.65), and a shockable rhythm (OR 7.04) were independent predictors of survival to hospital admission, whereas age (OR 0.97) and occurrence during a pandemic wave (OR 0.62) were associated with significantly worse survival to hospital admission. In the group of patients who received CPR, AED shock by bystanders was the only independent predictor of survival (OR 3.14) to hospital admission. Among other factors, early defibrillation was of crucial importance to improve survival to hospital admission in possibly rescuable patients. The occurrence of OHCA during pandemic waves was associated with longer intervention time and worse survival to hospital admission.

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Section: Main Findingssupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

What Else Is Needed to Improve Survival from Out-of-Hospital Cardiac Arrest to Hospital Admission? Data from a Prospective Registry for the Years 2020–2023 in the Italian Province of Varese

De Ponti,

Arnò,

Piemonti

et al. 2023

JCM

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“…In Italy, despite data are not uniformly collected, OHCA occurs with an estimated incidence of 86 per 100 000 population in keeping with other European countries. About 50% of cardiac arrest are treated by the Emergency Medical System, the pooled survival rate is 9.0–9.5% and ROSC is 19% in line with international registry [12]. In other terms, survival occurs in one in every 10 patients and only one in every 20 has a favorable neurological outcome.…”

mentioning

confidence: 90%

Out of hospital cardiac arrest and organ donation: the innovative approach for emergency physicians

Lazzeri,

Manuela,

Peris

2023

European Journal of Emergency Medicine

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“…Out-of-hospital cardiac arrest (OHCA) is a major health problem worldwide. 1 , 2 , 3 In Italy, emergency medical services (EMS)-attended OHCA occurs with an estimated incidence of 86 per 100,000 population per year 4 . In the metropolitan area of Milan, Italy, a region of five million people with a population density of 2500 people/km 2 , 14 individuals suffers an OHCA each day.…”

Section: Introductionmentioning

confidence: 99%

Extracorporeal cardiopulmonary resuscitation for refractory out-of-hospital cardiac arrest: 10-year experience in a metropolitan cardiac arrest centre in Milan, Italy

Scquizzato,

Calabrò,

Franco

et al. 2024

Resuscitation Plus

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Incidence, characteristics, and outcome of out-of-hospital cardiac arrest in Italy: A systematic review and meta-analysis

Cited by 10 publications

References 52 publications

What Else Is Needed to Improve Survival from Out-of-Hospital Cardiac Arrest to Hospital Admission? Data from a Prospective Registry for the Years 2020–2023 in the Italian Province of Varese

What Else Is Needed to Improve Survival from Out-of-Hospital Cardiac Arrest to Hospital Admission? Data from a Prospective Registry for the Years 2020–2023 in the Italian Province of Varese

Out of hospital cardiac arrest and organ donation: the innovative approach for emergency physicians

Extracorporeal cardiopulmonary resuscitation for refractory out-of-hospital cardiac arrest: 10-year experience in a metropolitan cardiac arrest centre in Milan, Italy

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