Incidence and Treatment Patterns in Hospitalizations for Malignant Spinal Cord Compression in the United States, 1998–2006

Mak, Kimberley S.; Lee, Leslie K.; Mak, Raymond H.; Wang, Shuang; Pile‐Spellman, John; Abrahm, Janet L.; Prigerson, Holly G.; Balboni, Tracy A.

doi:10.1016/j.ijrobp.2010.03.022

Cited by 106 publications

(61 citation statements)

References 28 publications

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“…More than one third of all included studies were from the United States (n = 28) [18,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62]; roughly 13% of studies were conducted in Canada (n = 10) [17,63,64,65,66,67,68,69,70,71], 5% in Israel (n = 4) [72,73,74,75], 5% in Australia (n = 4) [9,76,77,78]; 4% in France (n = 3) [79,80,81]; 4% from Norway (n = 3) [7,10,19]; while the remaining were from countries including Brazil, China, Estonia, Finland, Greece, Germany, Iceland, Italy, Japan, the Netherlands, Nigeria, Poland, Scotland, Sierra Leone, South Africa, Sweden, Taiwan, and the United Kingdom (see online suppl. table; for all online suppl.…”

Section: Resultsmentioning

confidence: 99%

“…table) [62]. A majority of studies involved traumatic SCI (TSCI) (n = 68), but a few studies were also included that considered non-traumatic SCI (NTSCI) only (n = 7) [43,48,69,75,76,85,86], or both NTSCI and TSCI (n = 3) [40,41,96] (see online suppl. table).…”

Section: Resultsmentioning

confidence: 99%

“…table). For those studies that reported the mean age, the mean age ranged between 23 and 62 [74,106] and between 48 [75] and 62 [48] among studies with adult TSCI and NTSCI populations. Among pediatric populations, the mean age was 11.8 for a TSCI-only population (among one year survivors-only) [83], and 5 years in an NTSCI population [86].…”

Section: Resultsmentioning

confidence: 99%

“…For two adult NTSCI populations, in-hospital mortality varied between 9.6 and 11.4% [48,76] and was 7.2% for a pediatric population [86.] Median survival ranged between 0.16 [85] and 24 years [75], one-year survival between 19.7 and 99.4% [69,75], 5-year survival was 93.7%, 10-year survival 84.2%, 20-year survival 49.8%, 30-year survival of 39.3% [75].…”

Section: Resultsmentioning

confidence: 99%

“…Studies reporting on factors affecting survival following an NTSCI diagnosis found age at lesion onset, sex, severity of lesion, and tumor site to be important predictors [43,69,75]. One study investigated trends in survival and found improvement in survival for NTSCI, albeit only in the past decade [75], while another study found no evidence of improvement in the risk of in-hospital mortality over time [48]. …”

Section: Resultsmentioning

confidence: 99%

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Mortality and Longevity after a Spinal Cord Injury: Systematic Review and Meta-Analysis

Chamberlain

Meier²,

Mader³

et al. 2015

Neuroepidemiology

135

101

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Background/Aims: Mortality and longevity studies of spinal cord injury (SCI) are essential for informing healthcare systems and policies. This review evaluates the current evidence among people with SCIs worldwide in relation to the WHO region and country income level; demographic and lesion characteristics; and in comparison with the general population. Methods: A systematic review of relevant databases for original studies. Pooled estimates were derived using random effects meta-analysis, restricted to traumatic SCI. Results: Seventy-four studies were included. In-hospital mortality varied, with pooled estimates of 24.1% (95% confidence interval (CI) 14.1-38.0), 7.6% (95% CI 6.3-9.0), 7.0% (95% CI 1.5-27.4), and 2.1% (95% CI 0.9-5.0) in the WHO regions of Africa, the Americas, Europe and Western Pacific. The combined estimate for low- and middle-income countries was nearly three times higher than for high-income countries. Pooled estimates of first-year survival were 86.5% (95% CI 75.3-93.1), 95.6% (95% CI 81.0-99.1), and 94.0% (95% CI 93.3-94.6) in the Americas, Europe and Western Pacific. Pooled estimates of standardized mortality ratios in tetraplegics were 2.53 (2.00-3.21) and 2.07 (1.47-2.92) in paraplegics. Conclusion: This study found substantial variation in mortality and longevity within the SCI population, compared to the general population, and between WHO regions and country income level. Improved standardization and quality of reporting is needed to improve inferences regarding the extent to which mortality outcomes following an SCI are related to healthcare systems, services and policies.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

Mortality and Longevity after a Spinal Cord Injury: Systematic Review and Meta-Analysis

Chamberlain

Meier²,

Mader³

et al. 2015

Neuroepidemiology

135

101

View full text Add to dashboard Cite

show abstract

Diagnosis and treatment of epidural metastases

Yáñez

Miller

Batchelor

2016

Cancer

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Epidural metastases occur in 5% to 10% of cancer patients and represent a neurological emergency. Patients most commonly present with an acute onset of motor weakness, and restoration of neurological function is critically dependent on prompt diagnosis and treatment. This review discusses the clinical, epidemiological, and radiological features associated with epidural metastases and resulting spinal cord compression. Moreover, current treatment paradigms are reviewed. The timely initiation of radiation as well as surgery in select cases is critical for preserving neurological function and achieving local tumor control and pain control. Future studies investigating surgical and radiation treatment for metastatic epidural cord compression are urgently needed. Cancer 2017;123:1106-1114. © 2016 American Cancer Society.

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Neurologic complications of lung cancer

Daly

Lee

2020

Cancer

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Lung cancer and its associated treatments can cause various neurologic complications, including brain and leptomeningeal metastases, epidural spinal cord compression, cerebrovascular events, and treatment-related neurotoxicities. Lung cancer care has significantly changed in the last 5 to 10 years, with novel therapies that have affected aspects of neurologic complication management. Herein, the authors review the potential neurologic complications of lung cancer, including important clinical and therapeutic aspects of care.

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Incidence and Treatment Patterns in Hospitalizations for Malignant Spinal Cord Compression in the United States, 1998–2006

Cited by 106 publications

References 28 publications

Mortality and Longevity after a Spinal Cord Injury: Systematic Review and Meta-Analysis

Mortality and Longevity after a Spinal Cord Injury: Systematic Review and Meta-Analysis

Diagnosis and treatment of epidural metastases

Neurologic complications of lung cancer

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