Incidence and survival of symptomatic lacunar infarction in a Beijing population: a 6‐year prospective study

Abstract

LAC is a common stroke subtype in Northern China. Men or the elderly are more likely to have non-LAC. Long-term survival following LAC is similar to non-LAC patients.

Comparison of risk factors, severity and outcome between lacunar and non-lacunar stroke in a tertiary care center in Sri Lanka: A descriptive study

“…LAC stroke comprised 56.8% of ischaemic stroke included in our hospital based stroke registry. This finding is comparable to data from other Asian countries such as Japan and China [1,13]. Studies on stroke in European and North American countries show a higher non-LAC burden [1,14].…”

“…LAC are commoner in Asians and Japan reports a 50-60% incidence among ischaemic strokes compared to 16-38% in European and North American populations [1,13]. Reasons for this difference is not clear and the pattern in Sri Lanka is not known.…”

“…He proposed that lacunar strokes, asymptomatic small infarcts in striatocapsule are due to small vessel disease in the penetrating arteries and was the result of lipohyalinosis or atherosclerosis. Thus emerged the 'lacunar hypothesis' and these findings have led to studies on the two subtypes of stroke further enumerating that hypertension, diabetes and hyperlipidaemia are common in lacunar stroke with cardio embolism and large artery disease deemed less important [1,5]. But recent studies show that the risk factor profile is not different in stroke subtypes questioning the validity of lacunar hypothesis [6][7][8].…”

“…infarct size ≤ 2cm, b) anatomic site typical of LAC (basal ganglia, brainstem, thalamus, internal capsule or cerebral white matter) and c) compatible clinical presentation [1].…”

“…Prevalence of stroke is rising worldwide and is particularly common in South East Asia [1]. It is the fourth commonest cause for in-hospital mortality in Sri Lanka [2].…”