Incidence and survival of childhood leukemia in Recife, Brazil: A population‐based analysis

Lins, Mecneide Mendes; Santos, Marceli de Oliveira; Albuquerque, Maria de Fátima Pessoa Militão de; Castro, Claudia Cristina Lima de; Mello, Maria Júlia Gonçalves de; Camargo, Beatriz de

doi:10.1002/pbc.26391

Cited by 13 publications

(5 citation statements)

References 35 publications

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“…Survival rate in this study was lower than a study in Yogyakarta, where the survival rate of childhood with ALL was 56.1% [12]. In addition, there was a significant difference between ALL survival rates in this study and two studies conducted in Brazil and Germany [13], [14]. Survival rates of both studies are over 75%.…”

Section: Discussioncontrasting

confidence: 79%

Prognostic Factors and Survival Rate of Childhood Acute Lymphoblastic Leukemia in Eastern Indonesia: Kaplan–Meier and Cox Regression Approach

Arsunan

Elisafitri

Wahyu

et al. 2020

Open Access Maced J Med Sci

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BACKGROUND: Acute lymphoblastic leukemia (ALL) is one of the most common childhood hematological malignancies with an incident each year that tends to increase. AIM: This study aims to determine the survival rate of childhood ALL in Dr. Wahidin Sudirohusodo General Hospital and the prognostic factors that influence it. METHODS: A retrospective cohort design was conducted among childhood ALL. The samples were patients ALL diagnosed since January 1, 2014, until 31, 2017, in Dr. Wahidin Sudirohusodo General Hospital. A total of 109 patients were selected by simple random sampling. Data collected through medical records observations. Data were analyzed using Kaplan–Meier and Cox regression analysis. RESULTS: The cumulative survival rate of childhood ALL was 26%. The prognostic factors associated with survival of childhood ALL were nutritional status (p = 0.028), leukocyte counts (p = 0.000), platelet counts (p = 0.000), and comorbidity (p = 0.000). Based on multivariate analysis with Cox regression, the most influencing prognostic factor on survival of ALL patients was comorbidity (p = 0.000, hazard ratio = 3.699 confidence interval 95% 1.945–7.033). Childhood ALL with comorbidities had a risk of death 3699 times higher than childhood ALL without comorbidities. CONCLUSION: Nutritional status, leukocyte counts, platelet counts, and comorbidity were prognostic factors that influence survival of childhood ALL. Comorbidity was the most influencing prognostic factor on survival of childhood ALL.

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Section: Discussioncontrasting

confidence: 79%

Prognostic Factors and Survival Rate of Childhood Acute Lymphoblastic Leukemia in Eastern Indonesia: Kaplan–Meier and Cox Regression Approach

Arsunan

Elisafitri

Wahyu

et al. 2020

Open Access Maced J Med Sci

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“…In this study, although the mean value of total heath related QoL was relatively good and similar to the score of some developed countries, however we observed low mean value in perceived physical appearance subscales. We find some statistically significant effect when the total QoL compared with the social and medical characteristic of study group similar to study was done in Brazil, maybe due to good sample size (Lins et al, 2016).…”

Section: Discussionsupporting

confidence: 77%

Assessment of health-related quality of life of children and young adolescents with Cancer in National Cancer Institute in Sohag Governorate, Upper Egypt

Ali

Abd-Elrehim

2022

Journal of Environmental Studies

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The study objectives are to measure the quality of life among children with cancer compared to healthy peers and to determine factors affecting the QoL among those children. Analytic cross-sectional study was conducted in Sohag National Cancer Institute in Sohag Governorate for children with cancer and a comparison group of healthy peers. There were 3 tools were used for this study: Demographic questionnaire, Socio-economic scale, and Peds QL4.0 Generic Core Scale had to measure HRQoL. All items of QoL: physical, emotional, social, school, psychological and total QL scores were lower among the cancer patients group than the control group with very high statistically significant difference. The mean total QoL score was 70.9 ± 13.3 among the cancer group versus 94.2 ± 2.4 for the healthy peers. Males represented 47.1% of the studied group versus 52.9% for females. Other QoL functions showed no statistical significance difference regarding disease duration. Conclusions: cancer is negatively affecting all the QoL functioning of the children. We recommend that Integrated programs between child's home, school and National Cancer Institute for educating and supporting children with cancer to improve their HRQoL.

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“…Globally, the incidence of cancer in children differs from 48 to 70 per million children less than 15 years of age [3]. The incidence of childhood cancer in some developed countries, such as in United State, Ireland, Switzerland, and in Australia has reported with rates of 15.3, 13, 13.5, and 16 per 100,000 children, respectively, however in Asia the data are generally lower [4][5][6][7][8][9][10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Quality of Life in Pediatric Cancer Patients

Hegazy

Bar

Alamri

et al. 2019

JAMMR

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Background: In recent years the survival rates for children diagnosed with cancer has increased as result of successful treatment. Evaluation of health related quality of life during the process of treatments is important for recognition of acute dysfunction related to therapy and disease. Aim: Aim of the study is to identify the health-related quality of life in pediatric cancer patients and to detect the potential predictors of a total quality of life and its domains. Materials and Methods: It is a cross-sectional study done on convenient sample of pediatric cancer patients. Their diagnosis was confirmed at pediatric hematology clinic and day care unit at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. Results: A total number of 51 children participated in this study, their age ranging from 8-15 years with mean 10.15± 2.52. Hematological malignancies represented 70.5% of the sample, with the highest percentage for acute lymphocytic leukemia (45%). The mean value of the total quality of life is 73.48, which is referred to as a good quality of life. The best scores of subscales were cognitive problems (92.54), communication (82.67), and nausea (76.86), otherwise poorer score was detected. Although the value of total quality of life was relatively good however visiting the hospital more than 3 times per month, male gender, duration of therapy and duration of diagnosis more associated with more pain and hurt, great worry and treatment anxiety. Conclusion: Higher frequency of hospital visits, male gender, longer duration of diagnosis, longer duration of therapy, and increased intensity of therapy were all associated with more pain and hurt, great worry, nausea, and treatment anxiety which reflect a poor quality of life among the study group.

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Incidence and survival of childhood leukemia in Recife, Brazil: A population‐based analysis

Abstract: These data represent the incidence rate and survival of childhood leukemia in Recife, located in the northeast region of Brazil, using a high-quality database.

Cited by 13 publications

References 35 publications

Prognostic Factors and Survival Rate of Childhood Acute Lymphoblastic Leukemia in Eastern Indonesia: Kaplan–Meier and Cox Regression Approach

Prognostic Factors and Survival Rate of Childhood Acute Lymphoblastic Leukemia in Eastern Indonesia: Kaplan–Meier and Cox Regression Approach

Assessment of health-related quality of life of children and young adolescents with Cancer in National Cancer Institute in Sohag Governorate, Upper Egypt

Quality of Life in Pediatric Cancer Patients

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