ObjectiveLocal anesthetic solutions with vasoconstrictors are not contraindicated in
hypertensive patients, but due to their hemodynamic effects, local anesthetics
without vasoconstrictors are mainly preferred by the clinicians. The aim of this
study was to compare hemodynamic effects of three different local anesthetics
without vasoconstrictors during tooth extraction in hypertensive patients.Material and MethodsSixty-five mandibular molars and premolars were extracted in 60 hypertensive
patients (29 females and 31 males; mean age: 66.95 ± 10.87 years; range: 38
to 86 years old). Inferior alveolar and buccal nerve blocks were performed with 2%
lidocaine hydrochloride (HCl), 2% prilocaine HCl or 3% mepivacaine HCl without
vasoconstrictor. Hemodynamic parameters namely systolic blood pressure (SBP),
diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR),
saturation rate (SR), rate pressure product (RPP) and pressure rate quotient (PRQ)
were investigated before and at different intervals after anesthetic
injection.ResultsThe hemodynamic effects of the three agents were similar to each other, although
some significance was observed for DBP, MAP, RPP and PRQ values in the lidocaine,
prilocaine and mepivacaine groups.ConclusionLidocaine, prilocaine and mepivacaine solutions without vasoconstrictor can be
safely used in hypertensive patients. It is advisable that dental practitioners
select anesthetic solutions for hypertensive patients considering their
cardiovascular effects in order to provide patient comfort and safety.