Incidence and risk factors of aplastic anemia in Latin American countries: the LATIN case-control study

Maluf, Eliane Mara Cesário Pereira; Hamerschlak, Nelson; Cavalcanti, Alexandre Biasi; Avezum, Álvaro; Eluf-Neto, José; Falcão, Roberto Passetto; Lorand-Metze, Irene; Goldenberg, Daniel; Santana, Cézar Leite; Rodrigues, Daniela de Oliveira Werneck; Passos, Leny Nascimento da Motta; Rosenfeld, Luis Gastão Mange; Pitta, Marimilia; Loggetto, Sandra Regina; Ribeiro, Andreza Alice Feitosa; Velloso, Elvira Deolinda Rodrigues Pereira; Kondo, Andrea Tiemi; Coelho, Érika Oliveira de Miranda; Pintão, Maria Carolina; Souza, Hélio Moraes de; Borbolla, José R.; Pasqüini, Ricardo

doi:10.3324/haematol.2008.002642

Cited by 62 publications

(56 citation statements)

References 29 publications

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“…Certain hematological parameters were abnormal, namely hemoglobin which can lead to anemia. Similarly, lymphohema topoietic cancers was found among applicators [37], and aplastic anemia among farmers in Latin American countries [38].…”

Section: Discussionmentioning

confidence: 99%

Occupational Safety of Farmers in the Vegetable Industry

Lu¹

2011

International Journal of Occupational Safety and Ergonomics

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Section: Discussionmentioning

confidence: 99%

Occupational Safety of Farmers in the Vegetable Industry

Lu¹

2011

International Journal of Occupational Safety and Ergonomics

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“…Além disso, muitas vezes é utilizada para o alívio da dor, e figura entre os medicamentos mais prescritos na pediatria em diversos trabalhos nacionais, juntamente com o paracetamol e o ibuprofeno [1,29,30]. Esse fármaco é contraindicado em crianças com menos de três meses de idade e com menos de 5 kg [38], e apesar de possuir boa documentação para o uso pediátrico, sua segurança para essa população tem sido questionada em várias partes do mundo por possível associação com anemia aplásica e agranulocitose [31,39,40].…”

Section: Artigo Originalunclassified

Utilização de medicamentos em crianças internadas em um hospital geral

Martins

Uberti

Warpechowski

et al. 2017

Sci Med

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*** Medication use in children admitted to a general hospital ***AIMS: To describe the profile of medications used in children admitted to a general hospital.METHODS: A cross-sectional study was conducted with children aged 0 to 12 years, admitted to the Hospital Nossa Senhora da Conceição, in Tubarão, state of Santa Catarina, Brazil, between July 2013 and July 2014. The following data were collected: f age, sex, length of hospital stay, International Classification of Diseases codes for hospitalization, and medications used. The Anatomical Therapeutic Chemical classification system was used for the medications.RESULTS: The medical records of 1,603 children aged up to 12 years were analyzed. The hospital stay ranged from one to 115 days. The number of medications per admission ranged from one to 77, with an average of 9.84 medications per patient. A total of 211 different types of medications were used, most of which were classified as analgesic with central nervous system activity. Tonsillar hypertrophy and adenoid hypertrophy were the most prevalent disorders diagnosed among the 303 different International Classification of Diseases codes found in this study. Seven types of unlicensed medications and 23 drugs with some kind of restriction for pediatric use were prescribed.CONCLUSIONS: The average number of medications was high in hospitalized children, and the prescription of unlicensed drugs and those with some kind of restriction for pediatric use was an important factor. These data suggest poor attention to the risks and benefits of medication use in children – a relevant issue that requires continuous and intensive surveillance by different health professionals .

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“…These initial observations of higher rates in Asia compared with elsewhere appear to be valid when reviewing studies from different countries. Studies in Latin America [5], France [6], Turkey [7], Brazil [8], and Barcelona [9] have reported rates of 1.6, 1.5, 0.64, 2.4, and 2.5 per million, respectively, compared with 3.9 and 4.8 per million for Thailand [10] and Sabah [11] in Malaysia.…”

Section: Introductionmentioning

confidence: 99%