Incidence and risk factors of urinary tract infection in very low birth weight infants

Ruangkit, Chayatat; Satpute, Ankita; Vogt, Beth A.; Hoyen, Claudia K.; Viswanathan, S.

doi:10.3233/npm-16915055

Cited by 22 publications

(24 citation statements)

References 26 publications

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“…Urinary tract infections are uncommon in the first 72 hours of life. Urine cultures are therefore only performed in the evaluation of LONS [35]. Lumbar puncture (LP) should be routinely performed in neonates showing signs of EONS or LONS.…”

Section: Diagnostic Testingmentioning

confidence: 99%

Neonatal Sepsis

Ershad

Mostafa

Cruz

et al. 2019

Curr Emerg Hosp Med Rep

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Section: Diagnostic Testingmentioning

confidence: 99%

Neonatal Sepsis

Ershad

Mostafa

Cruz

et al. 2019

Curr Emerg Hosp Med Rep

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“…The ability to identify patients in the neonatal intensive care unit who are at increased risk for UTI would help ensure that those patients have urine cultures [11]. In the very low-birth-weight neonates, UTI was associated with higher cholestasis, higher central line and parenteral nutrition days, prolonged mechanical ventilation, and chronic lung disease [12]. Yet, it is unclear whether these risk factors are the same for full-term neonates.…”

Section: Introductionmentioning

confidence: 99%

Prevalence and predictors of urinary tract infection in full-term and preterm neonates

Mohamed

Bassyouni

Mahmoud

2020

Egypt Pediatric Association Gaz

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Background: Early and prompt diagnosis of urinary tract infection (UTI) in neonates has important therapeutic implications. The aim of this study was to evaluate the prevalence of UTI in neonates admitted to a referral neonatal intensive care unit (NICU) and to identify predictors associated with an increased risk of UTI in NICU population. Results: The prevalence of culture-proven UTI in the studied neonates was 6.67%. Moreover, UTI was more frequent (70%) among full-term neonates. Additionally, both fever and pyuria were the only clinical and laboratory findings that showed significant association with UTI (p < 0.05). Binary logistic regression revealed that neonates with pyuria in urine analysis were 5.44 times more liable to have UTI, while the presence of fever constitutes a risk of only 0.166 (odds ratios were 5.44 and 0.166, respectively). Additionally, sensitivity, specificity, positive predictive value, and negative predictive value of the regression model were 50.0, 94.5, 20.05, and 98.57%, respectively. Conclusions: We conclude that UTI is not uncommon in full-term neonates admitted in NICU. Additionally, pyuria was significantly related to positive urine culture and its detection in urine analysis increases the likelihood of UTI by 5.44 times.

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“…A recent study also found a low incidence of urinary tract abnormalities and VUR in a cohort of very low birth weight infants. 16 The AAP guidelines for diagnosis and management of UTI only apply to infants age 2–24 months, and do not apply to hospitalized infants in the NICU. 1 To our knowledge, there are no formal guidelines on diagnosis and management of UTI in patients admitted to the NICU, namely premature infants and infants less than 2 months of age.…”

Section: Discussionmentioning

confidence: 99%