Incidence and Risk Factors of Postoperative Delirium in Patients with Esophageal Cancer

Takeuchi, Mika; Takeuchi, Hiroya; Fujisawa, Daisuke; Miyajima, Ken; Yoshimura, Kimio; Hashiguchi, Saori; Ozawa, Soji; Ando, Nobutoshi; Shirahase, Joichiro; Kitagawa, Yuko; Mimura, Masaru

doi:10.1245/s10434-012-2432-1

Cited by 94 publications

(88 citation statements)

References 25 publications

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“…Their results are similar to ours 11% (6/59); however, they did not investigate the chronological change of cognition or perceptual disturbance of the patients after surgery. Compared to previous studies of other surgical procedures, postoperative delirium developed in 50.0% (153/306) of patients who had undergone an esophagectomy [25], in 10.9% (14/129) of elderly patients (>70 years old) undergoing surgery for colorectal cancer [26], and in 11.7% (47/401) of elderly patients who underwent hepatectomy [27]. The occurrence rate of postoperative delirium varied based on the surgical procedures; however, postoperative delirium developed especially in more than 10% of elderly patients.…”

Section: Discussioncontrasting

confidence: 59%

“…Old age has been well known and focused on as a risk factor of postoperative delirium in patients who underwent PD [24], esophagectomy [25], and surgery for abdominal aortic aneurysm or colorectal cancer [33], because of increasing the population of aged people who need to undergo abdominal surgery. In aged patients, preexisting cognitive dysfunction including dementia was reported as the strongest predictor of the development of postoperative delirium [34].…”

Section: Discussionmentioning

confidence: 99%

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Incidence and Risk Factors of Postoperative Delirium following Pancreatic Surgery: Does the Administration of TJ-54 Reduce the Incidence of Delirium

Mizuno

Takeuchi²,

Kishiwada

et al. 2017

Dig Surg

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Purposes: To clarify the incidence and risk factors of postoperative delirium in patients following pancreatic surgery, and the impact of yokukansan (TJ-54) administered to reduce delirium. Methods: Fifty-nine consecutive patients who underwent pancreatic surgery (2012.4-2013.5) were divided into 2 groups: TJ-54 group: patients who received TJ-54 (n = 21) due to insomnia and the No-TJ-54 group: patients who did not receive TJ-54 (n = 38), and the medical records including the delirium rating scale - Japanese version (DRS-J) were retrospectively reviewed. Results: Postoperative delirium occurred in 2 patients (9.5%) in the TJ-54 group and in 4 (10.5%) patients in the No-TJ-54 group (p = 0.90). The DRS-J on 5 days after surgery was lower in the TJ-54 group than in the No-TJ-54 group (rough p = 0.006), however, without any statistically significant differences with the Bonferroni correction. As for the hospital cost, there was no difference between the TJ-54 and the No-TJ-54 groups (p = 0.78). History of delirium was identified as an independent risk factor of postoperative delirium. Conclusion: The patients with preoperative insomnia, who were treated with TJ-54, did not have a higher incidence of postoperative delirium, compared to those without preoperative insomnia. The patients who had a history of delirium have an increased risk of postoperative delirium and should be cared for and treated prophylactically to prevent it.

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Section: Discussioncontrasting

confidence: 59%

Section: Discussionmentioning

confidence: 99%

Incidence and Risk Factors of Postoperative Delirium following Pancreatic Surgery: Does the Administration of TJ-54 Reduce the Incidence of Delirium

Mizuno

Takeuchi²,

Kishiwada

et al. 2017

Dig Surg

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“…Delirium is not a disease, but rather a clinical syndrome. It is defined as a change in mental status and is characterized by a disturbance in consciousness with a reduced ability to focus and changes in cognitive functions (1). Delirium is also encompassing other neuropsychiatric symptoms, including disorientation, thought disorder, memory problems, language disorder, sleep disturbance, delusions, mood lability and so on.…”

Section: Introductionmentioning

confidence: 99%

Risk factors for postoperative delirium in patients undergoing major head and neck cancer surgery: a meta-analysis

Zhu

Wang

Liu

et al. 2017

Japanese Journal of Clinical Oncology

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Objective: Postoperative delirium is common after extensive surgery. This study aimed to collate and synthesize published literature on risk factors for delirium in patients with head and neck cancer surgery. Methods: Three databases were searched (MEDLINE, Embase, and Cochrane Library) between January 1987 and July 2016. The Newcastle Ottawa Scale (NOS) was adopted to evaluate the study quality. Pooled odds ratios or mean differences for individual risk factors were estimated using the Mantel-Haenszel and inverse-variance methods. Results: They provided a total of 1940 patients (286 with delirium and 1654 without), and predominantly included patients undergoing head and neck cancer surgery. The incidence of postoperative delirium ranged from 11.50% to 36.11%. Ten statistically significant risk factors were identified in pooled analysis. Old age, age >70 years, male sex, duration of surgery, history of hypertension, blood transfusions, tracheotomy, American Society of Anesthesiologists physical status grade at least III, flap reconstruction and neck dissection were more likely to sustain delirium after head and neck cancer surgery. Conclusion: Delirium is common in patients undergoing major head neck cancer surgery. Several risk factors were consistently associated with postoperative delirium. These factors help to highlight patients at risk of developing delirium and are suitable for preventive action.

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“…Surgery is the most effective treatment for colorectal cancer, but it tends to be associated with higher morbidity and mortality rates in this age group than in younger age groups. In particular, the incidence of postoperative delirium (POD) is relatively high in elderly patients; reported rates range from 28 to 50 % among hospitalized patients with cancer [1][2][3][4] and are thought to correlate with various perioperative clinical variables in cardiac, general, and vascular diseases [5][6][7]. Therefore, the strategies required to reduce the incidence of POD may vary according to the risk level and type of underlying disease.…”

Section: Introductionmentioning

confidence: 99%

Incidence and risk factors of postoperative delirium in elderly patients who underwent laparoscopic surgery for colorectal cancer

Tei

Wakasugi

Kutsukake

et al. 2015

Int J Colorectal Dis

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Incidence and Risk Factors of Postoperative Delirium in Patients with Esophageal Cancer

Cited by 94 publications

References 25 publications

Incidence and Risk Factors of Postoperative Delirium following Pancreatic Surgery: Does the Administration of TJ-54 Reduce the Incidence of Delirium

Incidence and Risk Factors of Postoperative Delirium following Pancreatic Surgery: Does the Administration of TJ-54 Reduce the Incidence of Delirium

Risk factors for postoperative delirium in patients undergoing major head and neck cancer surgery: a meta-analysis

Incidence and risk factors of postoperative delirium in elderly patients who underwent laparoscopic surgery for colorectal cancer

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