Incidence and risk factors for ventilator-associated pneumonia after major heart surgery

Abstract

VAP is common in patients undergoing MHS that require more than 48 h of MV. In that "high-risk" population, innovative preventive measures should be developed and applied.

Ventilator-associated pneumonia is an important risk factor for mortality after major cardiac surgery

“…Overall in-hospital mortality in the study population was 6.9%, with a mortality rate in patients with VAP of 45.7% vs 2.8% in patients without VAP (P ≤ .001). However, in a recent European multicenter study [40], a VAP incidence rate of 2.2%, lower than that found in our and other studies [3,38,39], was identified.…”

Ventilator-Associated Pneumonia Is an Important Risk Factor for Mortality After Major Cardiac Surgery

“…This study did not analyze the impact of such variables on the mortality rate of VAP simply because it was not the aim of this work. However, the study data referring to the average time before VAP commences (5.5 days), appropriate antibiotic therapy (64%), presence of bacteremia (44.8%), and the distribution of common isolated pathogens in cultures are in accordance with those found in other studies [3,16,18,23,38,39].…”

“…Death was significantly more frequent in patients with VAP (57.1%) than in any other group. In a study of 1844 patients, Hortal et al [39] found that the cumulative incidence of VAP during the study period was 5.7%. Overall in-hospital mortality in the study population was 6.9%, with a mortality rate in patients with VAP of 45.7% vs 2.8% in patients without VAP (P ≤ .001).…”

Effect of Oral Hygiene and 0.12% Chlorhexidine Gluconate Oral Rinse in Preventing Ventilator-Associated Pneumonia After Cardiovascular Surgery

“…1,4 It is therefore essential to further efforts to prevent VAP and to identify predisposing risk factors to control them. 5 The patient's own flora is a primary source of microorganisms for the development of this pathology. Aspiration of microorganisms from the aerodigestive tract has been involved in the physiopathology of VAP and is the most important risk factor for colonization of the oropharynx.…”