Incidence and Risk Factors for Systemic Infection in Deceased Donors

Dinçer, Pelin Çorman; Altun, Gülbin Töre; Birtan, Deniz; Arslantaş, Reyhan; Mert, Nurcan Sarici; Özdemir, Ihsan; Arslantaş, Mustafa Kemal

doi:10.1016/j.transproceed.2019.03.054

Cited by 6 publications

(4 citation statements)

References 6 publications

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“…What we do know is that donor ICU LOS is correlated directly with a higher risk of infection in those donors with cut‐offs set between 3 and 5 days 14,15 16 …”

Section: Introductionmentioning

confidence: 99%

Impact of length of donor ICU stay on outcome of patients after pediatric liver transplantation with whole and in situ split liver grafts

Misar

Mclin

Calinescu

et al. 2021

Pediatric Transplantation

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Background Patients who have a prolonged stay in the intensive care unit (ICU) are often excluded for organ donation because of supposed deleterious effects of a lengthy ICU stay. We aimed to determine the effects of a prolonged donor stay in the ICU on the outcome of liver transplantation (LT) in children. Methods Retrospective review of 89 pediatric LT patients, age 0–18 years, period 2003–2018, including patients having undergone whole organ or in situ split LT. The patients were divided into two groups according to the donor length of stay in the ICU. A prolonged stay was defined as >5 days. Recipient, graft, and donor characteristics were compared; outcome parameters included recipient and graft survival rates and postoperative complications. Results Group short (donor ICU stay <5 days) included 75 patients, group long (donor ICU stay >5 days) 14 patients. Baseline characteristics between recipients did not differ. Donors in group long had significantly more infectious complications and a higher gamma glutamyl transferase (gGT) the day of organ recovery. Incidence of biliary complications post‐LT was significantly higher in group long (p = .029). Patient and graft survival rates did not differ significantly between groups. Conclusions Donors with a prolonged stay in the ICU should still be considered for liver donation if they fulfill most other selection criteria. Recipients from donors having stayed in ICU >5 days may be at increased risk of biliary complications.

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“…What we do know is that donor ICU LOS is correlated directly with a higher risk of infection in those donors with cut‐offs set between 3 and 5 days 14,15 16 …”

Section: Introductionmentioning

confidence: 99%

Impact of length of donor ICU stay on outcome of patients after pediatric liver transplantation with whole and in situ split liver grafts

Misar

Mclin

Calinescu

et al. 2021

Pediatric Transplantation

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show abstract

“…At present, many medical workers attach great importance to hospital infection which was one of the common complications in hospital, thus the prevention and control of hospital infection was one of the crucial tasks of the whole medical staff of hospital. Compared with the nurses in the other departments, the work of nurses in the operating room was busy and complex, which can easily lead to the occurrence of hospital infection 20 . Therefore, it is always necessary to carry out anti‐infection management for nurses in operating room.…”

Section: Discussionmentioning

confidence: 99%

“…Compared with the nurses in the other departments, the work of nurses in the operating room was busy and complex, which can easily lead to the occurrence of hospital infection. 20 Therefore, it is always necessary to carry out anti-infection management for nurses in operating room. Strict anti-infection measures in the operating room can not only reduce the waste of social resources, but also alleviate the economic burden of patients.…”

Section: Discussionmentioning

confidence: 99%

Effects of perioperative comprehensive nursing based on risk prevention for patients with intracranial aneurysm

Wang

Zhao

2020

Int J Clin Pract

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Objective To explore the effect of comprehensive nursing based on risk prevention in perioperative nursing of intracranial aneurysm. Methods A total of 156 patients who suffered from intracranial aneurysm were admitted in neurosurgery department from the hospital between January 2018 and January 2019. Patients were randomly divided into observation group (n = 78, patients were given comprehensive nursing based on risk prevention) and control group (n = 78, patients were given routine nursing). The following parameters, such as postoperative hospital stay, rescue success rate, Glasgow coma scale (GCS) after being awake, anxiety degree and nursing effect (incidence of complications, incidence of infection and patient satisfaction) were compared between the two groups. Results The postoperative hospital stay, rescue success rate and GCS after intervention in the observation group were significantly better than those in the control group (P < .05). The degree of anxiety in the observation group after intervention was superior to that in the control group (P < .05), similar results were obtained in terms of the nursing effect in the observation group compared with the control group (P < .05). Conclusion Comprehensive nursing was associated with the shortness of hospitalisation time of patients, improved rescue rate, reduced occurrence of complications and infection, and improved satisfaction of patients. Thus, comprehensive nursing was regarded to exert protective effect with a promising future for clinical practice.

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“…Infection in donors is not a rare condition, and it is found in about 20% of donors. 13 It was found that bacteremia was detected in about 5% of deceased donors, 10 and Candida species were detected in preservation fluid in about 0.1% of cases. 14 Even if there is an active or suspected infection in the donor, it is recommended to consider the use of allograft based upon the urgency of transplantation for the recipient, the availability of alternative organs, and recipient informed consent.…”

Section: Discussionmentioning

confidence: 97%

Kidney Transplantation From Deceased Donors With Bloodstream Infection: A Multicenter Retrospective Study

Lee

Park

et al. 2022

J Korean Med Sci

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Background The use of organs from donors with infection is limited because of the possibility of transmission. We aimed to investigate the transmission after deceased donor transplantation with bloodstream infection (BSI). Methods A retrospective study of patients undergoing kidney or pancreas transplantation at five tertiary centers in Korea from January 2009 and November 2019 was performed. We analyzed the outcomes after transplantation from deceased donors with BSI. Results Eighty-six recipients received transplantation from 69 donors with BSI. The most common isolated pathogens from donors were Gram-positive bacteria (72.0%), followed by Gram-negative bacteria (22.7%), and fungi (5.3%). Appropriate antimicrobial agents were used in 47.8% of donors before transplantation. Transmission occurred only in 1 of 83 recipients (1.2%) from bacteremic donors and 1 of 6 recipients (16.7%) from fungemic donors. One-year patient and graft survival was 97.5%and 96.3%, respectively. There was no significant difference in graft and patient survival between patients who received organs from infected donors and noninfected donors. Conclusion Using organs from donors with bacteremia seems to be a safe option with low transmission risk. The overall prognosis of using organs from donors with BSI is favorable.

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Incidence and Risk Factors for Systemic Infection in Deceased Donors

Cited by 6 publications

References 6 publications

Impact of length of donor ICU stay on outcome of patients after pediatric liver transplantation with whole and in situ split liver grafts

Impact of length of donor ICU stay on outcome of patients after pediatric liver transplantation with whole and in situ split liver grafts

Effects of perioperative comprehensive nursing based on risk prevention for patients with intracranial aneurysm

Kidney Transplantation From Deceased Donors With Bloodstream Infection: A Multicenter Retrospective Study

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