Incidence and risk factors for new-onset atrial fibrillation following coronary artery bypass grafting: A systematic review and meta-analysis

Higgs, Megan; Sim, Jenny; Traynor, Victoria

doi:10.1016/j.iccn.2020.102897

Cited by 11 publications

(27 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…They should also have knowledge of the other risk factors for new-onset of POAF after CABG, which are high preoperative serum creatinine and low hemoglobin level, low LVEF, essential hypertension, COPD, and preexisting renal failure, long CPB time, postoperative use of inotropes, postoperative renal failure, and re-operation. These risk factors identified in our review agree with previous results [ 4 , 34 , 35 ], presenting clear evidence of their importance. Based on these findings, it may be effective to design strategies for the timely screening of patients who are at high risk of new-onset POAF after CABG to provide patient-centered care according to their clinical trajectory.…”

Section: Discussionsupporting

confidence: 93%

“…The following predisposing factors for POAF after CABG have previously been identified: advanced age, obesity, and comorbidities, such as hypertension, diabetes mellitus, and chronic obstructive pulmonary disease (COPD) [ 4 , 7 , 13 , 14 ]. However, the risk factors for new-onset POAF after CABG remain inconclusive.…”

Section: Introductionmentioning

confidence: 99%

“…Systematic reviews regarding the relationship between POAF and adverse outcomes after CABG have largely focused on mortality [ 8 , 12 , 15 ]. One systematic review which did seek to identify risk factors for POAF after CABG included studies for only on-pump CABG with all types of cohort study designs [ 4 ]. The impact of cardiopulmonary bypass (CPB) on the clinical outcomes of CABG, including POAF, is still being debated [ 16 ].…”

Section: Introductionmentioning

confidence: 99%

“…Coronary artery bypass grafting (CABG) is the standard of care for the treatment of advanced coronary artery disease [1,2]. Despite its value, CABG is associated with a high risk of postoperative cardiac and non-cardiac complications, including dysrhythmia, the need for reoperation, cognitive decline, and mortality [3][4][5]. Newonset postoperative atrial fibrillation (POAF) is the most common cardiac dysrhythmia to occur after CABG [6,7].…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Perioperative risk factors for new-onset postoperative atrial fibrillation after coronary artery bypass grafting: a systematic review

Seo

Hong

Lee

et al. 2021

BMC Cardiovasc Disord

View full text Add to dashboard Cite

Background Postoperative atrial fibrillation (POAF) is the most common cardiac dysrhythmia to occur after coronary artery bypass grafting (CABG). However, the risk factors for new-onset POAF after CABG during the perioperative period have yet to be clearly defined. Accordingly, the aim of our systematic review was to evaluate the perioperative predictors of new-onset POAF after isolated CABG. Method Our review methods adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline. We searched seven electronic databases (PubMed, Embase, CINAHL, PsycArticles, Cochrane, Web of Science, and SCOPUS) to identify all relevant English articles published up to January 2020. Identified studies were screened independently by two researchers for selection, according to predefined criteria. The Newcastle–Ottawa Scale was used to evaluate the quality of studies retained. Results After screening, nine studies were retained for analysis, including 4798 patients, of whom 1555 (32.4%) experienced new-onset POAF after CABG. The incidence rate of new-onset POAF ranged between 17.3% and 47.4%. The following risk factors were identified: old age (p < 0.001), a high preoperative serum creatinine level (p = 0.001), a low preoperative hemoglobin level (p = 0.007), a low left ventricle ejection fraction in Asian patients (p = 0.001), essential hypertension (p < 0.001), chronic obstructive pulmonary disease (p = 0.010), renal failure (p = 0.009), cardiopulmonary bypass use (p = 0.002), perfusion time (p = 0.017), postoperative use of inotropes (p < 0.001), postoperative renal failure (p = 0.001), and re-operation (p = 0.005). All studies included in the analysis were of good quality. Conclusions The risk factors identified in our review could be used to improve monitoring of at-risk patients for early detection and treatment of new-onset POAF after CABG, reducing the risk of other complications and negative clinical outcomes.

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Perioperative risk factors for new-onset postoperative atrial fibrillation after coronary artery bypass grafting: a systematic review

Seo

Hong

Lee

et al. 2021

BMC Cardiovasc Disord

View full text Add to dashboard Cite

show abstract

“…Nevertheless, whether obesity independently increases the risk of POAF is still unclear according to meta-analyses. For example, in an excellent comprehensive review involving 62,160 individuals and 16,768 cases (Wong et al, 2015a), BMI was found to be an independent risk factor for POAF; however, the same result for BMI was not found by recent meta-analysis (Yamashita et al, 2019) or literature reviews (Higgs, Sim & Traynor, 2020). Third, to date, no comprehensive study has quantitatively assessed the exposure-effect relationship between BMI and POAF.…”

Section: Introductionmentioning

confidence: 98%

Dose-response relationship among body mass index, abdominal adiposity and atrial fibrillation in patients undergoing cardiac surgery: a meta-analysis of 35 cohorts

Liu

Mei

Xie

et al. 2021

PeerJ

View full text Add to dashboard Cite

Background Whether overweight increases the risk of postoperative atrial fibrillation (POAF) is unclear, and whether adiposity independently contributes to POAF has not been comprehensively studied. Thus, we conducted a meta-analysis to clarify the strength and shape of the exposure-effect relationship between adiposity and POAF. Methods The PubMed, Cochrane Library, and EMBASE databases were searched for revelant studies (randomized controlled trials (RCTs), cohort studies, and nest-case control studies) reporting data regarding the relationship between adiposity and the risk of POAF. Results Thirty-five publications involving 33,271 cases/141,442 patients were included. Analysis of categorical variables showed that obesity (RR: 1.39, 95% CI [1.21–1.61]; P < 0.001), but not being underweight (RR: 1.44, 95% CI [0.90–2.30]; P = 0.13) or being overweight (RR: 1.03, 95% CI [0.95–1.11]; P = 0.48) was associated with an increased risk of POAF. In the exposure-effect analysis (BMI) was 1.09 (95% CI [1.05–1.12]; P < 0.001) for the risk of POAF. There was a significant linear relationship between BMI and POAF (Pnonlinearity = 0.44); the curve was flat and began to rise steeply at a BMI of approximately 30. Notably, BMI levels below 30 (overweight) were not associated with a higher risk of POAF. Additionally, waist obesity or visceral adiposity index was associated with the risk of POAF. Conclusion Based on the current evidence, our findings showed that high body mass index or abdominal adiposity was independently associated with an increased risk of POAF, while underweight or overweight might not significantly increase the POAF risk.

show abstract

Are CHADS2 and CHA 2DS 2-VASc of value in risk assessment for new-onset post-operative atrial fibrillation?

Smet

Potter

Heggermont

2020

Intensive and Critical Care Nursing

View full text Add to dashboard Cite

Incidence and risk factors for new-onset atrial fibrillation following coronary artery bypass grafting: A systematic review and meta-analysis

Cited by 11 publications

References 18 publications

Perioperative risk factors for new-onset postoperative atrial fibrillation after coronary artery bypass grafting: a systematic review

Perioperative risk factors for new-onset postoperative atrial fibrillation after coronary artery bypass grafting: a systematic review

Dose-response relationship among body mass index, abdominal adiposity and atrial fibrillation in patients undergoing cardiac surgery: a meta-analysis of 35 cohorts

Are CHADS2 and CHA 2DS 2-VASc of value in risk assessment for new-onset post-operative atrial fibrillation?

Contact Info

Product

Resources

About