Incidence and risk factors for norovirus‐related diarrhea in Japanese geriatric intermediate care facilities: A prospective cohort study

Suita, Asae; Ohfuji, Satoko; Fukushima, Wakaba; Ito, Kazuya; Kase, Tetsuo; Kondo, Kyoko; Ishibashi, Masayoshi; Kumashiro, Hiroko; Kawai, Shuji; Deguchi, Akifumi; Nakata, Hajime; Iba, Kazuko; Kita, Tetsuya; Kinugawa, Kazuhiko; Hamada, Kaoru; Fujimoto, Mikio; Furukawa, Yoichi; Sowa, Etsuji; Nakazawa, Hideo; Hirota, Yoshio

doi:10.1111/ggi.14539

Cited by 4 publications

(2 citation statements)

References 23 publications

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“…Cognitive function was assessed using the “dementia rating,” 19 which is widely used in the Japanese LTC insurance system and was used in a previous study 20 . This tool assessed cognitive function using five classifications: (i) almost independent, (ii) independent if someone will look after them, (iii) mild cognitive impairment, (iv) moderate cognitive impairment, and (v) severe cognitive impairment.…”

Section: Methodsmentioning

confidence: 99%

Physical function decline predictors in nursing home residents using new national quality indicators

Noguchi‐Watanabe,

Ishikawa,

Ikuta

et al. 2023

Geriatrics Gerontology Int

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AimTo determine the predictors of physical function (PF) decline among nursing home residents using items from the Long‐term care Information system For Evidence (LIFE), a system launched in 2021 to ensure the quality of long‐term care.MethodsThe LIFE data of 1648 residents from 45 nursing homes in Japan were retrospectively collected in July 2021 (T0) and January 2022 (T1), including demographics, PF assessed by the Barthel index (BI), nutrition and oral health, and cognitive function. The Dementia Behavior Disturbance scale was used to assess the frequency of certain behaviors, such as “waking at midnight.” The predictors of PF decline, defined as a decrease ≥5 in the BI score at T1 compared with that at T0, were determined using mixed‐effects logistic regression analyses. PF at T0 was classified into high (>60 BI) and low (≤60 BI) groups.ResultsThe participants' mean age was 87.2 ± 7.1 years, and 45.3% experienced PF decline. The significant predictors of PF decline were age ≥ 90 years, body mass index <18.5 kg/m2, dementia diagnosis, moderate and severe cognitive impairments, not vocalizing reciprocal exchanges at will, always “waking at midnight,” and high PF at T0.ConclusionsThe LIFE items predicted PF decline among nursing home residents, suggesting that LIFE data can be used to ensure the quality of long‐term care. Geriatr Gerontol Int 2023; ••: ••–••.

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Section: Methodsmentioning

confidence: 99%

Physical function decline predictors in nursing home residents using new national quality indicators

Noguchi‐Watanabe,

Ishikawa,

Ikuta

et al. 2023

Geriatrics Gerontology Int

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“…Viral infectious diseases, such as coronavirus disease 2019 [1][2][3], influenza [4][5][6] and norovirus gastroenteritis [7,8], are major domestic public health concerns. These diseases are highly contagious, which makes the inactivation of these viruses a matter of utmost priority in preventing the spread of infections.…”

Section: Introductionmentioning

confidence: 99%

pH-dependent virucidal effects of weak acids against pathogenic viruses

Hu,

Shimoda,

Tsuchiya

et al. 2024

Trop Med Health

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Background Weak acids, such as acetic acid, show virucidal effects against viruses, and disinfectants are considered effective virucidal agents possibly because of their low pH, depending on the proton concentration. This study aimed to evaluate the efficacy of different weak acids (acetic, oxalic, and citric acids) and eligible vinegars under different pH conditions by comparing their inactivation efficacies against enveloped and non-enveloped viruses. Methods Acetic, oxalic, and citric acids were adjusted to pH values of 2, 4 and 6, respectively. They were also diluted from 1 M to 0.001 M with distilled water. Enveloped influenza A virus (FulV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and non-enveloped feline calicivirus (FCV) were treated with adjusted weak acids for up to 30 min. These viruses were also reacted with white distilled vinegar (WDV) and grain-flavored distilled vinegar (GV) for up to 30 min. Infectious viral titers after the reactions were expressed as plaque-forming units per mL. Results Acetic acid showed virucidal effects against FulV at pH 4, whereas citric and oxalic acids did not. Acetic and citric acids inactivated SARS-CoV-2 at pH 2, whereas oxalic acid did not. All acids showed virucidal effects against FVC at pH 2; however, not at pH 4. The virucidal effects of the serially diluted weak acids were also reflected in the pH-dependent results. WDV and GV significantly reduced FulV titers after 1 min. SARS-CoV-2 was also susceptible to the virucidal effects of WDV and GV; however, the incubation period was extended to 30 min. In contrast, WDV and GV did not significantly inactivate FCV. Conclusions The inactivation efficacy of weak acids is different even under the same pH conditions, suggesting that the virucidal effect of weak acids is not simply determined by pH, but that additional factors may also influence these effects. Moreover, eligible vinegars, the main component of which is acetic acid, may be potential sanitizers for some enveloped viruses, such as FulV, in the domestic environment.

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Prevalence and associated factors of norovirus infections among patients with diarrhea in the Amhara national regional state, Ethiopia

Tegegne,

Gelaw,

Zerefaw

et al. 2024

BMC Infect Dis

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Incidence and risk factors for norovirus‐related diarrhea in Japanese geriatric intermediate care facilities: A prospective cohort study

Cited by 4 publications

References 23 publications

Physical function decline predictors in nursing home residents using new national quality indicators

Physical function decline predictors in nursing home residents using new national quality indicators

pH-dependent virucidal effects of weak acids against pathogenic viruses

Prevalence and associated factors of norovirus infections among patients with diarrhea in the Amhara national regional state, Ethiopia

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