Incidence and risk factors for neonatal hypoglycaemia in Kerala, India

Sasidharan, C. K.; Gokul, E; Sabitha, Sasidharanpillai

doi:10.4038/cmj.v49i4.1919

Cited by 32 publications

(51 citation statements)

References 13 publications

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“…In addition to this they found that breast feeding delay of greater than 2 hours and maternal oligihydraminos after delivery considerably increases the risk of neonatal hypoglycemia. 13 The overall incidence of asymptomatic hypoglycemia was in the present study was found to be 20%. Diwakar et al in their study of healthy term infants found out the incidence to be 14%.…”

Section: Discussionsupporting

confidence: 46%

The incidence of asymptomatic hypoglycemia in term newborn babies weighing more than two kilograms

Thirumalaikumarasamy

Ramalingam

Moorthi

et al. 2017

Int J Contemp Pediatr

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Background: Neonatal hypoglycemia is a common metabolic problem especially in cases like prematurity, sepsis and small gestational age. Episodes of asymptomatic hypoglycemia may occur due to many risk factors. The present study aimed to evaluate the incidence of asymptomatic hypoglycemia in term new born babies weighing more than 2 kg, to study the plasma sugar level at various time points during first 48 hours of life and to study the effect of maternal factors like parity, mode of delivery, glucose infusion during labour, and time since last feed on plasma sugar level.Methods: A hospital based longitudinal study was conducted over a period of one year from April 2005 to March 2006 in Kilpauk Medical College Hospital, Chennai. 400 babies born of consecutive deliveries were included in the study. Their plasma glucose levels were assessed in cord blood, 3 hr, 12 hr and 36 hr of life. Plasma glucose levels were analysed with regards to distribution, variables like parity, mode of delivery, dextrose infusion during labour and time since last feed. The plasma glucose levels were statistically analysed by paired student ‘t’ test, multiple analysis of variance (ANOVA), chi- square test using SPSS (version 7.5) statistical package.Results: The overall incidence of hypoglycemia was seen in 20% of the neonate’s in which 29.7% in small gestational age (SGA) and 16.7% in appropriate gestational age (AGA) babies. A significant (p <0.01) association between hypoglycemia and birth weight was observed. The association between hypoglycemia with parity, mode of delivery, sex of the baby and glucose infusion received by the mother was studied, but no significant association was found. A significant difference in plasma glucose based on birth weight at 3rd hour, 12th hour and 36th hour was observed (p <0.05). None of the infants showed any clinical signs of hypoglycemia.Conclusions: The incidence of hypoglycemia was noted in 20% of the neonates. Low birth weight was considered as risk factor. A significant association was also observed between plasma glucose, mode of delivery and time since last fed.

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Section: Discussionsupporting

confidence: 46%

The incidence of asymptomatic hypoglycemia in term newborn babies weighing more than two kilograms

Thirumalaikumarasamy

Ramalingam

Moorthi

et al. 2017

Int J Contemp Pediatr

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“…Preterm infants are especially vulnerable. Hypothermia is also associated with serious morbidities, such as increased risk of IVH, 19,26,39,[50][51][52][53][54] respiratory issues, 15,19,21,50,[55][56][57][58][59][60] hypoglycemia, 15,44,[60][61][62][63][64] and late-onset sepsis. 33,65 Because of this, admission temperature should be recorded as a predictor of outcomes as well as a quality indicator (Class I, LOE B-NR.)…”

Section: Importance Of Maintaining Normal Temperature In the Deliverymentioning

confidence: 99%

Part 13: Neonatal Resuscitation

Wyckoff¹,

Aziz²,

Escobedo³

et al. 2015

Circulation

609

344

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“…43,60 For the serious outcome of hypoglycemia, there were seven observational studies (very-low-quality, downgraded for risk of bias and indirectness) showing a significant association between hypothermia (less than 36°C) and hypoglycemia. 44,67,70,[97][98][99][100] Two of these studies, using historical controls, showed improved glycemic control with improved normothermia. 44,99 For the serious outcome of late sepsis, 2 observational studies (very-lowquality evidence, downgraded for risk of bias and indirectness) indicated an association between hypothermia on admission and late sepsis.…”

Section: Consensus On Sciencementioning

confidence: 99%