Incidence and Prognostic Implications of Diplopia in Patients with Giant Cell Arteritis

Ophthalmic Manifestations of Giant Cell Arteritis

“…19,27,50 In one single-center prospective series of patients diagnosed with GCA, new diplopia was reported to occur in 27% at the time of diagnosis. 50 Diplopia in the context of GCA can be temporary or permanent and can occur in the absence of systemic symptoms. 51 In a large multicenter study including 27 patients who presented with diplopia from GCA, the majority (58%) described other accompanying visual symptoms, 26% had simultaneous vision loss due to ocular ischemic lesions at presentation, and nearly all had significantly elevated serum erythrocyte sedimentation rate and C-reactive protein compared with age-matched controls with diplopia from other etiologies.…”

“…52 In another study, ocular ischemia was seen in 44% of patients presenting with diplopia due to GCA. 50 Third, fourth, and sixth cranial nerve palsies have each been rarely described as presenting clinical manifestations of GCA, and ocular dysmotility can improve or resolve after treatment with steroid and/or immunosuppressive therapy. [51][52][53][54][55][56][57] Multiple simultaneous ocular motor cranial neuropathies at presentation have also been reported in histologically confirmed GCA.…”

Diagnostik und Therapie der Riesenzellarteriitis

“…Etabliert haben sich neben der First-line-Diagnostik mittels der FKDS zusätzlich fakultativ noch die hochauflösende Magnetresonanztomographie (MRT), die Computertomographie (CT) bzw. CT-Angiographie (CTA) sowie die 18…”

“…60 % der Patienten innerhalb weniger Tage auch das andere Auge betroffen [ 1 ]. Eine Ischämie der extraokulären Augenmuskeln kann zu Doppelbildern führen, die im Gegensatz zur eingetretenen Erblindung unter Therapie in der Regel reversibel sind [ 18 ].…”

Retinal Vessel Oxygen Saturation in Giant Cell Arteritis Patients without Ocular Symptoms

“…A review of published reports reveals that ocular symptoms, such as amaurosis fugax, diplopia, eye pain, and visual loss, may be the first manifestation of GCA. According to the study design, ophthalmic involvement is reported with an incidence between 26 and 70 % [5][6][7][8][9]. Early diagnosis and timely aggressive corticosteroid treatment are of paramount importance to prevent visual loss and blindness in GCA [3,10,11].…”