Incidence and prevalence of ulcerative colitis in the Songpa-Kangdong district, Seoul, Korea, 1986–1997

Yang, Suk-Kyun; Hong, Weon‐Seon; Min, Young Il; Kim, Hak Yang; Rhee, Poong–Lyul; Chang, Dong Kyung; Song, In Sung; Jung, Sung Ae; Park, Eung-Bum; Yoo, Hyo Min; Lee, Jaewoong; Kim, Young Kyun

doi:10.1016/s0016-5085(00)81382-7

Cited by 61 publications

(104 citation statements)

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“…The combined prevalence of the two diseases in the West and in Asia has been increasing significantly over the last decade; the prevalence rate of UC and of CD in the Japanese population was estimated to be 6.31 and 0.88 per 100,000 in 1985, but the rate increased to 18.12 and 5.85 per 100,000 in 2006 (Hilmi et al 2006). A similar increasing trend in the annual incidence was observed in Korea, Singapore and China (Law et al 1998;Yang et al 2000;Leong et al 2004). Although these values in Asian countries were still relatively low when compared to Western countries (Loftus 2004), IBDs are now thought to be common diseases in Asia.…”

Section: Introductionmentioning

confidence: 79%

Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn’s disease in Japanese patients

et al. 2007

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Inflammatory bowel diseases, Crohn's disease (CD) and ulcerative colitis are characterised by chronic transmural, segmental and typically granulomatous inflammation of the gut. Each has a peak age of onset in the second to fourth decades of life and prevalence has been increasing significantly in both Western countries and Japan over the last decade, while their pathogenesis remains largely unknown. Recently, positive association of CD with the variants in interleukin 23 receptor (IL23R), autophagyrelated 16-like 1 (ATG16L1) genes and chromosome 5p13.1 locus was reported through genome-wide association studies which are now recognised as a robust tool for the identification of susceptibility genes for complex diseases. To examine an association of reported susceptible variants in the three loci with Japanese CD patients, a total of 484 CD patients and 439 controls were genotyped. No evidence of positive association for any of these loci with CD was found in the Japanese population, even after clinically stratified subgroups of CD were used. Our result revealed a distinct ethnic difference of genetic background of CD that we reported previously in other genes between Japanese and Caucasian populations. Further genetic studies are required to confirm our findings with ethnically divergent populations.

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Section: Introductionmentioning

confidence: 79%

Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn’s disease in Japanese patients

et al. 2007

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“…It is noted that the incidence of IBD is increasing in the Asian population [22,23] . They are among the group of chronic disorders associated with periods of remission and unpredictable relapses.…”

Section: Discussionmentioning

confidence: 99%

Faecal incontinence and health related quality of life in inflammatory bowel disease patients: Findings from a tertiary care center in South Asia

Subasinghe

Navarathna

Samarasekera

2016

WJGPT

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AIM:To analyze the frequency and severity of faecal incontinence (FI) and its effect on the quality of life (QOL) in inflammatory bowel disease (IBD) patients. METHODS:All patients who attended surgical and medical gastroenterology outpatient clinics in a tertiary care center with an established diagnosis of either ulcerative colitis (UC) or Crohn's disease (CD) over a period of 10 mo were included in this study. Before enrollment into the study, the patients were explained about the study and informed consent was obtained. The patients with unidentified colitis were excluded. The data on demographics, disease characteristics, FI (Vaizey score), and quality of life (IBD-Q) were collected. Data were analyzed using SPSS version 21. RESULTS:There were 184 patients (women = 101, 54.9%; UC = 153, 83.2%) with a female preponderance for UC (male/female ratio = 1:1.5) and a male preponderance for CD (male/female = 2:1). Forty-eight (26%) patients reported symptoms of FI. Among the patients with FI, 70.8% were women (n = 34) and 29.2% were men (n = 14) with an average age of 52.7 years (range, 20-78 years). Average age of onset of FI was 48.6 (range, 22-74) years. Ten percent (n = 5) reported regular FI. Faecal incontinence and health related quality of life in inflammatory bowel disease patients: Findings from a tertiary care center in South AsiaDuminda Subasinghe, Navarathna Mudiyanselage Meththananda Navarathna, Dharmabandhu Nandadeva Samarasekera Duminda Subasinghe, Navarathna Mudiyanselage Meththananda Navarathna, Dharmabandhu Nandadeva Samarasekera, Department of Surgery, Faculty of Medicine, University Surgical Unit, the National Hospital of Sri Lanka, Colombo 08, Sri LankaAuthor contributions: Subasinghe D, Navarathna NMM and Samarasekera DN were involved in study planning, data collection and analysis, and writing of the manuscript; all authors read and approved the final manuscript.Institutional review board statement: This study was approved by the ethics review committee of the National Hospital of Sri Lanka.Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment. Conflict-of-interest statement:The authors of this manuscript having no conflicts of Interest to disclose. Data sharing statement:There is no additional data available.Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/ licenses/by-nc/4.0/ Prospective StudyIncontinence to flatus was seen in 33.3% (n = 16), to liquid faeces in 56.2% (n = 27), to solid faeces in 6.2% (n = 3) and to all three in 4.1% (n = 2). Twenty-one ...

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“…In addition, though figures are still low, Leong et al [20] reported a three-fold increase in the incidence of CD in the Chinese population of Hong Kong, from 0. [21] . Recent reviews from Japan also report an increase in the incidence and prevalence of IBD.…”

Section: Incidence Of Ibd In Other Parts Of the World: East Europe Amentioning

confidence: 99%

“…Hospital-based investigations reported that the incidence of UC was 1.95/10 5 , and the prevalence was 18.12/10 5 in 1991 [21] . In a retrospective study from Seoul, South Korea, the www.wjgnet.com prevalence of UC was 7.57/10 5 , with a significant increase in incidence rates from 0.20/10 5 in 1986-1988 to 1.23/10 5 in 1995-1997 [21] . In Thailand, UC is still uncommon, with only 40 cases reported between 1988 and 2000 [22] .…”

Section: Incidence Of Ibd In Other Parts Of the World: East Europe Amentioning

confidence: 99%

Recent trends in the epidemiology of inflammatory bowel diseases: Up or down

Lakatos¹

2006

WJG

382

231

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Inflammatory bowel disease (IBD) is traditionally considered to be common in the Western world, and its incidence has sharply increased since the early 1950s. In contrast, until the last decade, low prevalence and incidence rates have been reported from other parts of the world including Eastern Europe, South America, Asia and the Pacific region. Recent trends indicate a change in the epidemiology of IBD with previously low incidence areas now reporting a progressive rise in the incidence, while in West European and North American countries the figures have stabilized or slightly increased, with decreasing incidence rates for ulcerative colitis. Some of these changes may represent differences in diagnostic practices and increasing awareness of the disease. The quality of studies is also variable. Additional epidemiologic studies are needed to better define the burden of illness, explore the mechanism of association with environmental factors, and identify new risk factors.

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Incidence and prevalence of ulcerative colitis in the Songpa-Kangdong district, Seoul, Korea, 1986–1997

Cited by 61 publications

References 0 publications

Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn’s disease in Japanese patients

Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn’s disease in Japanese patients

Faecal incontinence and health related quality of life in inflammatory bowel disease patients: Findings from a tertiary care center in South Asia

Recent trends in the epidemiology of inflammatory bowel diseases: Up or down

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