Incidence and Prevalence of Primary Hyperparathyroidism in a Racially Mixed Population

Yeh, Michael W.; Ituarte, Philip H.G.; Zhou, Hui; Nishimoto, Stacie; Liu, In‐Lu Amy; Harari, Avital; Haigh, Philip I.; Adams, Annette L.

doi:10.1210/jc.2012-4022

Cited by 561 publications

(415 citation statements)

References 23 publications

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“…PHPT, together with hypercalcaemia of malignancy, accounts for 90% of all hypercalcaemic states. PHPT is a very common endocrine disease, with an incidence of approximately 25/100,000 persons-year in the male US population and 65/100,000 persons-year in the female US population; age-corrected prevalence is 85/100,000 in men and 233/100,000 in women (16). PHPT is more common in women (the female/male ratio is approximately 2:1, and increases up to 5:1 after the age of 75 years) (17).…”

Section: Definition Epidemiologymentioning

confidence: 99%

Guidelines for the diagnosis, prevention and management of osteoporosis

et al. 2016

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Osteoporosis poses a significant public health issue. National Societies have developed Guidelines for the diagnosis and treatment of this disorder with an effort of adapting specific tools for risk assessment on the peculiar characteristics of a given population. The Italian Society for Osteoporosis, Mineral Metabolism and Bone Diseases (SIOMMMS) has recently revised the previously published Guidelines on the diagnosis, riskassessment, prevention and management of primary and secondary osteoporosis. The guidelines were first drafted by a working group and then approved by the board of SIOMMMS. Subsequently they received also the endorsement of other major Scientific Societies that deal with bone metabolic disease. These recommendations are based on systematic reviews of the best available evidence and explicit consideration of cost effectiveness. When minimal evidence is available, recommendations are based on leading experts' experience and opinion, and on good clinical practice. The osteoporosis prevention should be based on the elimination of specific risk factors. The use of drugs registered for the treatment of osteoporosis are recommended when the benefits overcome the risk, and this is the case only when the risk of fracture is rather high as measured with variables susceptible to pharmacological effect. DeFRA (FRAX® derived fracture risk assessment) is recognized as a useful tool for easily estimate the long-term fracture risk. Several secondary forms of osteoporosis require a specific diagnostic and therapeutic management

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Section: Definition Epidemiologymentioning

confidence: 99%

Guidelines for the diagnosis, prevention and management of osteoporosis

et al. 2016

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“…The incidence of primary hyperparathyroidism ranges from 34 to 120 per 100,000 in women and 13 to 36 per 100,000 in men [1] and may be caused by parathyroid adenoma, hyperplasia, or rarely, parathyroid carcinoma [2]. Secondary and tertiary hyperparathyroidism are mostly found in patients with chronic kidney disease with prevalence inversely proportional to renal function [3].…”

Section: Introductionmentioning

confidence: 99%

Diagnostic accuracy of planar, SPECT, and SPECT/CT parathyroid scintigraphy protocols in patients with hyperparathyroidism

et al. 2018

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“…Primary hyperparathyroidism is a relatively common disease with a prevalence rate of 1-7 per 1,000 adults (1). The most common cause of primary hyperparathyroidism is parathyroid adenoma (2).…”

Section: Introductionmentioning

confidence: 99%

Management of a Parathyroid Adenoma With Radiofrequency Ablation: A Case Report

Sattarinezhad

Rasekhi

Soveid

2016

Iran Red Crescent Med J

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Introduction: The standard treatment for symptomatic primary hyperparathyroidism due to parathyroid adenoma is surgery, but in patients who are not good candidates for surgery, other treatment modalities including ethanol ablation, laser ablation, ultrasound wave ablation, and radiofrequency ablation are used. We describe a patient with multiple medical problems and a parathyroid adenoma who was treated with radiofrequency ablation. Case Presentation: A 47-year-old patient was referred to our hospital (Namazi hospital, Shiraz, Iran) in April, 2015 with intracranial hemorrhage, as well as high serum calcium and PTH (parathyroid hormone) levels (12.1 mg/dL and 1062 pg/mL, respectively), who had a parathyroid adenoma. Radiofrequency ablation was performed for the patient after he was stabilized, and three days later, his serum calcium and PTH levels decreased to 8.9 mg/dL and 38 pg/mL, respectively, and there was abnormal uptake according to the post-ablation parathyroid scan. The patient was followed for 12 months in our endocrine clinic, during which time he was in good general condition, with normal serum calcium, phosphate, and parathyroid hormone levels. Conclusions: Radiofrequency ablation may be used successfully in the treatment of parathyroid adenoma when a patient cannot tolerate surgery.

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Incidence and Prevalence of Primary Hyperparathyroidism in a Racially Mixed Population

Abstract: PHPT is the predominant cause of hypercalcemia and is increasingly prevalent. Substantial differences are found in the incidence and prevalence of PHPT between races.

Cited by 561 publications

References 23 publications

Guidelines for the diagnosis, prevention and management of osteoporosis

Guidelines for the diagnosis, prevention and management of osteoporosis

Diagnostic accuracy of planar, SPECT, and SPECT/CT parathyroid scintigraphy protocols in patients with hyperparathyroidism

Management of a Parathyroid Adenoma With Radiofrequency Ablation: A Case Report

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