Incidence and prevalence of eosinophilic oesophagitis: Are we reaching a plateau?

Masclee, Gwen; Bredenoord, Albert J.

doi:10.1002/ueg2.12282

Cited by 2 publications

(1 citation statement)

References 7 publications

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“…In a Danish study, the incidence rate of EoE increased from 3.9 per 100,000 person-years in 2011 to 11.7 per 100,000 person-years in 2018 (70). The question was raised if a plateau was reached (71). Across a number of studies, especially in children, culprit foods are identified by assessing the impact of elimination diets and individual reintroduction.…”

Section: Eosinophilic Oesophagitismentioning

confidence: 99%

An ESPGHAN Position Paper on the Diagnosis, Management, and Prevention of Cow's Milk Allergy

Vandenplas

Broekaert

Domellöf

et al. 2024

J. pediatr. gastroenterol. nutr.

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A previous guideline on cow's milk allergy (CMA) developed by the European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) was published in 2012. This position paper provides an update on the diagnosis, treatment, and prevention of CMA with focus on gastrointestinal manifestations. All systematic reviews and meta-analyses regarding prevalence, pathophysiology, symptoms, and diagnosis of CMA published after the previous ESPGHAN document were considered. Medline was searched from inception until May 2022 for topics that were not covered in the previous document. After reaching consensus on the manuscript, statements were formulated and voted on each of them with a score between 1 and 9. A score of ≥6 was arbitrarily considered as agreement. Available evidence on the role of dietary practice in the prevention, diagnosis and management of CMA was updated and recommendations formulated. CMA in exclusively breastfed infants exists, but is uncommon and suffers from over-diagnosis. CMA is also over-diagnosed in formula and mixed fed infants. Changes in stool characteristics, feeding aversion or occasional spots of blood in stool are common and in general should not be considered as diagnostic of CMA, irrespective of preceding consumption of cow's milk. Over-diagnosis of CMA occurs much more frequently than under-diagnosis; both have potentially harmful consequences. Therefore, the necessity of a challenge test after a short diagnostic elimination diet of 2-4 weeks is recommended as the cornerstone of the diagnosis. This position paper contains sections on nutrition, growth, cost and quality of life.

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Section: Eosinophilic Oesophagitismentioning

confidence: 99%

An ESPGHAN Position Paper on the Diagnosis, Management, and Prevention of Cow's Milk Allergy

Vandenplas

Broekaert

Domellöf

et al. 2024

J. pediatr. gastroenterol. nutr.

View full text Add to dashboard Cite

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Endoscopic Diagnosis and Response Evaluation in Patients with Eosinophilic Esophagitis

Sorge

Masclee

Bredenoord

2023

Curr Treat Options Gastro

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Purpose of review The aim of this review is to provide practical guidance for clinicians to support the optimal use of endoscopy in both the diagnosis and the evaluation of treatment response in patients with eosinophilic esophagitis (EoE). Recent findings The systematic and high-quality assessment and grading of EoE endoscopic features improves EoE detection. Fibrotic complications of EoE that negatively impact patients’ symptoms and quality of life can be detected and treated through endoscopy. The correlation between endoscopic features of EoE and histological activity remains challenging. However, assessment of endoscopic activity is fast and reliable in the evaluation of treatment response and, therefore, is supported by current guidelines. New modalities such as FLIP panometry and molecular markers for diagnosis and monitoring of EoE are promising, but whether they may replace endoscopy in guiding treatment of EoE needs to be ascertained. Summary Endoscopy plays a central role in EoE management, both in routine practice and in clinical trials. Endoscopy is pivotal in EoE diagnosis and response evaluation since it allows the direct assessment of endoscopic disease activity and, indirectly, the histological evaluation. Consequently, together with clinical and histological evaluation, endoscopy is rapidly becoming essential in monitoring the effectiveness of therapy in patients with EoE.

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Incidence and prevalence of eosinophilic oesophagitis: Are we reaching a plateau?

Cited by 2 publications

References 7 publications

An ESPGHAN Position Paper on the Diagnosis, Management, and Prevention of Cow's Milk Allergy

An ESPGHAN Position Paper on the Diagnosis, Management, and Prevention of Cow's Milk Allergy

Endoscopic Diagnosis and Response Evaluation in Patients with Eosinophilic Esophagitis

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