Incidence and predictors of short- and long-term complications in pacemaker therapy: The FOLLOWPACE study

Udo, Erik O.; Zuithoff, Nicolaas P.A.; Hemel, Norbert M. van; Cock, Carel C. de; Hendriks, T.; Doevendans, Pieter A.; Moons, Karel G.M.

doi:10.1016/j.hrthm.2011.12.014

Cited by 474 publications

(357 citation statements)

References 31 publications

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“…While such risks are statistically rare, they represent an economic burden to hospitals and the healthcare system because of the large number of pacemaker patients (over 4 million worldwide). In the Follow Pace study, the rate of complications was 5.5% in the 6-year follow up of an unselected population of pacemaker patients [70]. These data are confirmed by the Danish registry that reported a complication rate of 7% in around 6000 patients with a pacemaker [71].…”

Section: The Future Of Electrical Therapies In Laminopathiesmentioning

confidence: 82%

“…These data are confirmed by the Danish registry that reported a complication rate of 7% in around 6000 patients with a pacemaker [71]. The rates of the specific types of device complications are: lead-related in 2–5%, pocket-related in 1–4%, infection-related in 1–2% and pneumothorax in 1–2% [70,71]. The option of leadless pacemakers may minimize the risk of these complications.…”

Section: The Future Of Electrical Therapies In Laminopathiesmentioning

confidence: 85%

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Cardiolaminopathies from bench to bedside: challenges in clinical decision-making with focus on arrhythmia-related outcomes

Boriani

Biagini

Ziacchi

et al. 2018

Nucleus

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Lamin A/C gene mutations can be associated with cardiac diseases, usually referred to as ‘cardiolaminopathies’ characterized by arrhythmic disorders and/or left ventricular or biventricular dysfunction up to an overt picture of heart failure. The phenotypic cardiac manifestations of laminopathies are frequently mixed in complex clinical patterns and specifically may include bradyarrhythmias (sinus node disease or atrioventricular blocks), atrial arrhythmias (atrial fibrillation, atrial flutter, atrial standstill), ventricular tachyarrhythmias and heart failure of variable degrees of severity. Family history, physical examination, laboratory findings (specifically serum creatine phosphokinase values) and ECG findings are often important ‘red flags’ in diagnosing a ‘cardiolaminopathy’. Sudden arrhythmic death, thromboembolic events or stroke and severe heart failure requiring heart transplantation are the most dramatic complications of the evolution of cardiolaminopathies and appropriate risk stratification is clinically needed combined with clinical follow-up. Treatment with cardiac electrical implantable devices is indicated in case of bradyarrhythmias (implant of a device with pacemaker functions), risk of life-threatening ventricular tachyarrhythmias (implant of an ICD) or in case of heart failure with wide QRS interval (implant of a device for cardiac resynchronization). New technologies introduced in the last 5 years can help physicians to reduce device-related complications, thanks to the extension of device longevity and availability of leadless pacemakers or defibrillators, to be implanted in appropriately selected patients. An improved knowledge of the complex pathophysiological pathways involved in cardiolaminopathies and in the determinants of their progression to more severe forms will help to improve clinical management and to better target pharmacological and non-pharmacological treatments.

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Section: The Future Of Electrical Therapies In Laminopathiesmentioning

confidence: 82%

Section: The Future Of Electrical Therapies In Laminopathiesmentioning

confidence: 85%

Cardiolaminopathies from bench to bedside: challenges in clinical decision-making with focus on arrhythmia-related outcomes

Boriani

Biagini

Ziacchi

et al. 2018

Nucleus

View full text Add to dashboard Cite

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“…Therefore, in this large Silesian Center Defibrillator registry, we analyzed baseline characteristic of patients included in the registry and the incidence and predictors of early and long-term ICD/CRT-D follow-up complications. We considered complications within first 2 months early ones as this is a generally accepted time period in which complications directly related to an initial surgical procedure as device implantation will have emerged [13]. The frequent practice of publishing only in-hospital complications may significantly underestimate true complication occurrence.…”

Section: Discussionmentioning

confidence: 99%

“…Its occurrence is reported in 2.9-9.5% of cases and it was usually treated conservatively. Evacuation of hematoma is required in 0.3-2% of implantation and related with a 15-fold increase in infection risk [13,14]. Many hematomas can be avoided by substantial preparing the patient before surgery.…”

Section: Discussionmentioning

confidence: 99%

Complications in recipients of cardioverter-defibrillator or cardiac resynchronization therapy: Insights from Silesian Center Defibrillator registry

et al. 2017

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Background: Current real-life information from all-comers registries from middle and east Europe about the incidence and type of complications during long-term follow-up of patients with cardiovertersdefibrillators (ICD) and cardiac resynchronization devices-defibrillators (CRT-D) is still insufficient. The aim of the study was to assess the incidence and determinants of short-and long-term complications related to implantable ICD and CRT-D. Methods: We studied 1,105 recipients hospitalized in our center in 2009-2013, followed for a mean of 2.4 years (total of 2,652 patient-years). The independent association between ICD and CRT-D recipients' and implantation-procedures' characteristics with the incidence of complications was analyzed follow-up. (Cardiol J 2017; 24, 5: 515-522)

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“…Typical pacemaker battery life cycles are in the range of 8-10 years 1 ; however, they strongly depend on the device type and usage. Therefore, many patients are confronted with repeated surgical interventions 2 that increase the risk of complications such as infections or bleedings [3][4][5] and are costly. Furthermore, the battery accounts for a majority of a pacemaker's volume and weight.…”

Section: Introductionmentioning

confidence: 99%

The Swiss approach for a heartbeat-driven lead- and batteryless pacemaker

et al. 2017

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Incidence and predictors of short- and long-term complications in pacemaker therapy: The FOLLOWPACE study

Cited by 474 publications

References 31 publications

Cardiolaminopathies from bench to bedside: challenges in clinical decision-making with focus on arrhythmia-related outcomes

Cardiolaminopathies from bench to bedside: challenges in clinical decision-making with focus on arrhythmia-related outcomes

Complications in recipients of cardioverter-defibrillator or cardiac resynchronization therapy: Insights from Silesian Center Defibrillator registry

The Swiss approach for a heartbeat-driven lead- and batteryless pacemaker

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