Incidence and Outcomes of Severe Anaphylaxis in Paediatric Patients in Atlantic Canada

Krmpotic, Kristina; Weisser, Caroline; O'Hanley, Alexandra; Soder, Christian

doi:10.1055/s-0039-1683869

Cited by 4 publications

(2 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Severe anaphylaxis requiring ICU admission is a rare event and difficult to study since the number of affected patients is usually small [32]. We identified that 10.57% of children with anaphylaxis required admission to the ICU.…”

Section: Discussionmentioning

confidence: 99%

Trends and Hospital Outcomes in HOSPITAL Admissions for Anaphylaxis in Children with and without Asthma in Spain (2016–2021)

De Miguel-Díez,

Lopez-de-Andres,

Caballero-Segura

et al. 2023

JCM

View full text Add to dashboard Cite

(1) Background: To assess and compare the temporal trends in the incidence, characteristics and hospital outcomes among children with and without asthma who were hospitalized with anaphylaxis in Spain from 2016 to 2021, and identify the variables associated with severe anaphylaxis among children with asthma. (2) Methods: An observational, retrospective study was conducted using a population-based database. The study population included pediatric patients with anaphylaxis. This population was stratified based on whether they had asthma. (3) Results: The number of hospital admissions was stable from 2016 to 2019, dropping in 2020 and raising to the highest number in 2021. A total of 60.63% of hospitalizations occurred in boys and the most common anaphylactic reactions were due to food consumption (67.28%), increasing over time. The in-hospital mortality (IHM) remained stable and under 1% in all the years studied. The incidence of anaphylaxis was 2.14 times higher in children with asthma than in those without asthma (IRR 2.14; 95% CI 1.87–2.44). Furthermore, it was 1.79 times higher in boys with asthma than in those without asthma (IRR 1.79; 95% CI 1.06–2.45) and 2.68 times higher in girls with asthma than in those without asthma (IRR 2.68; 95% CI 2.23–3.12). Asthma was not associated with severe anaphylaxis (OR 1.31; 95% CI 0.88–1.96). (4) Conclusions: The number of hospitalizations for anaphylaxis in children remained stable from 2016 to 2019, dropping in 2020 and recovering in 2021. IHM was low and remained stable during the study period. The incidence of hospitalizations for anaphylaxis was higher in asthmatic children than in non-asthmatics, but there were no differences in the occurrence of severe anaphylaxis among them.

show abstract

Section: Discussionmentioning

confidence: 99%

Trends and Hospital Outcomes in HOSPITAL Admissions for Anaphylaxis in Children with and without Asthma in Spain (2016–2021)

De Miguel-Díez,

Lopez-de-Andres,

Caballero-Segura

et al. 2023

JCM

View full text Add to dashboard Cite

show abstract

“…The timely administration of epinephrine is important in pediatric anaphylaxis since it can prevent hospitalization and fatalities [ 12 , 28 ]. However, the lack of a standardized protocol, low awareness of guidelines, and concern about side effects can all cause delays in epinephrine administration [ 19 ].…”

Section: Discussionmentioning

confidence: 99%

The Timely Administration of Epinephrine and Related Factors in Children with Anaphylaxis

Myung-Jin

Lee

Han

et al. 2022

JCM

View full text Add to dashboard Cite

Anaphylaxis is a severe allergic reaction that requires immediate recognition and intervention. This study investigated the factors related to the timely administration of epinephrine in cases of pediatric anaphylaxis. We performed a retrospective chart review of 107 patients who visited a pediatric emergency center with anaphylaxis between 2015 and 2017. In total, 76 patients received epinephrine injections. We analyzed factors including allergy history, anaphylaxis signs and symptoms, allergen sensitization, anaphylaxis triggers, and time of epinephrine injection. Anaphylactic patients who received epinephrine took a median of 50 min to arrive at the hospital, and patients who did not receive epinephrine took a median of 94 min. Epinephrine administration was significantly delayed by more than 60 min from symptom onset in patients <2 years old. Patients presenting with wheezing symptoms or history of bronchial asthma were significantly more likely to receive epinephrine within 60 min of symptoms onset, while patients with food allergen sensitization were significantly more likely to receive epinephrine within 30 min of hospital arrival. Wheezing, history of asthma, age (≥2 years old), food triggers, and food allergen sensitivity were significant factors for the rapid administration of epinephrine. An immediate diagnosis of anaphylaxis and a rapid administration of epinephrine are essential.

show abstract

Lebensrettende Maßnahmen bei Kindern (Paediatric Life Support, PLS)

Voorde

Turner

Djakow

et al. 2021

Notfall Rettungsmed

View full text Add to dashboard Cite

Die Leitlinien des European Resuscitation Council (ERC) zu den lebensrettenden Maßnahmen bei Kindern (Paediatric Life Support, PLS) basieren auf dem 2020 verfassten „International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations“ der ILCOR (International Liaison Committee on Resuscitation). Dieses Kapitel beinhaltet Leitlinien zur Behandlung kritisch kranker oder verletzter Säuglinge, von Kindern und Jugendlichen vor, während und nach einem Atem-Kreislauf-Stillstand.

show abstract

Incidence and Outcomes of Severe Anaphylaxis in Paediatric Patients in Atlantic Canada

Cited by 4 publications

References 6 publications

Trends and Hospital Outcomes in HOSPITAL Admissions for Anaphylaxis in Children with and without Asthma in Spain (2016–2021)

Trends and Hospital Outcomes in HOSPITAL Admissions for Anaphylaxis in Children with and without Asthma in Spain (2016–2021)

The Timely Administration of Epinephrine and Related Factors in Children with Anaphylaxis

Lebensrettende Maßnahmen bei Kindern (Paediatric Life Support, PLS)

Contact Info

Product

Resources

About