Incidence and medical complications of COVID-19 in the total laryngectomy population: A population-based study

Patel, Nilam D.; Cabrera, Claudia I.; Fowler, Nicole; Li, Shawn; Thuener, Jason; Teknos, Theodoros N.; Rezaee, Rod; Tamaki, Akina

doi:10.1016/j.oraloncology.2023.106353

Cited by 3 publications

(1 citation statement)

References 14 publications

(15 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For example, individuals with early forms of cancer may have developed a weaker immune response against the malignancy due to the direct effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the immune system [6]. Additional factors include the global disruptions in cancer screening, diagnosis and treatment that may have been associated with significant delay in diagnosis and treatment [7], but also the increased risk of respiratory complications since laryngeal cancers impair breathing and respiratory function, conditions that could be aggravated by SARS-CoV-2 infection [8]. Therefore, to garner information on recent mortality for laryngeal cancer, especially during the last years (some of which dominated by the COVID-19 pandemic), we perform an analysis of real-world data made available by the US Centers for Disease Control and Prevention (CDC).…”

Section: Introductionmentioning

confidence: 99%

Mortality for Laryngeal Cancer before and during the COVID-19 Pandemic

Nocini,

Lippi,

Mattiuzzi

2024

Preprint

View full text Add to dashboard Cite

(1) Background: The interplay between coronavirus disease 2019 (COVID-19) and laryngeal cancer represents a substantial challenge for both patients and healthcare. To garner information on recent mortality data for laryngeal cancer, including during the COVID-19 pandemic, we analyzed real-world data from the US Centers for Disease Control and Prevention (CDC). (2) Methods: We searched the CDC WONDER on-line database 2018-2022 using with the ICD-10 code for laryngeal cancer (C32; malignant neoplasm of larynx). We also performed a sub-analysis between genders, and across ten-year age groups. Data were analyzed with one-way analysis of variance (ANOVA) and Tukey post-hoc test. (3) Results: The trend of age-adjusted mortality ×100,000 did not change significantly between 2018-2022 (p=0.553). Males had higher age-adjusted mortality rates (M/F ratios between 4.6 and 5.0), but no significant variation was found in both genders (males: p=0.676; females: p=0.596). Although the mortality rate remained unchanged in people aged 35-84 years, the variation reached statistical significance in those aged 85 or older (p=0.004), displaying significant increase in 2021 compared to 2018 (p=0.006) and 2019 (p=0.039). (4) Conclusions: The impact of the COVID-19 pandemic on mortality for laryngeal cancer seemed to be relatively modest in the general US population. Nevertheless, closer attention must be paid to older people, in whom the unfavorable consequences of misdiagnosis or mistreating can be exacerbated.

show abstract

Section: Introductionmentioning

confidence: 99%

Mortality for Laryngeal Cancer before and during the COVID-19 Pandemic

Nocini,

Lippi,

Mattiuzzi

2024

Preprint

View full text Add to dashboard Cite

show abstract

Perceptions and practices of people with a total laryngectomy during COVID-19 pandemic: A mixed methods analysis

Searl,

Genoa,

Fritz

et al. 2024

American Journal of Otolaryngology

View full text Add to dashboard Cite

Mortality of Laryngeal Cancer before and during the COVID-19 Pandemic

Nocini,

Lippi,

Mattiuzzi

2024

COVID

View full text Add to dashboard Cite

(1) Background: The interplay between coronavirus disease 2019 (COVID-19) and laryngeal cancer represents a substantial challenge for both patients and healthcare. To garner information on recent mortality data for laryngeal cancer, including during the COVID-19 pandemic, we analyzed real-world data from the US Centers for Disease Control and Prevention (CDC). (2) Methods: We searched the CDC WONDER online database 2018–2022 using the ICD-10 code for laryngeal cancer (C32; malignant neoplasm of the larynx). We also performed a sub-analysis between genders and across ten-year age groups. The data were analyzed with one-way analysis of variance (ANOVA) and Tukey’s post hoc test. (3) Results: The trend of age-adjusted mortality ×100,000 did not change significantly between the years 2018 and 2022 (p = 0.553). Males had higher age-adjusted mortality rates (M/F ratios between 4.6 and 5.0), but no significant variation was found in both genders (males: p = 0.676; females: p = 0.596). Although the mortality rate remained unchanged in people aged 35–84 years, the variation reached statistical significance in those aged 85 or older (p = 0.004), displaying a significant increase in 2021 compared to 2018 (p = 0.006) and 2019 (p = 0.039). (4) Conclusions: The impact of the COVID-19 pandemic on mortality for laryngeal cancer seems to be relatively modest in the general US population. Nevertheless, closer attention must be paid to older people, for whom the unfavorable consequences of misdiagnosis or mistreatment of this and other types of cancers can be exacerbated.

show abstract

Incidence and medical complications of COVID-19 in the total laryngectomy population: A population-based study

Cited by 3 publications

References 14 publications

Mortality for Laryngeal Cancer before and during the COVID-19 Pandemic

Mortality for Laryngeal Cancer before and during the COVID-19 Pandemic

Perceptions and practices of people with a total laryngectomy during COVID-19 pandemic: A mixed methods analysis

Mortality of Laryngeal Cancer before and during the COVID-19 Pandemic

Contact Info

Product

Resources

About