Incidence and Management of Complex Fibroadenomas

Sklair‐Levy, Miri; Sella, Tamar; Alweiss, Tanir; Craciun, I; Libson, Eugene; Mally, Bella

doi:10.2214/ajr.07.2330

Cited by 115 publications

(114 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Juvenile fibroadenomas were the second most common histology seen in our cohort (5.9%), historically constituting 7% to 8% of all fibroadenoma subtypes [8,28,29]. Up to 10% to 25% of juvenile fibroadenomas can be multiple or bilateral, and most occur in adolescent African American adolescent girls [1,30].…”

Section: Discussionmentioning

confidence: 99%

Breast Imaging-Reporting and Data System (BI-RADS) classification in 51 excised palpable pediatric breast masses

Koning

Davenport

Poole³

et al. 2015

Journal of Pediatric Surgery

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Breast Imaging-Reporting and Data System (BI-RADS) classification in 51 excised palpable pediatric breast masses

Koning

Davenport

Poole³

et al. 2015

Journal of Pediatric Surgery

View full text Add to dashboard Cite

“…Therefore, histological diagnosis is typically unexpected (1,8,9,13,14). The mean age of patients with carcinoma in FA has been reported as 42-44 years, ~20 years subsequent to the peak age of occurrence of FA (15,16).…”

Section: Discussionmentioning

confidence: 99%

Fibroadenoma with an unexpected lobular carcinoma in situ: A case report and review of the literature

Bai

Jiang

et al. 2015

Oncology Letters

View full text Add to dashboard Cite

Abstract. Fibroadenoma (FA) is the most common type of breast lesion in young female individuals. Although malignant transformation in FA is rare, there is evidence of an association with breast carcinoma, particularly in middle-aged females with associated risk factors, such as a strong family history and/or BRCA-1/2 mutations. The current study presents the case of a 44-year-old female exhibiting lobular carcinoma in situ (LCIS) arising within an FA. Over the previous 20 years, numerous lumps were detected in the patient's breasts, all of which were clinically diagnosed as FA and expectantly managed. One year prior to presentation, the patient's father was diagnosed with esophageal cancer, older sister with kidney cancer and the patient herself with a benign ovarian teratoma. The patient presented with one lump in each breast and monitoring was performed using ultrasonography (US). US detected an increase in the size of the two lumps and analysis of the images was used to propose a diagnosis of FA. Therefore, a lumpectomy was performed. Analysis of the frozen section indicated a diagnosis of FA in the right breast, however, a 5-mm LCIS was identified within the FA of the left breast. Subsequent to the identification of three additional lumps in the left breast, a left mastectomy was performed. During a five-year follow-up period, no local recurrence or contralateral breast carcinoma occurred. The present study showed that FAs containing foci of carcinoma in situ can be indistinguishable from benign lesions following imaging, therefore, despite the incidence of carcinoma within FA is estimated at 0.1-0.3%, it should be considered a long-term risk factor for invasive breast cancer. The present describes a case of LCIS arising within an FA and conducts a review of the relevant literature.

show abstract

“…We also observed that complex fibroadenoma made up 0.6% (3) of cases and occurred in patients with average age of 24 years. In Israel, Sklair-Levy et al [19] reported that 15.7% of fibroadenoma were of the complex type.…”

Section: Characteristics Of Fibroadenoma In Nigerian Igbo Femalesmentioning

confidence: 99%

Fibroadenoma in Blacks

Egejuru¹,

Nnadi²,

Duru³

2017

Health

View full text Add to dashboard Cite

Background: Fibroadenoma is the commonest benign tumour of the breast affecting the majority of young females below the age of thirty in our environment. It is a source of concern and psychological problems in females requiring medical attention in our hospitals. Aim: This study describes the clinicopathologic characteristics of fibroadenoma in Eastern Nigerian Igbo females. Methodology: The archives of the Department of Pathology Federal Medical Centre, Owerri was used for the data collection and analyzed using simple statistics. Results: 504 fibroadenomas were analyzed. The average size was 1.99 cm with a range of 0.5 cm to 18 cm. The average age of the patients was 22.6 ± 6.7 years with a range of 9 to 60 years. The peak age of incidence was in the 11 -20 (44.64%) age group followed closely by the 21 -30 (43.45%) age group. The ratio of involvement of the left to the right breast was 1:1.2. Fibroadenoma was 18% multiple and 10.7% bilateral. 5.3% (27), 0.6% (3), and 0.2% (1) of the cases were giant, complex fibroadenoma and malignant breast disease in fibroadenoma respectively. Conclusion: This study has provided insights into the clinicopathologic characteristics of fibroadenoma among Nigerian Igbos and calls for more research in this area in other parts Nigeria and elsewhere.

show abstract

Incidence and Management of Complex Fibroadenomas

Cited by 115 publications

References 19 publications

Breast Imaging-Reporting and Data System (BI-RADS) classification in 51 excised palpable pediatric breast masses

Breast Imaging-Reporting and Data System (BI-RADS) classification in 51 excised palpable pediatric breast masses

Fibroadenoma with an unexpected lobular carcinoma in situ: A case report and review of the literature

Fibroadenoma in Blacks

Contact Info

Product

Resources

About