Incidence and factors associated with portal vein thrombosis in patients with acute pancreatitis: A United States national retrospective study

Chaudhry, Hunza; Sohal, Aalam; Bains, Kanwal; Dhaliwal, Armaan; Dukovic, Dino; Singla, Piyush; Sharma, Raghav; Kohli, Isha; Chintanaboina, Jayakrishna

doi:10.1016/j.pan.2023.03.008

Cited by 5 publications

(3 citation statements)

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“…In a study by Chaudhry et al, PVT was diagnosed in 0.8% of cases admitted with acute pancreatitis. [ 70 ]. Women displayed a 15% lower risk of PVT development (OR −0.85, p < 0.001) [ 70 ].…”

Section: Risk Factors For Portal Vein Thrombosismentioning

confidence: 99%

“…[ 70 ]. Women displayed a 15% lower risk of PVT development (OR −0.85, p < 0.001) [ 70 ]. PVT was related to pancreatic pseudocyst (OR −4.15, p < 0.001), bacteremia (OR −2.66, p < 0.001), sepsis (OR −1.55, p < 0.001), shock (OR −1.68, p < 0.001), and ileus (OR −1.38, p < 0.001).…”

Section: Risk Factors For Portal Vein Thrombosismentioning

confidence: 99%

“…PVT was related to pancreatic pseudocyst (OR −4.15, p < 0.001), bacteremia (OR −2.66, p < 0.001), sepsis (OR −1.55, p < 0.001), shock (OR −1.68, p < 0.001), and ileus (OR −1.38, p < 0.001). The development of PVT in subjects with acute pancreatitis was associated with a higher incidence of in-hospital mortality and intensive care unit (ICU) admissions [ 70 ].…”

Section: Risk Factors For Portal Vein Thrombosismentioning

confidence: 99%

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Portal Vein Thrombosis: State-of-the-Art Review

Boccatonda,

Gentilini,

Zanata

et al. 2024

JCM

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Background: Portal vein thrombosis (PVT) is a rare disease with an estimated incidence of 2 to 4 cases per 100,000 inhabitants. The most common predisposing conditions for PVT are chronic liver diseases (cirrhosis), primary or secondary hepatobiliary malignancy, major infectious or inflammatory abdominal disease, or myeloproliferative disorders. Methods: PVT can be classified on the basis of the anatomical site, the degree of venous occlusion, and the timing and type of presentation. The main differential diagnosis of PVT, both acute and chronic, is malignant portal vein invasion, most frequently by hepatocarcinoma, or constriction (typically by pancreatic cancer or cholangiocarcinoma). Results: The management of PVT is based on anticoagulation and the treatment of predisposing conditions. The aim of anticoagulation in acute thrombosis is to prevent the extension of the clot and enable the recanalization of the vein to avoid the development of complications, such as intestinal infarction and portal hypertension. Conclusions: The treatment with anticoagulant therapy favors the reduction of portal hypertension, and this allows for a decrease in the risk of bleeding, especially in patients with esophageal varices. The anticoagulant treatment is generally recommended for at least three to six months. Prosecution of anticoagulation is advised until recanalization or lifelong if the patient has an underlying permanent pro-coagulant condition that cannot be corrected or if there is thrombosis extending to the mesenteric veins.

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Section: Risk Factors For Portal Vein Thrombosismentioning

confidence: 99%

Section: Risk Factors For Portal Vein Thrombosismentioning

confidence: 99%

Section: Risk Factors For Portal Vein Thrombosismentioning

confidence: 99%

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