Incidence and distribution of herpes simplex virus types 1 and 2 from genital lesions in college women

Abstract

During a 9-month period, 9,772 women were treated at the student health center's gynecology clinic. Herpes simplex virus was isolated from 30 of 57 patients clinically diagnosed as suffering from a herpetic or herpetic-like genial infection for a virological incidence rate of 0.31%. Using virus plaque diameter in chick embryo cells and heat stability of viral thymidine kinase, 37% of the isolates were classified as herpes simplex virus type 1 and 63% were classified as herpes simplex virus type 2.

Antiviral property and mode of action of a sulphated polysaccharide from Sargassum patens against herpes simplex virus type 2

“…It is estimated that several hundred million individuals are infected with one or more STDs [2]. The STD genital herpes is caused mostly by herpes simplex virus type 2 (HSV-2), although a proportion of cases are attributable to HSV-1 [3]. At least 20% of people in the United States have been infected with HSV-2, which is usually transmitted sexually and can cause recurrent genital ulcers [4,5].…”

Review: Identifying potential pitfalls in conventional herpes simplex virus management

“…39 One year later in 1977, Kalinyak et al corroborated these findings, identifying HSV-1 as the causative agent in 37% of genital herpes infections. 40 Despite the pre-ponderance of evidence to the contrary, the popular tenet that HSV-2 causes the large majority of genital herpes infections remains. The clinical ramifications of this fallacy are undeniable.…”

Incidence of herpes simplex virus types 1 and 2 in penile lesions of college men

“…In two previous reports we examined the HSV type distribution in a group of college females and found HSV-I rates of 33% and 40%, respectively [Kalinyak et al, 1977;McCaughtry et al, 19821. However, the HSV-I and HSV-2 distribution in penile lesions in college males from this population has not been reported.…”

“…Recent studies have indicated that HSV-1 is being detected with increasing frequency in female genitalia [Kalinyak et al, 1977;McCaughtry et al, 1982;Balachandran et al, 19821. In two previous reports we examined the HSV type distribution in a group of college females and found HSV-I rates of 33% and 40%, respectively [Kalinyak et al, 1977;McCaughtry et al, 19821.…”

“…A limited number of studies have been done on penile herpes simplex virus (HSV) infections. This is probably because interest has been directed toward the more serious consequences of the disease in the female, including the risk of neonatal infection in the birth canal at delivery [Naib et al, 1970;Nahmias et al, 1971;Harger et al, 19831 and the potential association of this virus with vulvar and cervical cancer [Rawls et al, 1973;Kaufman et al, 1981;Cabral et al, 19821. In those studies of genital HSV in males that have been done, it has been reported that the virus was isolated from various urogenital tissue [Centifanto et al, 19723 and from the urethra of asymptomatic males [Nahmias et al, 19761. In two studies in which the virus was typed, all samples were found to be HSV-2 [Centifanto et al, 1972;Adams et al, 19761, while in a third study 3% of the isolates were HSV-1 [Nahmias et al, 19761. In studies on single cases, the penile specimen in one instance was fou?d to contain both HSV-I and HSV-2 [Fife et al, 19831, while in another instance HSV-1 was responsible for severe balanitis [Powers et al, 19821. Recent studies have indicated that HSV-1 is being detected with increasing frequency in female genitalia [Kalinyak et al, 1977;McCaughtry et al, 1982;Balachandran et al, 19821. In two previous reports we examined the HSV type distribution in a group of college females and found HSV-I rates of 33% and 40%, respectively [Kalinyak et al, 1977;McCaughtry et al, 19821. However, the HSV-I and HSV-2 distribution in penile lesions in college males from this population has not been reported.…”