Incidence and clinical predictors of primary opportunistic deep cutaneous mycoses in solid organ transplant recipients: a multicenter cohort study

Tessari, Gianpaolo; Naldi, Luigi; Piaserico, Stefano; Boschiero, Luigino; Nacchia, Francesco; Forni, Alberto; Rugiu, Carlo; Faggian, Giuseppe; Dall'Olio, Elena; Fortina, Anna Belloni; Alaibac, Mauro; Sassi, Fabrizia; Gotti, Eliana; Fiocchi, R; Fagioli, Stefano; Girolomoni, Giampiero

doi:10.1111/j.1399-0012.2009.01071.x

Cited by 29 publications

(47 citation statements)

References 28 publications

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“…In the available literature, similarly to our study, KS is more likely to develop in males [12]. Lesions were observed 2 and 9 months post-transplantation, consistently with previous observations which showed that most of the changes appear within 2 years after transplantation [30, 32]. …”

Section: Discussionsupporting

confidence: 91%

Comparison of the incidence of skin cancers in patients on dialysis and after kidney transplantation

Sułowicz¹,

Wojas‐Pelc²,

Ignacak³

et al. 2017

pdia

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IntroductionKidney transplant (KTx) patients on immunosuppressive therapy are predisposed to the development of infections and cancers.AimTo compare the incidence and type of malignant skin lesions in kidney transplant patients and the dialyzed population based on the initiated dermatologic screening.Material and methodsThe study included 598 patients: 486 kidney transplant recipients and 112 patients on maintenance dialysis. All the patients underwent dermatological examination. Only histologically confirmed cancers were included in this study. Age, gender and immunosuppressive therapy administration were also considered. Patients were followed up by a dermatologist for a period of 5 years.ResultsFifty-eight skin cancers; 39 basal cell carcinomas (BCC), 13 squamous cell carcinomas (SCC), 1 Bowen disease, 2 Kaposi sarcoma, 1 malignant melanoma, 1 Merkel cell carcinoma, and 1 fibrosarcoma protuberans were diagnosed in 30 (6.2%) kidney transplant patients, and 8 lesions (7 BCC and 1 SCC) were found in 4 (3.6%) patients on dialysis.ConclusionsThe initiated dermatologic screening program indicates that the risk of skin cancer incidence in post kidney transplant patients receiving immunosuppressive therapy was significantly higher than in patients on dialysis.

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Section: Discussionsupporting

confidence: 91%

Comparison of the incidence of skin cancers in patients on dialysis and after kidney transplantation

Sułowicz¹,

Wojas‐Pelc²,

Ignacak³

et al. 2017

pdia

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show abstract

“…138 In a Sardinian study, 23% of patients who were HHV-8 positive before transplantation developed KS. 139 The incidence of KS among renal transplant recipients may be 3.6% or higher in regions endemic for KS, as compared to the 0.4% incidence in renal transplant recipients in the United States and western Europe.…”

Section: Iatrogenic Ksmentioning

confidence: 99%

Kaposi sarcoma: A continuing conundrum

Schwartz

Micali

Nasca

et al. 2008

Journal of the American Academy of Dermatology

201

212

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“…The median number of treated lesions per patient was 5 (range Q1-Q3: 3-6). Before treatment, the median tumor area per patient was 1658 mm 2 (range Q1-Q3: 399-2365) and median sum of the infiltration score per patient was 5 (range Q1-Q3: [3][4][5][6][7][8].…”

Section: Study Patientsmentioning

confidence: 99%

Imiquimod 5% cream for treatment of HIV-negative Kaposi's sarcoma skin lesions: A phase I to II, open-label trial in 17 patients

Schartz

Chevret

Paz

et al. 2008

Journal of the American Academy of Dermatology

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Incidence and clinical predictors of primary opportunistic deep cutaneous mycoses in solid organ transplant recipients: a multicenter cohort study

Abstract: Primary deep cutaneous opportunistic mycoses in OTR occur mainly in the first two yr after transplantation, in renal transplant recipients, and in older patients.

Cited by 29 publications

References 28 publications

Comparison of the incidence of skin cancers in patients on dialysis and after kidney transplantation

Comparison of the incidence of skin cancers in patients on dialysis and after kidney transplantation

Kaposi sarcoma: A continuing conundrum

Imiquimod 5% cream for treatment of HIV-negative Kaposi's sarcoma skin lesions: A phase I to II, open-label trial in 17 patients

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