Incidence and characteristics of segmental postsystolic longitudinal shortening in normal, acutely ischemic, and scarred myocardium

Voigt, Jens‐Uwe; Lindenmeier, Gerd; Exner, B; Regenfus, Matthias; Werner, Dierk; Reulbach, Udo; Nixdorff, Uwe; Flachskampf, Frank A.; Daniel, Werner G.

doi:10.1016/s0894-7317(03)00111-1

Cited by 278 publications

(239 citation statements)

References 20 publications

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“…5,11 The technique of TDI was also combined with SRI to search for PSS, or delayed longitudinal contraction. 10,23 The presence of PSS in the basal LV segments was found to correlate with the gain in ejection fraction in 25 patients receiving CRT. 10 In that study, ejection fraction (but not volumetric data) was used as an indicator of reverse remodeling.…”

Section: Tdi Pss Sri and Reverse Remodelingmentioning

confidence: 99%

“…The PSS actually described a contractile response observed during early diastole after closure of the aortic valve. 23 Therefore, it is a semiquantitative and indirect marker of systolic asynchrony. Furthermore, occurrence of PSS has been described in normal subjects who had no evidence of cardiac disease.…”

Section: Tdi Pss Sri and Reverse Remodelingmentioning

confidence: 99%

“…Furthermore, occurrence of PSS has been described in normal subjects who had no evidence of cardiac disease. 23 Also, none of the SRI parameters predict reverse remodeling. Tsr reflects the time to peak regional deformation by contractile force and theoretically will be affected by asynchronous contraction but not affected by translational movement.…”

Section: Tdi Pss Sri and Reverse Remodelingmentioning

confidence: 99%

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Tissue Doppler Imaging Is Superior to Strain Rate Imaging and Postsystolic Shortening on the Prediction of Reverse Remodeling in Both Ischemic and Nonischemic Heart Failure After Cardiac Resynchronization Therapy

et al. 2004

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Background-A number of noninvasive techniques have been used to predict the effectiveness of cardiac resynchronization therapy (CRT) in heart failure patients, in particular left ventricular (LV) reverse remodeling. This study compared the relative predictive values of tissue Doppler imaging (TDI) and strain-rate imaging (SRI) parameters for LV reverse remodeling in patients who received CRT and examined for potential differences in ischemic (nϭ22) and nonischemic (nϭ32) heart failure. Methods and Results-TDI and SRI were performed at baseline and 3-month follow-up. Eighteen parameters of intraventricular and interventricular asynchrony based on the time to peak myocardial contraction (Ts) and time to peak strain rate (Tsr) were compared, along with postsystolic shortening (PSS). Reverse remodeling with reduction of LV end-diastolic and end-systolic volumes and gain in ejection fraction (all PϽ0.001) was observed in the whole study population. The standard deviation of Ts of 12 LV segments (Ts-SD) is the most powerful predictor of reverse remodeling in both the ischemic (rϭϪ0.65, PϽ0.001) and nonischemic (rϭϪ0.79, PϽ0.001) groups. The PSS of 12 LV segments was a good predictor only for the nonischemic (rϭϪ0.64, PϽ0.001) but not the ischemic (rϭ0.32, PϭNS) group. However, parameters of SRI and interventricular asynchrony failed to predict reverse remodeling. By multiple regression analysis, independent parameters included Ts-SD in both groups (PϽ0.005) and PSS of 12 LV segments in the nonischemic group (Pϭ0.03). The area of the receiver operating characteristic curve was largest for Ts-SD (0.94; CIϭ0.88 to 1.00). Conclusions-Ts-SD is the most powerful predictor of LV reverse remodeling and was consistently useful for ischemic and nonischemic heart failure. However, PSS is useful only for nonischemic pathogenesis, whereas the role of SRI parameters was not supported by the present study.

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Section: Tdi Pss Sri and Reverse Remodelingmentioning

confidence: 99%

Section: Tdi Pss Sri and Reverse Remodelingmentioning

confidence: 99%

Section: Tdi Pss Sri and Reverse Remodelingmentioning

confidence: 99%

See 1 more Smart Citation

Tissue Doppler Imaging Is Superior to Strain Rate Imaging and Postsystolic Shortening on the Prediction of Reverse Remodeling in Both Ischemic and Nonischemic Heart Failure After Cardiac Resynchronization Therapy

et al. 2004

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“…On the other hand, PSS does occur in approximately one-third of the normal population. 31 Voigt et al reported that pathologic PSS and physiologic PSS were distinguished by using the cut-off value of 90 ms for the duration. 31 Our study results demonstrated that the best cut-off value for the delay in the displacement peak was 100 ms for DADI, which was in good agreement with the cut-off value for abnormal PSS using strain rate reported by Voigt et al 31 In theory, displacement is inherently affected by tethering (ie, motion from the adjacent myocardium).…”

Section: Discussionmentioning

confidence: 99%

Detection of Diastolic Abnormality by Dyssynchrony Imaging Correlation With Coronary Artery Disease in Patients Presenting With Visibly Normal Wall Motion

Onishi

Uematsu

Nanto

et al. 2009

Circ J

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Background Post-systolic shortening (PSS) is a sensitive indicator of myocardial ischemia. Methods and ResultsWe have developed a tissue Doppler imaging technique that portrays PSS, and whether PSS correlates with coronary artery disease (CAD) was investigated in 186 patients presenting with chest pain and normal echocardiograms. Delays of the displacement peaks from end-systole were calculated in the apical views and displayed from green (0 ms) to red (≥100 ms): detection of diastolic abnormality by dyssynchrony imaging (DADI). CAD was judged positive by DADI when the left ventricular segments were color-coded red. Patients subsequently underwent thallium-201 myocardial perfusion single-photon emission computed tomography (n=150), coronary angiography (CAG, n=74), or both (n=37). CAD(-) was defined as negative scintigraphy test and/or no significant coronary artery stenosis by CAG. In 43 patients (23%), CAD(+) was confirmed by CAG as >75% diameter stenosis. DADI predicted CAD with sensitivity of 60%, specificity of 75%, predictive accuracy of 72%, positive predictive value of 42%, and negative predictive value of 86%. Among 74 patients who underwent CAG, sensitivity was best for the left anterior descending artery. Conclusions DADI detected the regional diastolic abnormality, which correlated with the presence of CAD in patients presenting with visibly normal wall motion. (Circ J 2009; 73: 125 -131)

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“…These are replaced by local early diastolic thickening and shortening, known as postsystolic strain. Several studies have shown that the combination of reduced peak systolic strain with significant increase in postsystolic strain is a highly sensitive marker for acute ischemia [7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Diagnostic Value of 2D Strain Imaging In Patients with Suspected Coronary Artery Disease

Teferici¹,

Qirko²,

Petrela³

et al. 2014

Open Access Maced J Med Sci

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Incidence and characteristics of segmental postsystolic longitudinal shortening in normal, acutely ischemic, and scarred myocardium

Cited by 278 publications

References 20 publications

Tissue Doppler Imaging Is Superior to Strain Rate Imaging and Postsystolic Shortening on the Prediction of Reverse Remodeling in Both Ischemic and Nonischemic Heart Failure After Cardiac Resynchronization Therapy

Tissue Doppler Imaging Is Superior to Strain Rate Imaging and Postsystolic Shortening on the Prediction of Reverse Remodeling in Both Ischemic and Nonischemic Heart Failure After Cardiac Resynchronization Therapy

Detection of Diastolic Abnormality by Dyssynchrony Imaging Correlation With Coronary Artery Disease in Patients Presenting With Visibly Normal Wall Motion

Diagnostic Value of 2D Strain Imaging In Patients with Suspected Coronary Artery Disease

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