Incidence and characteristics of newly diagnosed rheumatic heart disease in Urban African adults: insights from the Heart of Soweto Study

Sliwa, Karen; Carrington, Melinda; Mayosi, Bongani M.; Zigiriadis, Elias; Mvungi, Robert; Stewart, Simon

doi:10.1093/eurheartj/ehp530

Cited by 203 publications

(153 citation statements)

References 17 publications

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“…Despite a reduction in RHD as a cause of HF in SSA in recent years, it remains endemic on our continent. [13] The mainstay of treatment for patients with symptomatic valvular heart disease is surgery, complemented by anti-failure therapy and secondary prevention of rheumatic fever with penicillin in RHD. All patients should be referred for evaluation for surgery.…”

Section: Valvular Heart Diseasementioning

confidence: 99%

Heart failure in sub-Saharan Africa: A clinical approach

et al. 2015

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Section: Valvular Heart Diseasementioning

confidence: 99%

Heart failure in sub-Saharan Africa: A clinical approach

et al. 2015

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“…[6] A study undertaken in 2006 and 2007 by the Adult Cardiology Unit at Chris Hani Baragwanath Academic Hospital (CHBAH), Soweto, which deals with patients older than 14 years, showed a high incidence of new patients (23.5/100 000) presenting with RHD for the first time. [7] In contrast, there has been a noticeable decline of ARF and RHD among children under the age of 14 years at the same hospital over the past two decades. Although the hospital mainly serves the population of Soweto and patients referred from several secondary hospitals in southern and eastern Gauteng and North West Province, the perception is that most patients with severe disease requiring open-heart surgery do not originate from these areas.…”

mentioning

confidence: 99%

Rheumatic fever and rheumatic heart disease in Gauteng on the decline: Experience at Chris Hani Baragwanath Academic Hospital, Johannesburg, South Africa

Cilliers

2014

S Afr Med J

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Background. The incidence of rheumatic fever (RF) and its complications has waned over the past three to four decades throughout the Western world, but RF remains a problem in developing countries and in the indigenous populations of some well-resourced countries. A marked decline in children presenting with acute rheumatic fever (ARF) and chronic rheumatic heart disease (RHD) has been observed over the past two decades at Chris Hani Baragwanath Academic Hospital (CHBAH) in southern Gauteng Province, South Africa, which mainly serves the periurban population of Soweto. Objectives. To analyse the observed decline in ARF and RHD, and consider the reasons for the decrease. Methods. Review of children with ARF and RHD captured on a computerised database of all children seen in the Paediatric Cardiology Unit at CHBAH during 1993 -2010. Results. The records of 467 children with ARF and RHD were retrieved from the database. The majority provided addresses in Gauteng, Soweto and North West Province. The number of children documented to have ARF or RHD declined from 64 in 1993 to 3 in 2010. Onethird of the patients underwent surgery, the majority mitral valve repair. Most of the patients requiring surgery had addresses in parts of Gauteng other than Soweto and other provinces, with relatively few originating from Soweto. Conclusion. The decline in the number of children with ARF and RHD presenting to CHBAH may be attributed to an improvement in socioeconomic conditions and better access to medical care for the referral population over the past two decades.

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“…Making the first episode of rheumatic heart disease a notifiable condition should therefore be considered. 1 The addition of the first episode of rheumatic heart disease as a notifiable condition would provide a complete national picture of the incidence of rheumatic fever and rheumatic heart disease in South Africa.…”

Section: What Is To Be Done?mentioning

confidence: 99%

The Four Pillars of Rheumatic Heart Disease Control

Mayosi

2010

S Afr Med J

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Incidence and characteristics of newly diagnosed rheumatic heart disease in Urban African adults: insights from the Heart of Soweto Study

Cited by 203 publications

References 17 publications

Heart failure in sub-Saharan Africa: A clinical approach

Heart failure in sub-Saharan Africa: A clinical approach

Rheumatic fever and rheumatic heart disease in Gauteng on the decline: Experience at Chris Hani Baragwanath Academic Hospital, Johannesburg, South Africa

The Four Pillars of Rheumatic Heart Disease Control

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