The purpose of the present work is twofold. On a first stage, it aims at highlighting the corruption-related issues in terms of its definitions and different perceptions with respect to some economic theories, while stressing the specific factors lying behind the spread of such practice in the Arab countries. Actually, an emphasis has been put through this research on poverty, illiteracy, low incomes, poor governance, absence of strong powerful institutions and State of right and democracy, more generally the prevalence of a rent based economy, in addition to the impact of special socio-cultural beliefs and practices pertinent to Arab countries that constitute the major reasons leading to the aggravation of such blight throughout the whole region. Moreover, relying on an empirical study based on panel data model over the period 2005 to 2010, this paper tends to show that there does really exist a statically-significant relationship between the riser development size in corruption measured by the corruption perception index as a dependent variable, and the human development index, press freedom index and inflation rate as independent variables. On a second stage, some regulatory recommendations have been advanced within the scope of this work, likely to help fight against such a phenomenon by pointing out and curbing its subjacent latent roots, thus drawing these countries efforts, precautions measures and attention more on the rather preventive measures i.e. on economic policy and institutional reforms while stressing the role of taking further incentives.