Inappropriate Use of Intravenous PPI for Stress Ulcer Prophylaxis in an Inner-city Community Hospital

Effects of pharmacy resident led education on resident physician prescribing habits associated with stress ulcer prophylaxis in non-intensive care unit patients

“…2,3,[6][7][8][9][10][11] Studies report 65-69% of non-ICU patients do not meet criteria for SUP nor have an indication for acid-suppressive therapy. A retrospective analysis (n = 279) found that 204 (73%) patients were prescribed SUP without an appropriate indication, with 140 (69%) patients continuing upon discharge.…”

“…20 A small, inner city community hospital calculated a possible savings of $18,337 annually when they analyzed appropriate use in 1472 patients. 8 In this study, we will assess the effectiveness of education on medical residents' prescribing of SUP in non-ICU patients at a small, nonprofit hospital.…”

Inappropriate Usage of Intravenous Proton Pump Inhibitors and Associated Factors in a High Complexity Hospital in Brazil

“…The inappropriate use of IV PPIs has been observed in various studies, especially in cases without the suspicion of UGIB (4,(11)(12)(13)(14) . There are, however, studies demonstrating that oral preparations of PPIs have similar efficacy to IV preparations in cases of bleeding ulcers suggesting that it seems to be no need for such an excessive IV administration in hospitals resulting undoubtedly to higher institutional costs (15)(16)(17) .…”

Patterns of Use of Prophylaxis for Stress-Related Mucosal Disease in Patients Admitted to the Intensive Care Unit

“…25 Another study at a different institution found an estimated annual saving of $102 895 in patient charges and $11 333 in actual drug costs, in a trauma ICU, attributable to the implementation of appropriate stress ulcer prophylaxis guidelines. 26 Other studies have also addressed the issue of overuse of stress ulcer prophylaxis in the ICU and non-ICU setting 25,[27][28][29][30][31][32] (Table 5). In 2003, Schupp et al studied 814 general adult medicine patients in a community hospital setting; 324 patients received IV PPI for stress ulcer prophylaxis.…”

“…33 Table 5 summarizes other recent studies on stress ulcer prophylaxis. 25,[27][28][29][30][31][32] Only 2 studies reported prospective data 27,29 ; one involved patients in non-ICU settings, 27 and the other included patients in ICU and non-ICU settings. 29 Inappropriate use of stress ulcer prophylaxis was seen in 20% to 80% of patients in various studies 25,[27][28][29][30][31][32] (Table 5).…”