INAEME: Integral Neoantigen Analysis with Entirety of Mutational Events
Vladimir Kovacevic,
Ognjen S. Milicevic,
Nevena M. Ilic Raicevic
et al.
Abstract:Neoantigens are peptides on the surface of cancer cells presented to the immune system. Multiple novel therapeutic approaches involve the identification and administration of neoantigens to trigger immunity-induced tumor regression. Here, we present the novel, integral bioinformatic analysis workflow for neoantigen discovery, denoted INAEME (Integral Neoantigen Analysis with Entirety of Mutational Events). The workflow performs integral processing of an individual’s DNA tumor-normal and RNA tumor raw reads in … Show more
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