Inadequate safety reporting in pre‐eclampsia trials: a systematic evaluation

Abstract

Developing @coreoutcomes could help to improve safety reporting in #preeclampsia trials. @NIHR_DC.

A systematic review on reporting outcomes and outcome measures in trials on synthetic mesh procedures for pelvic organ prolapse: Urgent action is needed to improve quality of research

“…A protocol including explicitly defined objectives, study selection criteria, and data extraction methods was developed. The protocol was informed by other evaluations in pre‐eclampsia, endometriosis, obstetrics, and urogynecology . Ethical approval for this study was not required.…”

Variation in outcome reporting across studies evaluating interventions for selective fetal growth restriction

“…The recent investigation of variation in outcome reporting across studies evaluating treatments for twin‐to‐twin transfusion syndrome (TTTS) highlighted the high variability in the outcomes reported and their definition. Similar heterogeneity in outcome reporting has been identified in studies of other conditions related to women's and newborns' health, including pre‐eclampsia, childbirth trauma and endometriosis. There is a need for a focused effort to improve the quality of research studies on multiple pregnancy complications and their treatment.…”

“…Since this intervention is increasingly being offered to mothers, it is important to be able to assess the risk of maternal and procedural complications and it is possible that these complications might differ in frequency following fetoscopy for sFGR compared to fetoscopy for TTTS. Inadequate safety reporting is a common pattern in studies of outcome reporting, but in order to fully evaluate the balance of risks and benefits it is vital that potential harms, as well as benefits, of each intervention are reported.…”

Do we need a core outcome set for childbirth perineal trauma research? A systematic review of outcome reporting in randomised trials evaluating the management of childbirth trauma

“…Although previously the variation in outcome reporting has been investigated and confirmed in several areas relevant to obstetrics and gynaecology, no evaluation has been undertaken in childbirth trauma research …”

“…11 Although previously the variation in outcome reporting has been investigated and confirmed in several areas relevant to obstetrics and gynaecology, no evaluation has been undertaken in childbirth trauma research. [11][12][13][14][15] We therefore evaluated outcome and outcome measure reporting across published randomised controlled trials evaluating interventions for childbirth trauma. In addition, we investigated associations between outcome reporting quality and other factors, including year of publication, journal impact factor, and methodological quality.…”