In vivo ultrasound backscattering estimation for tumour diagnosis: An animal study

Romijn, R.; Thijssen, J.M.; Delft, J. L. Van; Wolff-Rouendaal, D. De; Best, Jaap van; Oosterhuis, J. A.

doi:10.1016/0301-5629(89)90100-2

Cited by 33 publications

(16 citation statements)

References 17 publications

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“…The estimation of the frequency-dependent backscatter coefficient p+* (f, x) was performed using a short-time Fourier analysis technique [26] with the following equation:…”

Section: Backscatter Coeficient Estimationmentioning

confidence: 99%

“…Existing work which has measured the backscatter coefficient compensated for the attenuation in biological tissue has often been in vitro and has relied upon measurements of the attenuation acquired using a second transducer or a reflector on the opposite side of the tissue specimen [13], [14], [ 171, [24]. In vivo backscatter coefficient measurements have generally either neglected attenuation effects [26], [27] or have compensated backscatter with an in vitro estimation of the attenuation [16]. Researchers have just recently begun to use in vivo measurements of attenuation for the compensation of backscatter.…”

Section: Introductionmentioning

confidence: 99%

“…First, the method for the measurement of attenuation described by Yao et al [12] requires knowledge of the attenuation in the reference phantom across the bandwidth of measurements, while the method described here [5] does not. Secondly, in place of a calculation, the work presented here makes use of a measurement of the backscatter coefficient of the reference phantom [lo], [26] in order to separate it from the backscatter coefficient of the specimen of interest. These two choices provide an approach applicable even if the acoustic properties of the reference phantom are unknown.…”

Section: Introductionmentioning

confidence: 99%

“…0885-3010/96$05.00 0 1996 IEEE The goal of this paper is to further the progress toward the clinical use of the backscatter coefficient and attenuation for tissue characterization over a broad range of frequencies (2 to 60 MHz). Existing techniques [4]-[6], [lo], [26] are adapted and combined in order to measure the frequency-dependent attenuation and backscatter coefficients in a single-transducer backscatter configuration. The backscatter coefficient of a well-characterized phantom was predicted using the theoretical development of Faran [l] and compared to the experimental measurements.…”

Section: Introductionmentioning

confidence: 99%

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Absolute backscatter coefficient over a wide range of frequencies in a tissue-mimicking phantom containing two populations of scatterers

Roberjot

Bridal

Laugier

et al. 1996

IEEE Trans. Ultrason., Ferroelect., Freq. Contr.

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Abstruct-The acquisition and interpretation of in vivo ultrasonic measurements in tissue encounter problems associated with limited access to the region of interest, intermixed scattering structures with different characteristic dimensions, and systemdependent effects. This work addresses these problems by adapting and testing a technique for measuring the absolute attennation and the absolute backscatter coefficient (effective backscatter cross section per unit volume of material), as a function of frequency, in a single-transducer backscatter configuration. The frequency-dependent attenuation and backscatter coefficients of a tissue-mimicking gelatin phantom containing a random distribution of two populations of scatterers were measured. Three transducers with different center frequencies and focusing characteristics were used in order to verify that system-dependent effects were removed by the technique and to investigate the change in the measured parameters across a broad range of frequencies (2 to 60 MHz). A spherical autocorrelation model was applied to measurements of the backscatter coefficient in order to estimate the size of scatterers. Measurements demonstrate that the backscatter and attenuation properties of a mixture of two distinct intermixed scatterer-size populations change as a function of the frequency range across which the model is applied. Comparison of both the magnitude and the frequency dependence of the experimental results with the theoretical prediction of the backscatter coefficient showed good agreement.

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“…The estimation of the frequency-dependent backscatter coefficient p+* (f, x) was performed using a short-time Fourier analysis technique [26] with the following equation:…”

Section: Backscatter Coeficient Estimationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Absolute backscatter coefficient over a wide range of frequencies in a tissue-mimicking phantom containing two populations of scatterers

Roberjot

Bridal

Laugier

et al. 1996

IEEE Trans. Ultrason., Ferroelect., Freq. Contr.

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show abstract

“…The estimation of the frequency-dependent backscatter coefficient ,u&(f.r) was performed using a short time Fourier analysis technique [6] with the following equation:…”

Section: Backscatter Coefficient Estimationmentioning

confidence: 99%

Attenuation and backscatter coefficient measurements from 2 to 60 MHz using backscattered RF signals from a tissue-mimicking phantom

Bridal

Roberjot²,

Laugier³

et al.

1996 IEEE Ultrasonics Symposium. Proceedings

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A technique for measuring the amnuation and the absolute magnitude of backscatter in a singletransducer backscatter configuration is tested in a tissuemimicking gelatin phantom containing two random distributions of spherical glass scatterers (82 pm and 4 pm mean diameter). Three transducers with different center frequencies and focusing characteristics were used in order to verify that system-dependent effects were removed by the technique and to investigate the change in the measured parameters across a broad range of frequencies (2 to 60 MHz). Comparison of both the experimental results with the calculated backscatter magnitude and the dependence on frequency of the coefficient [l] showed good agreement. Thus, the test demonstrates that the backscatter method employed for coefficient is accurate over a broad range of frequencies the determination of the attenuation and backscatter of interest in medical ultrasound and backscatter acoustic microscopy.

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Ultrasonic Tissue Characterization

Thijssen

2002

Acoustical Imaging

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In vivo ultrasound backscattering estimation for tumour diagnosis: An animal study

Cited by 33 publications

References 17 publications

Absolute backscatter coefficient over a wide range of frequencies in a tissue-mimicking phantom containing two populations of scatterers

Absolute backscatter coefficient over a wide range of frequencies in a tissue-mimicking phantom containing two populations of scatterers

Attenuation and backscatter coefficient measurements from 2 to 60 MHz using backscattered RF signals from a tissue-mimicking phantom

Ultrasonic Tissue Characterization

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