In vivo tracking and biosafety of fluorescent graphene-cyclodextrin nanomaterials on zebrafish embryos

Neri, G.; Iaria, Carmelo; Capparucci, Fabiano; Capillo, Gioele; Pennisi, Rosamaria; Nicosia, Angelo; Mineo, Placido; Scala, Angela; Sciortino, Maria Teresa; Piperno, Anna; Marino, Fabio

doi:10.1016/j.flatc.2022.100411

Cited by 3 publications

(1 citation statement)

References 57 publications

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“…In line with this research topic, here, we describe the synthesis and characterization of cationic β-cyclodextrin-functionalized CNTs (CNT-CDs). − The ability of CDs to form stable host-guest inclusion complexes , was combined with the design of a suitable recognition element (ferrocenylcarnosine (FcCAR) , ) that can act as a guest, allowing the fine-tuning of specific features for electrochemical sensing. FcCAR was designed considering three main characteristics: (1) the electroanalytical properties of the Fc unit; (2) the high affinity of CAR for heavy metals , ; and (3) the high affinity of CD cavities for the Fc unit ( K ≈ 10 3 M), which allows efficient inclusion by supramolecular interactions.…”

Section: Introductionmentioning

confidence: 99%

Screen-Printed Carbon Electrodes with Cationic Cyclodextrin Carbon Nanotubes and Ferrocenyl-Carnosine for Electrochemical Sensing of Hg(II)

Abate,

Neri,

Scala

et al. 2023

ACS Appl. Nano Mater.

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The study reports the use of nanoassembly based on cationic cyclodextrin carbon nanotubes (CNT-CDs) and ferrocenylcarnosine (FcCAR) for electrochemical sensing of Hg(II) in aqueous solution. β-cyclodextrins (CDs) were grafted onto CNTs by a click chemistry reaction between heptakis-(6-azido-6-deoxy)-β-cyclodextrin and alkyne-terminated CNTs. The cationic amine groups on the CD units were produced by the subsequent reduction of the residual nitrogen groups. The chemical composition and morphology of CNT-CDs were analyzed by X-ray photoelectron spectroscopy, scanning electron microscopy, and thermogravimetric analysis. A N,N-dimethylformamide dispersion of CNT-CDs was cast on the surface of screen-printed carbon electrodes (SPCEs), and the electrochemical response was evaluated by cyclic voltammetry (CV) using [Fe(CN) 6 ] 3− as the redox probe. The ability of SPCE/ CNT-CD to significantly enhance the electroactive properties of the redox probe was combined with a suitable recognition element (FcCAR) for Hg(II). The electrochemical response of the CNT-CD/FcCAR nanoassembly was evaluated by CV and electrochemical impedance spectroscopy. The analytical performance of the Hg(II) sensor was evaluated by differential pulsed voltammetry and chronoamperometry. The oxidative peak current showed a linear concentration dependence in the range of 1−100 nM, with a sensitivity of 0.12 μA/nM, a limit of detection of 0.50 nM, and a limit of quantification of 1 nM.

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