“…Since the nature of the RTD is different from that of radially-dependent diffuse reflectance signal Rd(r) [88], the spectral interpretation algorithms [95,96] previously developed to extract the hemodynamic and structural properties from Rd(r) is no longer valid. In this study, a new spectral interpretation algorithm was developed for RTD spectra to extract the hemodynamic (hemoglobin concentration, [Hb], and oxygen saturation level, SatO2) and the structural (scattering) properties of the biological tissue.…”