In vivo Studies of Antivival Effect of Tetrapleura tetraptera Extracts on Newcastle Disease Virus

Abstract

Newcastle disease (ND) is an economically important disease of poultry. Vaccination had been the only way of prevention in Nigeria and indeed many countries of the world. Possible therapy is presently lacking. Drugs developed from medicinal chemistry, plant natural products constitute major sources of innovative therapeutic agents for various infectious diseases. Here we studied the in-vivo antiviral effect of Tetrapleura tetraptera (Tt) pods on ND virus in Birds. The aim of this study is to test the ability of this plant to prevent death in Birds. The study employed one (1) phase experimental design. Two concentrations of Tt extract (1.0%, 0.1%) and control were used for treatment in phase 1. All test birds were treated at pre-exposition prophylaxis, at time of prophylaxis Original Research Article