In vivo SPF from multifunctional sunscreen systems developed with natural compounds—A review

Abstract

The effects of ultraviolet (UV) radiation on the skin, arising from sun exposure, have been explored since the previous century. Sunlight consists mainly of infrared (IR), visible, and UV radiation. UV region is divided into three subcategories, that is, UVC, UVB, and UVA. UVC (200-280 nm) is absorbed by the ozone layer in the stratosphere, while UVB and UVA (290-320 and 320-400 nm, respectively) reach the Earth's surface and influence human life and ecosystems. Consequently, human health may be affected under UV exposition. 1,2 In fact, UV exposure leads to health benefits such as production of cholecalciferol (vitamin D3), that is involved in functions

Effect of Fish Bone Bioactive Peptides on Oxidative, Inflammatory and Pigmentation Processes Triggered by UVB Irradiation in Skin Cells

“…A sunscreen provides protection on the entire UV domain (200–400 nm) due to constituent organic and inorganic filters that absorb and reflect, respectively, the UV radiation [ 37 , 38 ]. Plant extracts and, in particular, polyphenolic compounds, such as rutin, ferulic acid and caffeine were clinically tested as natural UV filters and provided enhanced photoprotection to traditional sunscreens, delaying erythema through different mechanisms of antioxidant and anti-inflammatory action [ 38 ]. Gelatin peptides conditioned as nanoparticles played an even more important role than rutin, enhancing the antioxidant/anti-inflammatory results, but showed no efficacy against UVB radiation [ 38 ].…”

“…Plant extracts and, in particular, polyphenolic compounds, such as rutin, ferulic acid and caffeine were clinically tested as natural UV filters and provided enhanced photoprotection to traditional sunscreens, delaying erythema through different mechanisms of antioxidant and anti-inflammatory action [ 38 ]. Gelatin peptides conditioned as nanoparticles played an even more important role than rutin, enhancing the antioxidant/anti-inflammatory results, but showed no efficacy against UVB radiation [ 38 ]. In our study, FBBP preparation presented variable UV absorption, according to its concentration and UV domain.…”

Nano-Structured Lignin as Green Antioxidant and UV Shielding Ingredient for Sunscreen Applications

“…Their use is considered an advantage not only for the ability to improve the SPF value in safer formulations, but also in improving the photostability of traditional UV filters [35]. Secondary metabolites of the cell, such as terpenoids and products of the shikimic acid and polyketide pathways, can play a relevant role bearing conjugated double bonds and aromatic pharmacophores with high UV absorbing and antioxidant properties [36]. They have been selected during molecular evolution by plants and microorganisms in developing defense strategies to minimize the damage of UV radiation and chemical oxidative stresses [37][38][39].…”

New model of biological membrane (shed snakeskin) for studies of antioxidant activity in photoprotective formulation/ Novo modelo de membrana biológica (ecdise de pele de cobra) para estudos de atividade antioxidante em formulação fotoprotetora

“…Recent studies mention antioxidants of plant origin with the additional function of photo-stabilization (MOROCHO-JÁCOME et al 2020). The Forster resonance energy transfer (FRET) technique is an electrodynamic phenomenon, the most frequent in the inhibition of the singlet-singlet energy state.…”