In vivo skin moisturizing measurement by high‐resolution 3 Tesla magnetic resonance imaging

Mesrar, Jawad; Garetier, Marc; Chéchin, D.; Miséry, Laurent; Salem, Douraı̈ed Ben

doi:10.1111/srt.12333

Cited by 6 publications

(7 citation statements)

References 33 publications

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“…Imaging systems such as 7.5 MHz US and magnetic resonance imaging (MRI) exhibit high tissue penetration and also enable visualization of fat and muscle. However, the image information is restricted to structural skin alterations due to lower resolution [5,8]. Furthermore, MRI is time-consuming and not cost-effective for routine use.…”

Section: Research For Clinical Practice Backgroundmentioning

confidence: 99%

Optical coherence tomography for fast bedside imaging, assessment and monitoring of autoimmune inflammatory skin diseases?

Hundt

2020

J Deutsche Derma Gesell

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Summary Optical coherence tomography (OCT) is a non‐invasive, high‐resolution imaging technique with a growing impact in dermatology. The principle of OCT is comparable to that of sonography, except that it uses infrared laser light instead of ultrasound waves. It has been clinically demonstrated that OCT is suitable for discriminating between different types of non‐melanoma skin cancer at an early stage of disease. Optical coherence tomography generates two‐ or three‐dimensional images of up to 2 mm penetration depth, a field of view of 6 mm × 6 mm, and an acquisition time of seconds. The resolution capability of OCT is more than 3 to 100 times higher than that of ultrasound imaging. It is of particular interest that the additional information on vasculature provided by OCT angiography enables the assessment and monitoring of inflammatory skin diseases. The use of OCT to locate exact blister levels was demonstrated for diagnosing autoimmune bullous diseases. It is anticipated that detection of subclinical lesions could indicate a relapse of the disease. In the future, this could enable intervention and early treatment. Furthermore, the development of high‐speed OCT could allow fast scanning and bedside imaging of large body sites.

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Section: Research For Clinical Practice Backgroundmentioning

confidence: 99%

Optical coherence tomography for fast bedside imaging, assessment and monitoring of autoimmune inflammatory skin diseases?

Hundt

2020

J Deutsche Derma Gesell

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“…As this function is wedded to the content of free water, its increase signified betterment in epidermal hydration. Furthermore, the moisturising effect of cosmetic products was investigated by Szayna and Kuhn [147] using high-field MRI and NMR microscopy, and then later by Mesrar et al [148] who examined MRI images acquired in vivo prior to and after moisturiser application, and reported a T2 increase in both SC and epidermis without significant difference in the dermis layer (Figure 3). Although most NMR studies evaluated the entire skin including the dermis, a report by Salter [149] and a similar one by Mirrashed and Sharp [150], visualised the hydration-dehydration process using MRI with a resolution of 0.6 mm after 1 h of skin occlusion.…”

Section: Nuclear Magnetic Resonancementioning

confidence: 99%

“…MRI T2 mapping (seconds); (a) before-with ROI's in the stratum corneum, epidermis and dermis; and (b) 1 h after moisturiser application[148].…”

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confidence: 99%

Review of Modern Techniques for the Assessment of Skin Hydration

Qassem

Kyriacou

2019

Cosmetics

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Skin hydration is a complex process that influences the physical and mechanical properties of skin. Various technologies have emerged over the years to assess this parameter, with the current standard being electrical probe-based instruments. Nevertheless, their inability to provide detailed information has prompted the use of sophisticated spectroscopic and imaging methodologies, which are capable of in-depth skin analysis that includes structural and composition details. Modern imaging and spectroscopic techniques have transformed skin research in the dermatological and cosmetics disciplines, and are now commonly employed in conjunction with traditional methods for comprehensive assessment of both healthy and pathological skin. This article reviews current techniques employed in measuring skin hydration, and gives an account on their principle of operation and applications in skin-related research.

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“…It allows visualizing not only anatomical information but also physical and chemical properties . Previous studies demonstrated the feasibility to explore moisturization with quantification imaging based on T2 mapping …”

Section: Introductionmentioning

confidence: 99%

“…11 Previous studies demonstrated the feasibility to explore moisturization with quantification imaging based on T2 mapping. 11,12 Nevertheless, manual measurements on these maps may be time-consuming, 13 especially if the goal is to study multiple skin layers at a different time. Moreover, quick manual explorations, usually by a small region of interest, are limited to a part of the complete surface of a layer.…”

mentioning

confidence: 99%

Edge detector‐based automatic segmentation of the skin layers and application to moisturization in high‐resolution 3 Tesla magnetic resonance imaging

Mesrar

Benhoumich

Miséry

et al. 2019

Skin Research and Technology

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Introduction Previous studies have demonstrated the feasibility to explore moisturization with quantification imaging based on T2 mapping. The aim of this study was to describe and validate the first robust automated method to segment the first layers of the skin. Materials and Methods Data were picked from a previous study that included 35 healthy subjects who underwent a 3T MRI (multi spin echo calculation T2‐weighted sequence) with a microscopic coil on the left heel before and one hour after moisturization. The automatic algorithm was composed of the T2 map generation, a Canny filter, a selection of boundaries, and a local regression to delimitate stratum corneum, epidermis, and dermis. An automated affine registration was applied between the exams before and after moisturization. Results The failure rate of the algorithm was below 5%. Mean computation time was 139.12s. There was a significant and strong correlation between the automatic measurements and the manual ones for the T2 values (ρ: 0.905, P < 0.001) and for the thickness measurements (ρ: 0.8663; P < 0.001). For registration, mean of the Dice index was 0.64 [0.47; 0.80] and of the Hausdorff distance was 0.29 mm 95% CI: [0.28; 0.30]. Conclusion The proposed automatic method to study the first skin layers in 3T MRI using micro‐coils was robust and described T2 values and thickness measurements with a strong correlation to manual measurements. The use of an automated affine registration could also permit the generation of a mapping for a visual assessment of moisturization.

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In vivo skin moisturizing measurement by high‐resolution 3 Tesla magnetic resonance imaging

Abstract: High-resolution MRI allows fine exploration of anatomical and physiological properties of the skin and can further be used to extend the studies of skin hydration.

Cited by 6 publications

References 33 publications

Optical coherence tomography for fast bedside imaging, assessment and monitoring of autoimmune inflammatory skin diseases?

Optical coherence tomography for fast bedside imaging, assessment and monitoring of autoimmune inflammatory skin diseases?

Review of Modern Techniques for the Assessment of Skin Hydration

Edge detector‐based automatic segmentation of the skin layers and application to moisturization in high‐resolution 3 Tesla magnetic resonance imaging

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