In vivo retention of ingested Au NPs by Daphnia magna: No evidence for trans-epithelial alimentary uptake

Khan, Farhan R.; Kennaway, Gabrielle; Croteau, Marie Noële; Dybowska, Agnieszka; Smith, Brian D.; Nogueira, António J.A.; Rainbow, Philip S.; Luoma, Samuel N.; Valsami-Jones, Eugénia

doi:10.1016/j.chemosphere.2013.12.051

Cited by 59 publications

(52 citation statements)

References 32 publications

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“…Therefore, a direct interaction of MPs with epithelial cells in the digestive tract and thus injuries and a transfer of MPs into the surrounding tissue are unlikely. However, Rosenkranz et al [48] observed 20 and 1,000 nm particles in the oil droplets of D. magna implying a translocation through the gut's epithelial cells, whereas the majority of studies with nanomaterials did not confirm this observation [49,50].…”

Section: Daphnia Magnamentioning

confidence: 88%

Interactions of Microplastics with Freshwater Biota

Scherer

Weber

Lambert

et al. 2017

The Handbook of Environmental Chemistry

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The ubiquitous detection of microplastics in aquatic ecosystems promotes the concern for adverse impacts on freshwater ecosystems. The wide variety of material types, sizes, shapes, and physicochemical properties renders interactions with biota via multiple pathways probable.So far, our knowledge about the uptake and biological effects of microplastics comes from laboratory studies, applying simplified exposure regimes (e.g., one polymer and size, spherical shape, high concentrations) often with limited environmental relevance. However, the available data illustrates species-and materialrelated interactions and highlights that microplastics represent a multifaceted stressor. Particle-related toxicities will be driven by polymer type, size, and shape. Chemical toxicity is driven by the adsorption-desorption kinetics of additives and pollutants. In addition, microbial colonization, the formation of heteroaggregates, and the evolutionary adaptations of the biological receptor further increase the complexity of microplastics as stressors. Therefore, the aim of this chapter is to synthesize and critically revisit these aspects based on the state of the science in freshwater research. Where unavailable we supplement this with data on marine biota. This provides an insight into the direction of future research.In this regard, the challenge is to understand the complex interactions of biota and plastic materials and to identify the toxicologically most relevant characteristics of the plethora of microplastics. Importantly, as the direct biological impacts of This chapter has been externally peer reviewed.

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Section: Daphnia Magnamentioning

confidence: 88%

Interactions of Microplastics with Freshwater Biota

Scherer

Weber

Lambert

et al. 2017

The Handbook of Environmental Chemistry

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show abstract

“…104, 114, 125 However, incomplete depuration of ENPs have been documented in several studies with fish71, 119, 127, 128 (Figure 8) and daphnia113, 114, 126 (Figure 7). Interactions between the ENPs and gut epithelial sorption processes could play a pivotal role in this incomplete depuration.…”

Section: Uptake Internalization and Translocation Of Engineered Namentioning

confidence: 94%

Aquatic Ecotoxicity Testing of Nanoparticles—The Quest To Disclose Nanoparticle Effects

et al. 2016

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The number of products on the market containing engineered nanoparticles (ENPs) has increased significantly, and concerns have been raised regarding their ecotoxicological effects. Environmental safety assessments as well as relevant and reliable ecotoxicological data are required for the safe and sustainable use of ENPs. Although the number of publications on the ecotoxicological effects and uptake of ENPs is rapidly expanding, the applicability of the reported data for hazard assessment is questionable. A major knowledge gap is whether nanoparticle effects occur when test organisms are exposed to ENPs in aquatic test systems. Filling this gap is not straightforward, because of the broad range of ENPs and the different behavior of ENPs compared to “ordinary” (dissolved) chemicals in the ecotoxicity test systems. The risk of generating false negatives, and false positives, in the currently used tests is high, and in most cases difficult to assess. This Review outlines some of the pitfalls in the aquatic toxicity testing of ENPs which may lead to misinterpretation of test results. Response types are also proposed to reveal potential nanoparticle effects in the aquatic test organisms.

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“…A number of invertebrate studies have shown the retention of NPs in the gut lumen without internalization (e.g. Peterson et al, 2009;Galloway et al, 2010;Khan et al, 2014). The differences in biomarker profiles (Fig.…”

Section: Formmentioning

confidence: 96%