In Vivo Proton MR Spectroscopy Evaluation of Pyogenic Brain Abscesses: A Report of 194 Cases

Abstract

BACKGROUND AND PURPOSE:The combination of nonspecific clinical findings and similarities in morphologic appearances on imaging often makes it difficult to distinguish abscesses from other brain lesions. We present a retrospective analysis of in vivo 1 H-MR spectroscopy data for characterization of the etiology of the brain abscess based on the established criteria and demonstrate the sensitivity and specificity of metabolite markers assigned to specific bacterial groups defined by the microbial culture in 194 patients.

A clinical case report of brain abscess caused by Nocardia brasiliensis in a non-immunocompromised patient and a relevant literature review

“…d-e The signal intensity of the lesion ring wall of lesions was slightly increased after enhancement. f CT scan showed irregular low density edema shadows in the right temporal lobe and occipital lobe important markers for diagnosing brain abscess; however, the absence of the three amino acids does not exclude the presence of brain abscess [12,13]. In our report, MRS displayed an elevated lactic acid peak and low NAA, creatine, and choline peaks.…”

A clinical case report of brain abscess caused by Nocardia brasiliensis in a non-immunocompromised patient and a relevant literature review

“…d-e The signal intensity of the lesion ring wall of lesions was slightly increased after enhancement. f CT scan showed irregular low density edema shadows in the right temporal lobe and occipital lobe important markers for diagnosing brain abscess; however, the absence of the three amino acids does not exclude the presence of brain abscess [12,13]. In our report, MRS displayed an elevated lactic acid peak and low NAA, creatine, and choline peaks.…”

In vivo proton MR spectroscopy in uterine abscesses

“…On the other hand, the pyruvate may enter into the tricarboxylic acid cycle in aerobic infection, and may cause the absence of Ac and Suc peaks in the spectra . Pal et al evaluated 194 pyogenic brain abscesses by in vivo MR spectroscopy and observed Ac with or without Suc peaks in most anaerobes and some facultative anaerobes ( S. aureus and Enterococcus faecalis ), whereas Ac and Suc peaks were absent in most aerobes or facultative anaerobes . In our case 2 with facultative anaerobic infection ( S. aureus ), high Ac peak and low Suc peak were observed.…”

Systematic review of neuroparacoccidioidomycosis: The contribution of neuroimaging

“…Acetate and succinate on spectroscopy favour an abscess of anaerobic bacterial origin. These peaks are not observed in fungal infections 50 …”

A clinical case report of brain abscess caused by Nocardia brasiliensis in a non-immunocompromised patient and a relevant literature review

“…d-e The signal intensity of the lesion ring wall of lesions was slightly increased after enhancement. f CT scan showed irregular low density edema shadows in the right temporal lobe and occipital lobe important markers for diagnosing brain abscess; however, the absence of the three amino acids does not exclude the presence of brain abscess [12,13]. In our report, MRS displayed an elevated lactic acid peak and low NAA, creatine, and choline peaks.…”

In vivo proton MR spectroscopy in uterine abscesses

“…On the other hand, the pyruvate may enter into the tricarboxylic acid cycle in aerobic infection, and may cause the absence of Ac and Suc peaks in the spectra . Pal et al evaluated 194 pyogenic brain abscesses by in vivo MR spectroscopy and observed Ac with or without Suc peaks in most anaerobes and some facultative anaerobes ( S. aureus and Enterococcus faecalis ), whereas Ac and Suc peaks were absent in most aerobes or facultative anaerobes . In our case 2 with facultative anaerobic infection ( S. aureus ), high Ac peak and low Suc peak were observed.…”

Systematic review of neuroparacoccidioidomycosis: The contribution of neuroimaging

“…Acetate and succinate on spectroscopy favour an abscess of anaerobic bacterial origin. These peaks are not observed in fungal infections 50 …”

A clinical case report of brain abscess caused by Nocardia brasiliensis in a non-immunocompromised patient and a relevant literature review

“…d-e The signal intensity of the lesion ring wall of lesions was slightly increased after enhancement. f CT scan showed irregular low density edema shadows in the right temporal lobe and occipital lobe important markers for diagnosing brain abscess; however, the absence of the three amino acids does not exclude the presence of brain abscess [12,13]. In our report, MRS displayed an elevated lactic acid peak and low NAA, creatine, and choline peaks.…”

In vivo proton MR spectroscopy in uterine abscesses

“…On the other hand, the pyruvate may enter into the tricarboxylic acid cycle in aerobic infection, and may cause the absence of Ac and Suc peaks in the spectra . Pal et al evaluated 194 pyogenic brain abscesses by in vivo MR spectroscopy and observed Ac with or without Suc peaks in most anaerobes and some facultative anaerobes ( S. aureus and Enterococcus faecalis ), whereas Ac and Suc peaks were absent in most aerobes or facultative anaerobes . In our case 2 with facultative anaerobic infection ( S. aureus ), high Ac peak and low Suc peak were observed.…”

Systematic review of neuroparacoccidioidomycosis: The contribution of neuroimaging

“…Acetate and succinate on spectroscopy favour an abscess of anaerobic bacterial origin. These peaks are not observed in fungal infections 50 …”