“…Non-steroidal anti-inflammatory drugs (NSAIDs), opioid analgesics and co-analgesics such as corticosteroids, neuroleptics, benzodiazepines, local anaesthetics, capsaicin and clonidine are the commonly used analgesics (Sriraj et al, 2018). Regular use of NSAIDs causes adverse side effects such as inflammation of gastrointestinal tract, renal failure and liver toxicity (Khanum et al, 2019). Studies have shown that opiate analgesics cause physical dependence, tolerance and addiction (Hijazi et al, 2017).…”