In vivo MRS study of intraventricular tumors

Abstract

Purpose: To evaluate the role of MR spectroscopy (MRS) as a noninvasive tool for characterization of intraventricular brain tumors. tumor each of rhabdoid tumor, glioneuronal hamartoma, GBM, hemangiopericytoma, and subependymoma II), were studied by MRS before surgery using a pointresolved spectroscopic sequence (PRESS).Results: Statistically significant differences (P < 0.03) were observed for NAA/Cr and Cho/Cr between CNCs and OIV. A significant difference (P < 0.01) was observed in the presence of Gly between the CNCs and meningiomas, and CNCs and OIV. In addition, the presence of Ala was also significantly different (P < 0.01) between OIV and meningiomas, and OIV and CNCs. Conclusion:The present study has shown that MRS can be useful in characterizing intraventricular tumor and distinguishing CNCs from meningiomas and other intraventricular tumors. Prior information about intraventricular tumor types could be useful to clinicians in planning treatment and resection strategy.

Subependymomas – Characteristics of a “Leave me Alone” Lesion

“…Cystic interior elements could be observed in 4 cases of our population, just as described in individual studies [18]. Partial T2* signal reduction as a sign of calcification or hemosiderin deposits were evident in 9 of 33 cases (it should be noted that no T2* sequences of the tumor region were available for 15 of the 33 patients); both calcifications and hemorrhages have already be described for individual cases [10,12,16,18,22]. In addition, no calcifications could be determined in the 5 available CT examinations.…”

In vivo spatially localized high resolution 1H MRS via intermolecular single‐quantum coherence of rat brain at 7 T

“…IN VIVO MAGNETIC RESONANCE SPECTROSCOPY (MRS) as a noninvasive tool can provide spectral information about biochemical composition of tissues and has been used for pathogenesis investigation and clinical diagnostics (1, 2). A high‐resolution nuclear magnetic resonance (NMR) spectrum cannot be achieved unless the magnetic field is extremely homogeneous over the acquisition region (3).…”

Intraventricular tumors - silent or noisy cerebral pathology?

“…The discovery and evaluation of an intraventricular tumor poses is challenging, as a correct diagnosis and management is often difficult [1][2][3][4][5][6][7][8][9][10]. They are rare and have many overlapping imaging features.…”