In vivo methods and applications of xenon-129 magnetic resonance

Marshall, Helen; Stewart, Neil J.; Chan, Ho‐Fung; Rao, Madhwesha; Norquay, Graham; Wild, Jim M.

doi:10.1016/j.pnmrs.2020.11.002

Cited by 37 publications

(52 citation statements)

References 294 publications

(273 reference statements)

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“…The current research predominant contained four topics, but the research did not stop there. For example: some researchers tried to define what “long COVID” is [ 21 , 70 ]; some researchers worked to diagnose long COVID [ 71 ]. It is foreseeable that more literature will be published in the near future, which will make our understanding of long COVID more comprehensive.…”

Section: Discussionmentioning

confidence: 99%

Global Trends and Research Hotspots in Long COVID: A Bibliometric Analysis

Jin

Fan

2022

IJERPH

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Long COVID is a condition distinguished by long-term sequelae that occur or persist after the convalescence period of COVID-19. During the COVID-19 pandemic, more and more people who tested positive for SARS-CoV-2 experienced long COVID, which attracted the attention of researchers. This study aims to assess the pattern of long COVID research literature, analyze the research topics, and provide insights on long COVID. In this study, we extracted 784 publications from Scopus in the field of long COVID. According to bibliometric analysis, it is found that: developed countries in Europe and America were in leading positions in terms of paper productivity and citations. The International Journal of Environmental Research and Public Health and the Journal of Clinical Medicine were leading journals in the perspective of publications count, and Nature Medicine had the highest number of citations. Author Greenhalgh T has the highest number of papers and citations. The main research topics were: pathophysiology, symptoms, treatment, and epidemiology. The causes of long COVID may be related to organ injury, inflammation, maladaptation of the angiotensin-converting enzyme 2 (ACE2) pathway, and mental factors. The symptoms are varied, including physical and psychological symptoms. Treatment options vary from person to person. Most patients developed at least one long-term symptom. Finally, we presented some possible research opportunities.

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Section: Discussionmentioning

confidence: 99%

Global Trends and Research Hotspots in Long COVID: A Bibliometric Analysis

Jin

Fan

2022

IJERPH

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“…In vivo applications and physical principles of this modality have been the subject of numerous reviews published in recent years. [147,148] Until now, only one publication has explored the 19 F- 129 Xe MRI combination with OFI as a third modality. The design of the probe relied on the PFOB-nanoemulsion system (Figure 54).…”

Section: Trimodal 129 Xe Hyper-cest/ 19 F Mri/ofimentioning

confidence: 99%

¹⁹F MRI Probes for Multimodal Imaging**

Janasik

Krawczyk

2021

Chemistry A European J

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Magnetic resonance imaging (MRI) is one of the most powerful imaging tools today, capable of displaying superior soft‐tissue contrast. This review discusses developments in the field of 19F MRI multimodal probes in combination with optical fluorescence imaging (OFI), 1H MRI, chemical exchange saturation transfer (CEST) MRI, ultrasonography (USG), X‐ray computed tomography (CT), single photon emission tomography (SPECT), positron emission tomography (PET), and photoacoustic imaging (PAI). In each case, multimodal 19F MRI probes compensate for the deficiency of individual techniques and offer improved sensitivity or accuracy of detection over unimodal counterparts. Strategies for designing 19F MRI multimodal probes are described with respect to their structure, physicochemical properties, biocompatibility, and the quality of images.

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“…MRI with hyperpolarized gases, Xenon-129 ( 83 ) and Helium-3 ( 84 ), provides unique diagnostic information on the human lung ( 85 , 86 ). Imaging the gas distribution provides ventilation maps in 3D with high resolution ( Figure 5 ), measuring the diffusion allows to assessing the lung microstructure, e.g.…”

Section: Mrimentioning

confidence: 99%

Imaging Inflammation – From Whole Body Imaging to Cellular Resolution

et al. 2021

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Imaging techniques have evolved impressively lately, allowing whole new concepts like multimodal imaging, personal medicine, theranostic therapies, and molecular imaging to increase general awareness of possiblities of imaging to medicine field. Here, we have collected the selected (3D) imaging modalities and evaluated the recent findings on preclinical and clinical inflammation imaging. The focus has been on the feasibility of imaging to aid in inflammation precision medicine, and the key challenges and opportunities of the imaging modalities are presented. Some examples of the current usage in clinics/close to clinics have been brought out as an example. This review evaluates the future prospects of the imaging technologies for clinical applications in precision medicine from the pre-clinical development point of view.

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In vivo methods and applications of xenon-129 magnetic resonance

Abstract: Graphical abstract

Cited by 37 publications

References 294 publications

Global Trends and Research Hotspots in Long COVID: A Bibliometric Analysis

Global Trends and Research Hotspots in Long COVID: A Bibliometric Analysis

¹⁹F MRI Probes for Multimodal Imaging**

Imaging Inflammation – From Whole Body Imaging to Cellular Resolution

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In vivo methods and applications of xenon-129 magnetic resonance

Abstract: Graphical abstract

Cited by 37 publications

References 294 publications

Global Trends and Research Hotspots in Long COVID: A Bibliometric Analysis

Global Trends and Research Hotspots in Long COVID: A Bibliometric Analysis

19F MRI Probes for Multimodal Imaging**

Imaging Inflammation – From Whole Body Imaging to Cellular Resolution

Contact Info

Product

Resources

About

¹⁹F MRI Probes for Multimodal Imaging**