Abstract:A stimuli-responsive
polymeric three-dimensional microstructured
film (PTMF) is a 3D structure with an array of sealed chambers on
its external surface. In this work, we demonstrate the use of PTMF
as a laser-triggered stimulus-response system for local in vivo targeted
blood vessels stimulation by vasoactive substances. The native vascular
networks of the mouse mesentery were used as model tissues. Epinephrine
and KCl were used as vasoactive agents that were sealed into individual
chambers upon precipitation … Show more
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