In Vivo Evaluation of Tissue Protrusion by Using Optical Coherence Tomography and Coronary Angioscopy Immediately After Stent Implantation

Abstract

necrotic core would be easily disrupted and can protrude between stent struts, resulting in an irregular protrusion. 6 However, irregular protrusion has not yet been validated by macroscopic pathology and histology. Coronary angioscopy (CAS) has allowed for the direct visualization of the intracoronary structure and provided substantial information pertaining to macroscopic pathology in living patients. 7 Therefore, the aim of the present study was to assess the relationship between the characteristics of tissue protrusion detected by using OCT and the findings of CAS immediately after stent implantation and in the chronic phase. Methods Study Design This study was retrospectively conducted in our institution from January 2012 to February 2018. We performed OCT

Intravascular Imaging Findings After PCI in Patients With Focal and Diffuse Coronary Artery Disease

“…Importantly, IP has been identified as an independent predictor of target lesion revascularization, underscoring its clinical relevance. 10 , 33 , 34 However, it must be recognized that despite the independent association between PPG and IP, the predicted capacity of PPG to detect IP was modest (area under the curve of 0.66). We also found that vessels with diffuse CAD (low PPG at baseline) had a higher prevalence of ISA after PCI.…”

Comparative Clinical Implications of Calcified versus Non-Calcified Tissue Protrusion After Coronary Stent Implantation

“…While prior IVUS research posits a contributory role for stent type and design in TP prediction, 34 several studies contradict, citing negligible variations in TP rates across diverse stent types and designs. 3 , 4 , 22 , 35 This study underscores that neither the metal composition nor the structural design of the stent is as critical as the inherent lesion morphology or the rigor of the implantation methodology.…”

“…Coronary angioscopies have revealed a correlation between OCT-identified TP post-stent deployment and the presence of advanced yellow plaque thrombotic activity. 22 , 23 Calcified nodules represent another prevalent plaque morphology within lesions accompanied by TPs. This study underscored a heightened incidence of calcified nodules within calcified TPs.…”

“…Conversely, prior IVUS and OCT investigations disclosed no significant correlation between TP and adverse clinical events. 3 , 4 , 17 , 18 , 22 , 38 …”

Clinical Impact of Irregular Protrusion Angle After Coronary Stenting at Culprit Lesions With ST-Elevation Myocardial Infarction ― An Intravascular Optical Coherence Tomography Study ―

“…Recently, combined OCT and angioscopic analysis for tissue protrusion revealed that yellow plaque was observed at a significantly higher rate in OCT-detected IP. 27 Fourth, it is often challenging to discriminate thrombus from protruding tissue, including IP, that is generated from a necrotic core using OCT. Previous research suggested a close association between thrombus and IP.…”