In vivo evaluation of experimental myocardial infarcts by ungated computed tomography

Huber, D.; Jf, Lapray; Hessel, SJ

doi:10.2214/ajr.136.3.469

Cited by 48 publications

(10 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Subsequently, over days and weeks, necrotic myocardium is replaced by fibrous and/or fatty tissue, which is also characterised by a reduction of attenuation in CT in a CTCA, compared with normal myocardium [36, 37]. A number of initial reports on the application of CT in patients with myocardial infarction have been promising, including early animal studies [38–40] and experiences with electron beam (EB) CT [41–43]. With the introduction of multislice CT systems, myocardial viability imaging using CT has experienced renewed interest, with several early case reports showing the capability of the technique to detect myocardial infarctions [44, 45].…”

Section: Ct Viability Und Perfusionmentioning

confidence: 99%

MRI and CT in the diagnosis of coronary artery disease: indications and applications

et al. 2010

View full text Add to dashboard Cite

In recent years, technical advances and improvements in cardiac computed tomography (CT) and cardiac magnetic resonance imaging (MRI) have provoked increasing interest in the potential clinical role of these techniques in the non-invasive work-up of patients with suspected coronary artery disease (CAD) and correct patient selection for these emerging imaging techniques. In the primary detection or exclusion of significant CAD, e.g. in the patient with unspecific thoracic complaints, and also in patients with known CAD or advanced stages of CAD, both CT and MRI yield specific advantages. In this review, the major aspects of non-invasive MR and CT imaging in the diagnosis of CAD will be discussed. The first part describes the clinical value of contrast-enhanced non-invasive CT coronary angiography (CTCA), including the diagnostic accuracy of CTCA for the exclusion or detection of significant CAD with coronary artery stenoses that may require angioplastic intervention, as well as potentially valuable information on the coronary artery vessel wall. In the second section, the potential of CT for the imaging of myocardial viability and perfusion will be highlighted. In the third and final part, the range of applications of cardiac MRI in CAD patients will be outlined.

show abstract

Section: Ct Viability Und Perfusionmentioning

confidence: 99%

MRI and CT in the diagnosis of coronary artery disease: indications and applications

et al. 2010

View full text Add to dashboard Cite

show abstract

“…A number of early reports on the application of computed tomography (CT) in patients with myocardial infarction have been promising, including animal studies [10,11] and experiences with electron beam CT [12,13]; however, the clinical application of CT in the diagnosis of myocardial infarctions has not become popular thus far. With the introduction of multidetector-row computed tomography (MDCT) systems, a drastic improvement in performance as compared to conventional single-slice helical CT scanners could be achieved [14,15].…”

Section: Detection Of Myocardial Infarctions With Mdctmentioning

confidence: 99%

Assessment of myocardial perfusion and viability from routine contrast-enhanced 16-detector-row computed tomography of the heart: preliminary results

et al. 2005

View full text Add to dashboard Cite

To assess the diagnostic accuracy of 16-detector-row computed tomography (16DCT) of the heart in the assessment of myocardial perfusion and viability in comparison to stress perfusion magnetic resonance imaging (SP-MRI) and delayed-enhancement magnetic resonance imaging (DE-MRI). A number of 30 patients underwent both 16DCT and MRI of the heart. Contrast-enhanced 16DCT data sets were reviewed for areas of myocardium with reduced attenuation. Both CT and MRI data were examined by independent reviewers for the presence of myocardial perfusion defects or myocardial infarctions (MI). Volumetric analysis of the hypoperfusion areas in CT and the infarct sizes in DE-MRI were performed. According to MRI, myocardial infarctions were detected in 11 of 30 cases, and perfusion defects not corresponding to an MI were detected in six of 30 patients. CTA was able to detect ten of 11 MI correctly (sensitivity 91%, specificity 79%, accuracy 83%), and detected three of six hypoperfusions correctly (sensitivity 50%, specificity 92%, accuracy 79%). Assessing the volume of perfusion defects correlating to history of MI on the CT images, a systematic underestimation of the true infarct size as compared to the results of DE-MRI was found (P<0.01). Routine, contrast-enhanced 16-detector row CT of the heart can detect chronic myocardial infarctions in the majority of cases, but ischemic perfusion defects are not reliably detected under resting conditions.

show abstract

“…As the attenuation values throughout the myocardium are known to reflect myocardial perfusion [15], the same is true for the myocardium. Experiments from the early days of cardiac CT indicated detection, sizing, and dating of MI feasible with ungated single-slice CT systems [16]. As the attenuation values throughout the myocardium are known to reflect myocardial perfusion [15], this is the most straightforward approach towards the assessment of myocardial perfusion and infarction.…”

Section: Discussionmentioning

confidence: 99%

Perfusion weighted color maps for enhanced visualization of myocardial infarction by MSCT: preliminary experience

Mahnken

Lautenschläger

Fritz

et al. 2008

Int J Cardiovasc Imaging

View full text Add to dashboard Cite

show abstract

In vivo evaluation of experimental myocardial infarcts by ungated computed tomography

Cited by 48 publications

References 6 publications

MRI and CT in the diagnosis of coronary artery disease: indications and applications

MRI and CT in the diagnosis of coronary artery disease: indications and applications

Assessment of myocardial perfusion and viability from routine contrast-enhanced 16-detector-row computed tomography of the heart: preliminary results

Perfusion weighted color maps for enhanced visualization of myocardial infarction by MSCT: preliminary experience

Contact Info

Product

Resources

About