Abstract:Background: Previous studies have reported that the use of a patch in carotid endarterectomy (CEA) surgery can reduce the rate of restenosis and perioperative complications. The goal of this study was to compare the short-and medium-term outcomes of endothelialization and neointimal hyperplasia of patch closure (PC) angioplasty in CEA with direct closure (DC) in a rabbit model. A bovine pericardial patch (BPP) was used in the PC procedures.Methods: Two carotid arteries were dried by air flow to simulate endart… Show more
“…8 Whilst animal studies have demonstrated endothelialisation of BP grafts used for arterial reconstruction, there is a paucity of data relating to endothelialisation of these grafts when used for IVC reconstruction in humans. 9,10 Here we show evidence that BP grafts used for IVC reconstruction demonstrate endothelialisation, however, further larger scale studies are needed to further characterise this finding.…”
Section: Discussionmentioning
confidence: 70%
“…8 Whilst animal studies have demonstrated endothelialisation of BP grafts used for arterial reconstruction, there is a paucity of data relating to endothelialisation of these grafts when used for IVC reconstruction in humans. 9,10 Here we show evidence that BP grafts used for IVC reconstruction demonstrate endothelialisation, however, further larger scale studies are needed to further characterise this finding.Image 2.Macroscopic view of the liposarcoma encasing the IVC from case 1.Image 3.Macroscopic view of the IVC (arrow) and retroperitoneal tissue from case 2.Image 4.Low power view of graft showing lumen (arrow), endothelialisation, and underlying scar with foreign body reaction (left). High power view of graft showing evidence of endothelialisation (arrow head) (right).…”
There is a paucity of research investigating revision surgery for patients with previous inferior vena cava (IVC) reconstruction using bovine pericardium (BP). To the best of our knowledge, no reports of redo procedures have been published in the medical literature. We describe two cases of redo surgery in patients with previous IVC reconstructions using BP following disease recurrence. The first case underwent resection of the BP graft with a second IVC reconstruction using BP, the second case underwent resection of the BP graft without reconstruction due to extensive thromboses. Neither case experienced perioperative complication or morbidity following their redo procedure, and previous IVC reconstruction with BP did not present significant intraoperative technical challenges. One case showed evidence of endothelialisation of the excised BP graft, however, it was not possible to definitively conclude if endothelialisation was present in the second case. Overall, these cases demonstrate that previous IVC reconstruction using BP should not be considered an absolute contraindication for redo surgery in the context of disease recurrence.
“…8 Whilst animal studies have demonstrated endothelialisation of BP grafts used for arterial reconstruction, there is a paucity of data relating to endothelialisation of these grafts when used for IVC reconstruction in humans. 9,10 Here we show evidence that BP grafts used for IVC reconstruction demonstrate endothelialisation, however, further larger scale studies are needed to further characterise this finding.…”
Section: Discussionmentioning
confidence: 70%
“…8 Whilst animal studies have demonstrated endothelialisation of BP grafts used for arterial reconstruction, there is a paucity of data relating to endothelialisation of these grafts when used for IVC reconstruction in humans. 9,10 Here we show evidence that BP grafts used for IVC reconstruction demonstrate endothelialisation, however, further larger scale studies are needed to further characterise this finding.Image 2.Macroscopic view of the liposarcoma encasing the IVC from case 1.Image 3.Macroscopic view of the IVC (arrow) and retroperitoneal tissue from case 2.Image 4.Low power view of graft showing lumen (arrow), endothelialisation, and underlying scar with foreign body reaction (left). High power view of graft showing evidence of endothelialisation (arrow head) (right).…”
There is a paucity of research investigating revision surgery for patients with previous inferior vena cava (IVC) reconstruction using bovine pericardium (BP). To the best of our knowledge, no reports of redo procedures have been published in the medical literature. We describe two cases of redo surgery in patients with previous IVC reconstructions using BP following disease recurrence. The first case underwent resection of the BP graft with a second IVC reconstruction using BP, the second case underwent resection of the BP graft without reconstruction due to extensive thromboses. Neither case experienced perioperative complication or morbidity following their redo procedure, and previous IVC reconstruction with BP did not present significant intraoperative technical challenges. One case showed evidence of endothelialisation of the excised BP graft, however, it was not possible to definitively conclude if endothelialisation was present in the second case. Overall, these cases demonstrate that previous IVC reconstruction using BP should not be considered an absolute contraindication for redo surgery in the context of disease recurrence.
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