In vivo efficacy of Trachyspermum ammi anticalcifying protein in urolithiatic rat model

Kaur, Tarundeep; Bijarnia, Rakesh Kumar; Singla, Sumit; Tandon, Chanderdeep

doi:10.1016/j.jep.2009.09.015

Cited by 36 publications

(20 citation statements)

References 25 publications

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“…The main ingredient, i.e. isothymol and other active ingredients of crude extract of carum seeds have shown to possess antiaggregatory effects [48], anthelmintic [49], antihyperlipidemic [50], anti-filarial [51], insecticidal [52], kidney stone inhibitory [53], molluscicidal [20], mosquito repellent [54], and nematicidal activities [49].…”

Section: Pai Et Almentioning

confidence: 99%

Effect of Green Tea Leaves (Camellia Sinensis) and Carom Seeds (Trachyspermum Ammi) Extracts on Male Mice Exposed to Diazinon.

Pai

Gupta³

2018

Asian J Pharm Clin Res

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Objective: The present communication is based on herb, namely, Trachyspermum ammi L. belonging to family Apiaceae, commonly known as "Ajowan" or carom seeds, and green tea (Camellia sinensis, Theaceae) for the prevention of intoxication induced with a sublethal dose of diazinon.Methods: Male mice weighing around 6.5 mg/kg body weight were exposed to diazinon, a common pesticide used in plant cultivation. Carom seed and green tea leave extracts were given thereafter to the male mice to check their effect on the toxicity of diazinon.Results: After several weeks of exposure to these herbal extracts, there was a significant change observed in the hematobiochemical parameters with a significant increase in values of serum alanine aminotransferase, aspartate aminotransferase, gamma-glutamyl transferase, alkaline phosphatase, creatine kinase, creatinine, glucose, and cholesterol. In contrast, no significant statistical difference was perceived in the values of all hematobiochemical parameters in mice treated with tea leaves extract, carom seed extract, and tea leave and carom seed extracts except the value of serum cholesterol in mice treated with carum seed extract which decreased as compared to the control group. Conclusion:These findings suggest the importance of the carom seeds and green tea and their combinatorial usage against diazinon toxicity, thus promising these plant products to be promising therapeutic agents against hepatotoxicity, cardiotoxicity, nephrotoxicity, and metabolic disorders due to diazinon toxicity. This also makes the safety of herbal products an important public health issue.

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Section: Pai Et Almentioning

confidence: 99%

Effect of Green Tea Leaves (Camellia Sinensis) and Carom Seeds (Trachyspermum Ammi) Extracts on Male Mice Exposed to Diazinon.

Pai

Gupta³

2018

Asian J Pharm Clin Res

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“…The collected urine were admixed with a drop of concentrated hydrochloric acid and stored at 4 o C. Urine was analyzed as previously described for calcium, [12] phosphate, [13] oxalate, [14] urea, [15] uric acid [16] and citrate. [17] Collection and analysis of serum…”

Section: Collection and Analysis Of Urinementioning

confidence: 99%

Effect of Hordeum vulgare Linn. Seeds on glycolic acid induced urolithiasis in rats

Jignesh¹,

Bharat²,

Sandip³

et al. 2012

Phcog Commn

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“…Some biological effects of T. copticum such as anti-inflammatory (Thangam et al 2003), antifungal (Rasooli et al 2008), antiviral (Hussein et al 2000), anti-nociceptive (Hejazian et al 2008), anti-filarial (Mathew et al 2008), antioxidant activity (Bera et al 2004), analgesic (Kaur et al 2009), antimicrobial (Sharifi-Rada et al 2013) and also several therapeutic effects including anti-tussive (Devasankaraiah 1974), anti-vomiting (Gilani et al 2005), digestive stimulant (Boskabady et al 2003), hepatoprotective (Srivastava et al 1999) and lactogenic (Shaukat et al 2004) have been documented.…”

Section: Introductionmentioning

confidence: 99%

In vitro Plantlet Regeneration from Callus Culture of Trachyspermum copticum

Teymourian

Ebrahimi

Tohidfar

et al. 2017

Plant Tissue Cult. & Biotech.

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The effect of explant sources and plant growth regulators on callus induction and plantlet regeneration of Trachyspermum copticum were explored. Different explants including hypocotyl, cotyledonary node and leaf were cultured on MS supplemented with different combinations and concentrations of plant growth regulators including 2,4-D (0.2-3 0.5 mg/l), NAA (2 mg/l), BAP (1-3 mg/l), Kn (0.5 mg/l) and IAA (0.8 mg/l). The best response for callus induction (100%) as well as quality was observed from cotyldonary node segments cultured on MS supplemented with 2, 4-D at 1 mg/l in combination with Kn at 0.5 mg/l. Calli derived from various explants were subcultured on shoot induction media with different compositions and concentrations of medium. MS without any plant growth regulator promoted the highest frequency of shoot regeneration (100%) and also mean number of developed shoots per explants (3.8) showed the same result. Regenerated shoots were then rooted on three-fourth strength MS with 75% efficiency after 30 days.

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In vivo efficacy of Trachyspermum ammi anticalcifying protein in urolithiatic rat model

Cited by 36 publications

References 25 publications

Effect of Green Tea Leaves (Camellia Sinensis) and Carom Seeds (Trachyspermum Ammi) Extracts on Male Mice Exposed to Diazinon.

Effect of Green Tea Leaves (Camellia Sinensis) and Carom Seeds (Trachyspermum Ammi) Extracts on Male Mice Exposed to Diazinon.

Effect of Hordeum vulgare Linn. Seeds on glycolic acid induced urolithiasis in rats

In vitro Plantlet Regeneration from Callus Culture of Trachyspermum copticum

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