In vivo effects of Trichostatin A – A histone deacetylase inhibitor – On chromatin remodeling during Triturus cristatus spermatogenesis

Burlibaşa, Liliana; Zarnescu, Otilia

doi:10.1016/j.anireprosci.2013.09.003

Cited by 14 publications

(19 citation statements)

References 45 publications

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“…The most common methods for genotoxicity testing on amphibians to detect DNA damage are chromosome aberration assays, micronucleus assays, sister chromatid exchange assays, and so-called comet assays (single cell gel electrophoresis) (120). More recent approaches, including chromatin immunoprecipitation, have provided important insights into epigenetic alterations in male crested newt (Triturus cristatus) spermatogenesis owing to environmental exposures (148); additional research on other taxa would be a welcome addition to our understanding of toxicological exposure in amphibians. Comet assays, which visualize breaks in denatured DNA, have also been used to analyze genotoxicological effects in reptiles and amphibians to a limited extent.…”

Section: Ecotoxicology and Genotoxicologymentioning

confidence: 99%

Conservation Genetics and Genomics of Amphibians and Reptiles

Shaffer

Gidiş

McCartney‐Melstad

et al. 2015

Annu. Rev. Anim. Biosci.

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Amphibians and reptiles as a group are often secretive, reach their greatest diversity often in remote tropical regions, and contain some of the most endangered groups of organisms on earth. Particularly in the past decade, genetics and genomics have been instrumental in the conservation biology of these cryptic vertebrates, enabling work ranging from the identification of populations subject to trade and exploitation, to the identification of cryptic lineages harboring critical genetic variation, to the analysis of genes controlling key life history traits. In this review, we highlight some of the most important ways that genetic analyses have brought new insights to the conservation of amphibians and reptiles. Although genomics has only recently emerged as part of this conservation tool kit, several large-scale data sources, including full genomes, expressed sequence tags, and transcriptomes, are providing new opportunities to identify key genes, quantify landscape effects, and manage captive breeding stocks of at-risk species.

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Section: Ecotoxicology and Genotoxicologymentioning

confidence: 99%

Conservation Genetics and Genomics of Amphibians and Reptiles

Shaffer

Gidiş

McCartney‐Melstad

et al. 2015

Annu. Rev. Anim. Biosci.

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“…The eruption vices of the mandibular wisdom tooth can cause a further imbalance factor within the dento-maxillary system, through the pushing process of the 12-year-old molar towards mesial. Thus, taking into account all the possibilities of negatively influencing the relationship between the constituents of this dento-maxillary system produced by the wisdom tooth, it is mandatory to monitor the position of the germs and their possibility of eruption in rela-tion to what is found mesial of them (1)(2)(3)(4)(5)(6)(7)(8). The distalization of mandible, which is seen as the most frequent dimensional change, is aggravated by odontal pathology (1)(2)(3)(4)(5).…”

Section: Methodsmentioning

confidence: 99%

“…Correct answers: a, b. 6. How do you think the orthodontist should intervene in dento-alveolar disharmonies in patients over the age of 12 years: a.…”

Section: The Age After 12 Years Is the Time When The Resistance Of Thmentioning

confidence: 99%

Theoretical and practical considerations in the treatment of morphofunctional imbalances of dento-maxillary system for the age period after 12 years – preliminary study

Beuran¹,

Pharmacy²,

Ionescu³

et al. 2019

Ro J Med Pract.

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This age period after 12 years is characterized by an increase in all dimensions of all the anatomical structures of the individuals, under the influence of new factors that interfere with the general tonus of the body.Purpose. Thus, in this paper, we approached certain aspects of both theoretical and practical that may occur in the formation and development of dento-maxillary system in the age period of 12 years (after some authors, up to the age of 21 years).Material and method. The study was conducted between May 12 and June 25 2018 with the help of 55 dental practitioners.Results and discussions. The analysis of the answers provided by the participants in the study was performed by means of specific research methods. The results are eloquent and provide an overview of how dental practitioners manage the eruption of the wisdom tooth in the developmental processes of the dento-maxillary system.Conclusions. The eruption of the wisdom tooth is a certain element of growth, which must be taken into account in the future therapeutic approach of the morpho-functional imbalances of the dento-maxillary system.

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“…In the case of the 6-year molar edentation, regardless of its location mandibular and/or maxillary, the fastest treatment is to obtain conventional prosthetic restorations. These can be accomplished in a shorter time, but require preparing of neighboring teeth, and in most cases root canal treatment (1)(2)(3)(4)(5)(6)(7)(8).…”

Section: Purposementioning

confidence: 99%

Single tooth edentation caused by missing of the 6-year mollar (maxillary and/or mandible) – consequences and fix prosthetic treatment solutions

Beuran¹,

Ionescu²,

Eftene³

et al. 2019

Ro J Med Pract.

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The loss of first permanent molars, maxillary and/or mandibular, can lead in time, due to the lack of prosthetic restoration, to a series of complications, some of high gravity, which can cause not only severe difficulties in subsequent prosthetic rehabilitation, but also substantial additional costs for patients.Purpose. Thus, in this material we tried to bring to the attention of dental practitioners the most truthful arguments, for a fixed prosthetic restoration as early and efficient as possible.Material and method. 53 dental practitioners, from different cities of the country, took part in this study conducted between May 2017 and April 2019.Results and discussions. The answers obtained by applying the questionnaire were analyzed statistically and exposed for a better understanding by clear graphical methods.Conclusions. The restoration of this type of single tooth edentation produced by the absence of the 6-yearold molar, regardless of location (maxillary and / or mandibular), is considered by most dental practitioners to be relatively simple, regardless of the therapeutic option selected.

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In vivo effects of Trichostatin A – A histone deacetylase inhibitor – On chromatin remodeling during Triturus cristatus spermatogenesis

Cited by 14 publications

References 45 publications

Conservation Genetics and Genomics of Amphibians and Reptiles

Conservation Genetics and Genomics of Amphibians and Reptiles

Theoretical and practical considerations in the treatment of morphofunctional imbalances of dento-maxillary system for the age period after 12 years – preliminary study

Single tooth edentation caused by missing of the 6-year mollar (maxillary and/or mandible) – consequences and fix prosthetic treatment solutions

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