In Vivo Detection of Lymph Nodes Metastasis of ESCC Using CXCR4-Targeted Tracer [64Cu]Cu-NOTA-CP01
Tukang Peng,
Zhijun Li,
Jiebing Gao
et al.
Abstract:Purpose
Esophageal squamous cell carcinoma (ESCC) frequently exhibits skip metastasis to lymph nodes. While current efforts have primarily focused on diagnosing the primary tumor, there is a deficiency of noninvasive imaging techniques capable of directly detecting metastatic lymph nodes (MLN) in ESCC. Building on our previous demonstration of the specificity of [64Cu]NOTA-CP01 in targeting CXCR4 in ESCC, our aim in this study was to detect MLN in ESCC.
Procedures
The intralymphatic tumor metastasis model was … Show more
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