In-vivo degradation of middle-term highly cross-linked and remelted polyethylene cups: Modification induced by creep, wear and oxidation

Miura, Yoshiaki; Hasegawa, Masahiro; Sudo, Akihiro; Pezzotti, Giuseppe; Puppulin, Leonardo

doi:10.1016/j.jmbbm.2015.06.028

Cited by 20 publications

(9 citation statements)

References 44 publications

(56 reference statements)

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“…At an average followup interval of 10 years, we found an 82% reduction in linear wear rates (0.04 versus 0.22 mm/year), a lower incidence of osteolysis, and improved survivorship among the XLPE liners [16]. Because the XLPE liners used in our study did not incorporate antioxidants, there are concerns that the wear performance of these components and other firstgeneration crosslinked liners may deteriorate over time as a result of in vivo oxidation or cyclic loading [10,32,37]. Because these types of components have been implanted in hundreds of thousands of patients undergoing THA, evaluating the clinical performance of XLPE liners at 15-year followup in the context of a prospective, randomized study is the best way to address contemporary concerns and provide data so clinicians and their patients can make evidencebased decisions.…”

Section: Introductionmentioning

confidence: 72%

Otto Aufranc Award: Crosslinking Reduces THA Wear, Osteolysis, and Revision Rates at 15-year Followup Compared With Noncrosslinked Polyethylene

Hopper

Ho²,

Sritulanondha³

et al. 2018

Clin Orthop Relat Res

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Section: Introductionmentioning

confidence: 72%

Otto Aufranc Award: Crosslinking Reduces THA Wear, Osteolysis, and Revision Rates at 15-year Followup Compared With Noncrosslinked Polyethylene

Hopper

Ho²,

Sritulanondha³

et al. 2018

Clin Orthop Relat Res

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“…As already mentioned, crosslinked/remelted polyethylenes did not contain free radicals at the time of implantation and were expected to be stable to oxidation. Unexpectedly, some recent literature studies reported that measurable levels of oxidation were observed in some retrievals [ 99 , 100 , 101 , 102 , 103 , 104 ]. Two concurrent causes have been tentatively identified to explain such a surprising phenomenon.…”

Section: 1st Generation Highly Crosslinked Polyethylenementioning

confidence: 99%

Ultra-High Molecular Weight Polyethylene: Influence of the Chemical, Physical and Mechanical Properties on the Wear Behavior. A Review

et al. 2017

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Ultra-high molecular weight polyethylene (UHMWPE) is the most common bearing material in total joint arthroplasty due to its unique combination of superior mechanical properties and wear resistance over other polymers. A great deal of research in recent decades has focused on further improving its performances, in order to provide durable implants in young and active patients. From “historical”, gamma-air sterilized polyethylenes, to the so-called first and second generation of highly crosslinked materials, a variety of different formulations have progressively appeared in the market. This paper reviews the structure–properties relationship of these materials, with a particular emphasis on the in vitro and in vivo wear performances, through an analysis of the existing literature.

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“…Despite the dynamic development in the field of materials engineering, it was not possible to develop an artificial friction node that would be universal and sufficiently failure-free to be implanted in all patients. Research is constantly being carried out on the introduction of modern materials for the components of artificial joints and the improvement of the lifetime of endoprostheses, with particular emphasis on the friction node [6,7]. The second main current of engineering research is the analysis of the state of stresses and strains in the elements of artificial joints and their impact on tissues [8,9].…”

Section: Introductionmentioning

confidence: 99%

The Analysis of Polyethylene Hip Joint Endoprostheses Strength Parameters Changes after Use inside the Human Body

et al. 2021

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The influence of dynamic loads resulting from human motor activity and electrocorrosion inside the human body on the strength parameters of artificial joint elements has not yet been investigated. Hip joint arthroplasty is the most common surgical procedure in the world that allows doctors to remove pain and restore motor skills in people with severe hip diseases, after accidents, and in the elderly. Based on the reports, this article assesses changes in the number of implanted endoprostheses in the years 2005–2019 and determines the trends and estimated changes in the number of implanted hip prostheses in the following decades. The study assesses changes in selected strength parameters of UHMW-PE polyethylene inserts of hip joint endoprostheses during their use in the human body. The research was carried out on appropriately collected samples from UHMW-PE cups removed from the human body with a known history and lifetime from 4 to 10 years. Patients’ body weight ranged from 735 [N] to 820 [N], and the declared physical activity was similar in the entire research group. As part of the research, the values of changes in dynamic modules and the mechanical loss coefficient were determined in relation to the share of the crystalline and amorphous phases of artificial UHMW-PE cups, removed from the human body after different periods of exploitation under similar operating conditions. The analysis of selected strength parameters was performed at a temperature of 40 °C, which corresponds to the working conditions inside the human body. On the basis of numerical studies, the influence of changes in material parameters on the deformation of the artificial acetabulum during the patient’s motor activity, which is one of the causes of fatigue destruction, was determined.

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In-vivo degradation of middle-term highly cross-linked and remelted polyethylene cups: Modification induced by creep, wear and oxidation

Cited by 20 publications

References 44 publications

Otto Aufranc Award: Crosslinking Reduces THA Wear, Osteolysis, and Revision Rates at 15-year Followup Compared With Noncrosslinked Polyethylene

Otto Aufranc Award: Crosslinking Reduces THA Wear, Osteolysis, and Revision Rates at 15-year Followup Compared With Noncrosslinked Polyethylene

Ultra-High Molecular Weight Polyethylene: Influence of the Chemical, Physical and Mechanical Properties on the Wear Behavior. A Review

The Analysis of Polyethylene Hip Joint Endoprostheses Strength Parameters Changes after Use inside the Human Body

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